Articles tagged "Polyma virus"

2022 American Transplant Congress
RBBP7 as a Novel Biomarker for the Molecular Diagnosis of BK Virus-Associated Nephropathy
W. Yicun, W. Yuxuan, H. Xiaopeng
Department of Urology, Beijing Chaoyang Hospital, Beijing, China
*Purpose: BK virus-associated nephropathy (BKVN) remains a major infectious complication of kidney transplantation, and its histologic appearance can mimic rejection, leading to a diagnostic dilemma…
2022 American Transplant Congress
Clinical Relevance of Absolute BK Polyoma Viral Load Kinetics in Patients with Biopsy Proven BK Polyomavirus Associated Nephropathy
H. Omic¹, J. P. Kläger¹, H. Herkner¹, S. W. Aberle¹, H. Regele¹, L. Weseslindtner¹, T. A. Schrag¹, G. Bond¹, K. Hohenstein¹, B. Watschinger¹, J. Werzowa², R. Strassl¹, M. Eder¹, Z. Kikic¹
¹Medical University of Vienna, Vienna, Austria, ²Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 1st Medical Department, Hanusch Hospital, Vienna, Austria
*Purpose: The absolute BK viral load is an important diagnostic surrogate for BK polyomavirus associated nephropathy (PyVAN) after renal transplant (KTX) and serial assessment of…
2022 American Transplant Congress
De-Novo Belatacept Therapy is Associated with Higher Levels of BK Viremia and Lower Rates of BK Clearance in Kidney Transplantation Patients
G. Petrossian¹, J. Ortiz², K. Addonizio¹, L. Teixeira¹, A. Hsiao¹, R. James³, N. Koizumi³, S. Patel⁴, D. Conti², R. Plews²
¹Albany Medical Center, Albany, NY, ²Division of Renal and Pancreatic Transplant Services, Albany Medical Center, Albany, NY, ³George Mason University, Fairfax, VA, ⁴UMC Las Vegas, Las Vegas, NV
*Purpose: To compare the incidence and severity of BK viremia in kidney transplantation patients with a de-novo belatacept (bela) vs. a no-bela maintenance immunosuppression regimen.*Methods:…
2022 American Transplant Congress
Combined Metagenomic Viral Detection and Donor-Derived Cell-Free DNA Quantification for Solid Organ Transplant Recipients
R. Sinha¹, C. Rebello², E. Bixler¹, A. Al-Turck¹, A. Berg¹, J. Friedewald², S. Kleiboeker¹
¹Eurofins Viracor, Lees Summit, MO, ²Northwestern University, Chicago, IL
*Purpose: Solid organ transplant recipients are predisposed to opportunistic infections, and current viral diagnostic methods focus on sensitive detection of single pathogens by qPCR. However,…
2022 American Transplant Congress
Use of Viral Specific T Cell Therapy in Solid Organ Transplant Recipients – A Single Center Experience
G. McGraw¹, N. Patel², K. Patel¹, S. Bumb³, A. Govil⁴, M. Anand¹
¹University of Cincinnati, Cincinnati, OH, ²Nephrology, University of Cincinnati, Cincinnati, OH, ³Nephrology, Internal Medicine, University of Cincinnati Medical Center, Blue Ash, OH, ⁴Univ of Cincinnati, Cincinnati, OH
*Purpose: Viral infections such as BK virus (BKV), cytomegalovirus (CMV) and adenovirus after kidney transplantation negatively impact outcomes in solid organ transplant (SOT) recipients despite…
2022 American Transplant Congress
Characterization of Kidney Allograft Pathology Using the Histomap Gene Expression Profile (GEP) and Formalin Fixed Paraffin Embedded (FFPE) Tissue
N. Garg¹, K. Degner², H. Zhang³, W. Tian³, F. Aziz⁴, S. Parajuli², W. Zhong², N. Wilson², S. Panzer¹, A. Djamali²
¹University of Wisconsin Madison, Madison, WI, ²University of Wisconsin, Madison, WI, ³CareDx, Brisbane, CA, ⁴University of Wsiconsin, Madison, WI
*Purpose: The new Banff Human Organ Transplant (B-HOT) gene panel assessed on nCounter system has been created through a collaboration between NanoString and the Banff…
2022 American Transplant Congress
Impact of Cytomegalovirus and BK Virus Infection on Clinical Outcomes in Kidney Transplant Recipients
W. Park, J. Yang, J. Kwon, J. Lim, Y. Kim, J. Paek, K. Jin, S. Han
Division of Nephrology, Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Daegu, Korea, Republic of
*Purpose: Cytomegalovirus (CMV) or BK virus (BKV) infection is one of the important opportunistic infections in kidney transplant recipients (KTRs). CMV or BKV infection can…
2021 American Transplant Congress
Transplantation of Hepatitis C Positive Kidney and Pancreas Allografts Into Hepatitis C Naïve Recipients – A Single Center Experience as a Standard of Care
K. Yadav¹, A. Padiyar², K. Zhao³, J. Rabets³, A. Jittirat², S. Sclair⁴
¹Transplant Surgery, University of Toledo Medical Center, Toledo, OH, ²Nephrology, University Hospitals Cleveland, Cleveland, OH, ³Transplant Surgery, University Hospitals Cleveland, Cleveland, OH, ⁴Gastroenterology and Hepatology, University Hospitals Cleveland, Cleveland, OH
*Purpose: Transplantation of Hepatitis C positive organs into Hepatitis C naïve recipients is rapidly gaining widespread acceptance. We report our experience with transplanting HCV D+/R-…
2021 American Transplant Congress
Urine Donor-derived Cell-free is Valuable for Predicting BK Polyomavirus-associated Nephropathy in Kidney Transplant Recipients
G. Huang¹, X. Chen¹, Y. Huang¹, J. Li¹, R. Deng¹, W. Chen², J. Qiu¹, S. Deng¹, G. Chen¹, Q. Fu¹, C. Wu¹, J. Fei¹, L. Liu¹, L. Chen¹, C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Our previous study has proved that urine donor-derived cell-free DNA (dd-cfDNA) can assist in the diagnosis of BK polyomavirus-associated nephropathy (BKPyVAN), but its specificity…
2021 American Transplant Congress
Treatment of Bk Virus With Intravenous Immunoglobulin in Pediatric Kidney Transplant
D. Mohammad, D. Kim, R. Baracco, G. Kapur, A. Jain
Pediatric Nephrology and Transplant Services, Children's Hospital of Michigan, Detroit, MI
*Purpose: To study the prevalence of BK viremia (BKV) and BK Virus Nephropathy (BKVN) utilizing plasma BK quantitative Polymerase Chain Reaction (qPCR) and report outcomes…