2018 American Transplant Congress
Early Association of Low Doses of Tacrolimus and a mTOR Inhibitor in BK Polyomavirus Infection in Kidney Transplant Recipients
Introduction: BK polyomavirus (BKV) replication can be detected in up to 60% of kidney transplant recipients, with an incidence of nephropathy of 5-10%, leading to…2018 American Transplant Congress
Rejection and Graft Loss in Patients with BK Viremia after Simultaneous Pancreas and Kidney Transplant
University of Minnesota, Minneapolis, MN.
Background: BK virus is a recognized cause of kidney allograft dysfunction. The treatment of BK is immunosuppression reduction. This reduction in patients with a simultaneous…2018 American Transplant Congress
Incidence of Rejection and Antibody Formation after Immunosuppression Reduction in Patients with Biopsy Proven Polyomavirus Nephropathy
University of North Carolina, Chapel Hill, NC.
The purpose of this study is to determine the incidence of rejection and donor specific antibody (DSA) formation after immunosuppression reduction in patients with biopsy…2018 American Transplant Congress
CMV and BKV Infections after Kidney Transplantation: Combined Tacrolimus/everolimus Strategy Using Antithymocyte Globulin Induction
Cytomegalovirus (CMV) and BK Virus (BKV) infections are frequent complications after kidney transplantation. A combined regimen of calcineurin inhibitor (CNI) and mTOR inhibitors (mTORi) reduces…2018 American Transplant Congress
Impact of Age and Race on BK Viremia among Kidney Transplant Recipients
Background: Older age has been described as a potential risk factor for BK virus infection after kidney transplantation. The purpose of this study is to…2017 American Transplant Congress
Impact of Everolimus Added to a De Novo Belatacept Regimen on the Risk of BK Viremia After Kidney Transplant.
IntroductionBK viremia is a common complication following kidney transplantation. In vitro data suggest that inhibition of the mTOR–SP6-kinase pathway prevents expression of early viral genes…2017 American Transplant Congress
CMV and BK Virus Infections in Kidney Transplant Recipients Receiving an mTORi-Based Regimen versus a CNI-Based Regimen: A Systematic Review and Meta-Analysis.
The objective of this systematic review is to compare the incidence of CMV and BK virus infections in kidney transplant recipients receiving an mTORi-based as…2017 American Transplant Congress
BK Virus Infection and Risk of Urinary Tract Cancers Among Kidney Transplant Patients in the Transplant Cancer Match Study.
Background: Recent case series describe expression of BK virus (BKV) in tumor tissue obtained from renourinary cancers in kidney transplant recipients (KTRs). Thus, BKV may…2017 American Transplant Congress
BK Polyoma Virus and Malignancy: Cause or Co-Incidence?
Henry Ford Transplant Institute, Detroit, MI
BackgroundThe WHO agency for cancer research has classified BKV as "possibly carcinogenic".The etiological role of BKV in human cancer, however,remains controversial.We present 5 cases of…2017 American Transplant Congress
BK Polyomavirus-Specific 9mer T-Cell Responses Predict Control of Viremia in Kidney Transplant Recipients: First Report from the Swiss Transplant Cohort Study.
BK polyomavirus (BKPyV) causes premature kidney transplant (KT) failure in 1-15% of patients. Since antivirals are lacking, most programs screen KT patients for BKPyV viremia…
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