2018 American Transplant Congress
JC Virus-Associated Nephropathy in Renal Transplant Recipient
Background: JC virus (JCV) inflection is more common than BK virus (BKV) in general population. But in kidney transplants, polyomavirus nephropathy (PVAN) is primarily caused…2018 American Transplant Congress
Comparison of Recipients with Early and Late Presenting Polyomavirus Nephropathy (PVN) with Regard to Histological Findings and Graft Survival: What is the Influence of CD4/CD8 Ratio on the Presenting Time of PVN
Introduction: PVN is a common complication occurring around 12 mo after renal transplant (RT). We aimed to explore the differences between early and late-onset PVN…2018 American Transplant Congress
Long-Term Prognosis of BK Virus Associated Nephropathy in Kidney Transplant Recipients
Background: BK virus-associated nephropathy (BKVAN) is an important risk factor that results in an allograft loss in kidney transplant recipients (KTRs). The short-term prognosis of…2018 American Transplant Congress
Origin and Pattern of Human Polyomaviruses Replication after Kidney Transplantation: A Prospective Study
Background. Human Polyomaviruses (HPyVs) are able to establish latent infection in the kidney of the host. Immunosuppression is recognized risk factor for HPyVs reactivation. Besides…2018 American Transplant Congress
Characteristics of Polyomavirus Nephropathy in Renal Transplant Recipient in China: 10 Year Experience
Background: Till now regular BKV screening after kidney transplantation is not performed in many transplant centers in China. As several noninvasive methods were available in…2017 American Transplant Congress
Which Is More Nephrotoxic to Kidney Transplants: BK Nephropathy or Rejection?
University of Wisconsin, Madison
The relative nephrotoxicity of BK nephropathy (BKN) vs acute rejection is unknown. This is an important question, since clinicians often must choose between reducing immunosuppression…2017 American Transplant Congress
Lack of Specificity of LC-MS/MS Based Urinary Biomarkers for Polyomavirus BK Nephropathy (BKPyVN).
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) based studies have suggested that BKPyVN leads to the excretion of virus-specific urinary peptides which can serve as diagnostic markers…2017 American Transplant Congress
Alemtuzumab Induction Is Associated with a Lower Incidence of BK Virus Nephropathy Compared with IL2RA Induction.
Renal Medicine, West London Renal and Transplant Centre, London, United Kingdom
Introduction:BK polyoma virus associated nephropathy [BKVAN] is a major cause of allograft dysfunction and graft loss occurring in up to 10% of kidney allograft recipients…2017 American Transplant Congress
BKV Clearance Time Correlates with T-Cell Receptor Repertoire Shape and Exhaustion State of BKV-Specific T-Cells in Renal Transplant Patients with Severe BKV Infection.
Reactivation of the BK polyomavirus is known to lead to severe complications in kidney transplant patients. The current treatment strategy relies on decreasing the immunosuppression…2017 American Transplant Congress
Full Dose Cyclosporine Permanently Reverses Uncontrolled BK Viremia That Is Refractory to Tacrolimus Minimization.
Medicine, UCSD School of Medicine, San Diego, CA
Latent BK infection is benign and common in transplanted kidneys, but active infection causes viremia and kidney damage. Standard practice is to reduce tacrolimus (TAC)…
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