ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Polyma virus"

  • 2019 American Transplant Congress

    Impact Of Subclinical Bk Virus-associated Nephropathy In High-risk Recipients

    M. E. Seifert, E. P. Kasik, M. Bernard, G. Agarwal, H. Fatima, R. Gaston, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, F. Rosenblum, G. Towns, R. B. Mannon

    University of Alabama, Birmingham, AL

    *Purpose: BK virus-associated nephropathy (BKVAN) is a major contributor to kidney transplant failure. Surveillance of serum and urine for the BKV genome has been incorporated…
  • 2019 American Transplant Congress

    Late Onset J C Virus Allograft Nephropathy

    M. Samra, I. Tang, S. Setty

    University of Illinois Health, Chicago, IL

    *Purpose: JC virus(JCV) is a member of the Polyomaviridae family. Few studies have been published regarding the replication of JCV in transplant recipients. The incidence…
  • 2019 American Transplant Congress

    Deceased-Donor Acute Kidney Injury Associates with Less BK Viremia in Kidney Transplant Recipients

    I. E. Hall, P. P. Reese, S. G. Mansour, S. Mohan, M. D. Doshi, Y. Jia, H. R. Thiessen-Philbrook, E. Akalin, M. N. Harhay, T. Muthukumar, B. Schröppel, P. Singh, F. L. Weng, J. S. Bromberg, C. R. Parikh

    For the DDS Consortium, Baltimore, MD

    *Purpose: BK viremia (BKV) and polyomavirus nephropathy are kidney transplant complications that contribute to morbidity and graft loss, and prior studies suggest they may be…
  • 2019 American Transplant Congress

    Prolonged Fluoroquinolone Prophylaxis to Prevent BK Viremia in Kidney Transplant Recipients

    S. A. Muhsin1, S. J. Ripley2, M. L. Jacobs3, K. Safa1, D. M. Wojciechowski1

    1Nephrology Division, MGH, Boston, MA, 2Cancer Center, MGH, Boston, MA, 3Wake Forest University School of Medicine, Winston-Salem, NC

    *Purpose: Prophylaxis for kidney transplant recipients has successfully lowered early incidence of infections such as CMV. However, there are no approved agents for the prevention…
  • 2019 American Transplant Congress

    Donor-Derived Cell-Free DNA in Urine Identifies BKVN with Graft Injury in BK Viruria Kidney Transplant Recipients

    G. Huang1, X. Chen1, S. Yang2, W. Chen2, P. Chen3, X. Hou4, T. Jiang5, H. Liu5, X. Li5, C. Wang1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 3Department of clinical laboratory, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 4Guangzhou KingMed Center for Clinical Laboratory Co.,Ltd., Guangzhou, China, 5Research and Development, AlloDx Biotech Co.Ltd., Suzhou, China

    *Purpose: BK Polyomavirus nephropathy (BKVN) is an important cause of dysfunction and failure of renal transplants. Elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the…
  • 2019 American Transplant Congress

    Polyomavirus Genotypes In Renal Transplant Recipients In The United States

    N. Khoury1, C. Thongprayoon2, N. Leeaphorn3, J. Bruminhent4, W. Cheungpasitporn5

    1Henry Ford Transplant Institute, Detroit, MI, 2Mayo Clinic, Rochester, MN, 3University of Missouri, Kansas, MO, 4Mahidol University, Bangkok, Thailand, 5University of Mississippi, Jackson, MS

    *Purpose: BK Polyomavirus (BKV) subtypes and subgroups present uneven geographical distribution, suggesting a potential relationship with ethnicity. In the United States where there is a…
  • 2019 American Transplant Congress

    The Complexity of T Cell-Mediated Rejection Scenarios: Identifying BK in Biopsies with TCMR

    P. F. Halloran and The INTERCOMEX Investigators1, G. Gupta2, J. Reeve3

    1University of Alberta, Edmonton AB, AB, Canada, 2Virginia Commonwealth University, Richmond, VA, 3Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada

    *Purpose: Some transplanted kidneys have concomitant T cell-mediated rejection (TCMR) and BK virus nephropathy (BK). The histologic diagnosis in BK sometimes overlooks the TCMR component,…
  • 2019 American Transplant Congress

    Cidofovir for BK Nephropathy Rescue Treatment: A Single Center Experience

    J. Slatinska1, E. Honsova2, T. Rohal1, A. Slavcev3, P. Hruba4, O. Viklicky1

    1Nephrology, IKEM, Prague, Czech Republic, 2Pathology, IKEM, Prague, Czech Republic, 3Immunology, IKEM, Prague, Czech Republic, 4Transplant Laboratory, IKEM, Prague, Czech Republic

    *Purpose: Cidofovir is a potentially nephrotoxic antiviral drug used primarily as a treatment for CMV retinitis however due to its potent antiviral effects has been…
  • 2019 American Transplant Congress

    Predictors of Response to Intravenous Immunoglobulin for Treatment of Polyoma Nephropathy

    S. Sethi, A. Vo, A. Peng, R. Najjar, K. Lim, S. Jordan, E. Huang

    Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: BK nephropathy is an important cause of allograft dysfunction or loss. IVIg is hypothesized to be effective by providing passive immunity to BK virus…
  • 2019 American Transplant Congress

    Evaluation Of BK Polyomavirus Monitoring And Management In Kidney Transplant Recipients

    M. Tomeczkowicz, S. Mondal, N. Sulejmani, B. Summers, T. Larson, A. Jantz

    Henry Ford Hospital, Detroit, MI

    *Purpose: BK polyomavirus (BKV) is an opportunistic infection that can lead to BKV nephropathy and premature graft loss within the first year post-transplant. The mainstay…
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