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American Transplant Congress abstracts

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Articles tagged "Pediatric"

  • 2018 American Transplant Congress

    Low Kidney Supply to Demand Ratio and Multi-Organ Transplant Centers Are Negatively Associated with Pediatric Renal Transplant Rates Post Kidney Allocation System Implementation: An Analysis of OPTN Data

    P. Almond,1 S. Al-Akash,1 D. Stewart,2 A. Robinson.2

    1CPSST Departments of Surgery and Renal Transplantation, Driscoll Children's Hospital, Corpus Christi, TX; 2UNOS, Richmond, VA.

    Under the new kidney allocation system (KAS), pediatric (PED) renal (REN) transplant (Tx) candidates have priority to kidneys from donors with KDPI < 35%. We…
  • 2018 American Transplant Congress

    Long Term Histologic Allograft Health is Preserved Despite Rejection during Protocolized Immunosuppression Withdrawal (ISW) in Stable Pediatric Liver Transplant Recipients

    V. Venkat,1 J. Bucuvalas,2 M. Martinez,3 K. Spain,4 G. Mazariegos,1 A. Demetris,5 S. Feng.6

    1Children's Hospital, Pittsburgh; 2CCHMC, Cincinnati; 3Columbia, NY; 4Rho, Chapel Hill; 5UPMC, Pittsburgh; 6UCSF, San Francisco.

    Background: Long term allograft health after rejection during ISW has not been previously assessed. We compare baseline and 4yr graft histology of 20 rejectors in…
  • 2018 American Transplant Congress

    The Impact of the Influenza Vaccine on Pediatric Kidney Transplant Outcomes

    M. Camerino,1 S. Jackson,2 S. Chinnakotla,3 P. Verghese.1

    1Department of Pediatrics, University of Minnesota, Minneapolis, MN; 2Fairview Health Services, Minneapolis, MN; 3Department of Surgery, University of Minnesota, Minneapolis, MN.

    The influenza vaccine has been associated with de novo DSA and rejection in adult kidney recipients. This risk has not been adequately assessed in pediatric…
  • 2018 American Transplant Congress

    Large Volume Intraoperative Fluid Use in Small (<20kg) Renal Recipients is Safe

    N. Liow,1 N. Mudalige,2 N. Melhem,1 S. Boyle,1 N. Kessaris,1 H. Hume-Smith,1 S. Marks,1 N. Mamode,1 J. Stojanovic.1

    1Paediatric Nephrology Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom; 2University College London, London, United Kingdom.

    INTRODUCTION: With advances in surgical and medical transplantation, progressively younger children are being transplanted. There is no consensus and little evidence on the optimal intraoperative…
  • 2018 American Transplant Congress

    Distribution of Biopsy Proven Acute Rejection in a Large Pediatric Kidney Transplant Program: A Four Year Experience

    C. Varnell, Jr.,1 A. Carle,2,3 D. Hooper.1,2,3

    1Division of Nephrology & Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 2James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 3Department of Pediatrics, University of Cincinnati, Cincinnati, OH.

    Introduction: Kidney biopsy is the gold standard for diagnosing rejection, transplant glomerulopathy, and other pathology after transplantation. We aimed to understand the distribution of Banff…
  • 2018 American Transplant Congress

    Psychosocial Assessment of Candidates for Transplantation (PACT) Identifies Non-Adherence in Pediatric Kidney Transplantation

    K. Freischlag,1 V. Chen,2 S. Nagaraj,2 A. Chua,2 E. Chambers.2

    1School of Medicine, Duke University, Durham, NC; 2Pediatrics, Duke University, Durham, NC.

    Background: We have demonstrated that overall pre-transplant Psychosocial Assessment of Candidates for Transplantation (PACT) scores can identify high risk pediatric kidney recipients. In this pilot…
  • 2018 American Transplant Congress

    BK Polyomavirus (BKPyV)-Specific T Cells as a Diagnostic and Prognostic Marker for BKPyV-Infections after Pediatric Kidney Transplantation

    T. Ahlenstiel-Grunow,1 M. Sester,2 U. Sester,3 L. Pape.1

    1Pediatric Nephrology, Hannover Medical School, Hannover, Germany; 2Transplant and Infection Immunology, Saarland University, Homburg, Germany; 3Internal Medicine IV, Saarland University, Homburg, Germany.

    After kidney transplantation (KTx) immunosuppressive therapy causes an impaired cellular immune defense resulting in an increased risk of BKPyV-nephropathy (BKPyVAN). Prognostic markers for the outcome…
  • 2018 American Transplant Congress

    T cell Phenotypes Predict Infectious Risk in Transplanted Children

    E. T. Chambers,1 R. Ettenger,2 H.-J. Lee,1 C. Chan,1 L. Stempora,1 B. Warshaw,3 P. Grimm,4 E. F. Reed,2 M. Sarwal,5 A. Kirk.1

    1Pediatrics/Surgery, Duke University, Durham; 2Pediatrics, UCLA, Los Angeles; 3Pediatrics, Emory, Atlanta; 4Pediatrics, Stanford, Palo Alto; 5Surgery, UCSF, San Francisco.

    AIM: Current monitoring strategies do not adequately differentiate infection from complications such as allograft rejection (AR). We aimed to identify peripheral T cell phenotypes that…
  • 2018 American Transplant Congress

    High Tacrolimus Variability is Associated with Worse Outcomes in Pediatric Renal Transplant Recipients

    S. Solomon, M. Del Rio, A. Colovai, N. Hayde.

    Montefiore Medical Center, Bronx, NY.

    Background: Subtherapeutic tacrolimus trough concentrations are associated with donor specific antibody (DSA), acute rejection and shortened graft survival. The role of intrapatient variability in tacrolimus…
  • 2018 American Transplant Congress

    Age Difference between Donor and Recipient Predisposes to Early Interstitial Fibrosis and Tubular Atrophy in Pediatric Kidney Transplantation

    S. Panombualert, M. Pearl, P. Weng, R. Ettenger.

    Pediatric Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

    Introduction: Previous studies in adult kidney transplant recipients (KTRs) have shown that an increased age difference between donor and recipient increases the risk of arterial…
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