Articles tagged "Pancreas"

2017 American Transplant Congress
Impact of Intensive Dosing of Mycophenolate on Pancreas Allograft Survival.
J. Fose,¹ K. Rolling,¹ N. Menninga,¹ G. Leverson,² M. Jorgenson,¹ J. Odorico,² R. Robert.²
¹Pharmacy, UW Health, Madison, WI; ²Transplant Surgery, UW Health, Madison, WI
Purpose: The primary objective was to evaluate the effect of mycophenolate (MPA) dicharge (DC) dose on pancreas allograft (PTX) survival. Secondary endpoints included patient survival…
2017 American Transplant Congress
Insulin Therapy in Pancreas Donors as a Predictor of Subsequent Transplant Outcome.
I. Shapey,¹ H. Khambalia,² A. Summers,² T. Augustine,² M. Rutter,¹ D. van Dellen.¹
¹Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; ²Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom
Introduction: Brain stem death causes high levels of systemic catecholamines and inflammation affecting all organs. These changes, and the routine use of high-dose corticosteroids in…
2017 American Transplant Congress
Kidney Re-Transplant Rate in Simultaneous Kidney Pancreas Transplant Recipients.
M. McCormick, J. Luo, A. Hoffman.
Transplant, University of Nebraska Medical Center, Omaha, NE
Bladder drainage, although no longer the most commonly performed method for exocrine drainage of the pancreas, remains an option for patients undergoing simultaneous pancreas- kidney…
2016 American Transplant Congress
Results of Biopsies in Pancreas and Kidney-Pancreas Patients with Graft Dysfunction.
P. Uva, L. Leon, E. Minue, I. Cabrera, A. Giunippero, M. Norese, M. Toniolo, E. Chuluyan, D. Casadei.
Nephrology, Buenos Aires, Argentina.
In pancreas transplantation there is no reliable laboratory test or imaging study for detection of graft rejection. There is an increasing interest in obtaining pancreas…
2016 American Transplant Congress
Isolating High Islet Mass Even from Alcoholic Pancreatitis Pancreases Intended for Clinical Islet Auto-Transplantation: Improved Strategies to Human Islet Isolation Technique.
A. Balamurugan, G. Loganathan, B. Tweed, W. Tucker, S. Mokshagundam, S. Williams, M. Hughes.
Surgery, Clinical Islet Cell Laboratory, Cardiovascular Innovation Insitute, Louisville, KY.
It has been reported in the literature that after pancreatic resection with planned islet auto-transplantation (IAT), islets isolated from alcoholic pancreatitis (AP) pancreases resulted in…
2016 American Transplant Congress
Risk Factors for Early Readmission After Total Pancreatectomy with Islet Auto Transplantation.
R. Shahbazov,¹ N. Bashoo,² G. Yoshimatsu,² G. Saracino,² F. Azari,¹ N. Onaca,² P. Kim,² M. Levy.³
¹Charles O.Strikler Transplant Center, Department of Surgery, University of Virginia, Charlottesville, VA; ²Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX; ³Transplant Division, Virginia Commonwealth University, Richmond, VA.
Introduction: Readmission after Total Pancreatectomy with Islet Auto Transplantation (TPIAT) is common, but no data is available on reasons for readmission and islet graft function.Aims:…
2016 American Transplant Congress
Surgical Techniques in Modified Multiorgan Transplantation.
W. Ju, J. Lin, J. Zhou, M. Chen, A. Yang, D. Wang, Y. Ma, Z. Guo, M. Han, X. Wang, X. Zhu, X. He.
Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Objective: Investigate the clinical efficacy of combined en-bloc liver-pancreas transplantation in patients with end stage liver disease and diabetes.Method: The clinical data of 19 cases…
2016 American Transplant Congress
FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.
S. Afelik,¹ N. Yonan,¹ B. Pool,² J. Jensen,² J. Oberholzer.¹
¹Surgery, Division of Transplantation, University of Illinois, Chicago, IL; ²Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Foundation, Cleveland, OH.
Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…
2016 American Transplant Congress
A Novel Microfluidic Device for Purification of Pancreatic Islet Preparations.
W. Varhue,¹ L. Langman,² D. Bowers,³ S. Peirce-Cottler,³ N. Swami,¹ K. Brayman.²
¹Electrical and Computer Engineering, University of Virginia, Charlottesville, VA; ²Surgery, University of Virginia, Charlottesville, VA; ³Biomedical Engineering, University of Virginia, Charlottesville, VA.
Purpose: Demonstrate that novel continuous flow microfluidic designs can be utilized to remove contaminating acinar tissue and sort the purified islets, based on size and…
2016 American Transplant Congress
High Resolution Detection of Human Pancreatic Islet Damage During and After Isolation Procedure Using MicroRNAs.
S. Prathab Balaji,¹ M. Kanak,² G. Yoshimatsu,¹ C. Chang,¹ M. Levy,² M. Lawrence,¹ P. Kim,³ N. Onaca,³ B. Naziruddin.³
¹Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; ²Transplant Division, Department of Surgery, VCU Medical Center, Richmond, VA; ³Baylor Simmons Transplant Institute, Dallas, TX.
Background: Pancreatic islets are subjected to stresses throughout isolation procedures that account for considerable variation in quality and yield. Multiparameter methods are needed to monitor…