ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Pancreas"

  • 2017 American Transplant Congress

    The Association of Donor Vasoactive Drugs with Pancreas Transplant Graft Survival.

    I. Shapey,1 P. Yianoullou,2 A. Summers,2 T. Augustine,2 M. Rutter,1 D. van Dellen.2

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom

    Introduction: Vasoactive drugs (VaD) are commonly used to correct abnormal haemodynamics of organ donors in Intensive Care Units (ICU). VaDs can differentially affect insulin secretion…
  • 2017 American Transplant Congress

    Pancreatectomy and Islet Autotransplantation After Combined Split Liver Transplantation and Pancreaticoduodenectomy: A Case Report.

    R. Horneland,1 S. Guvåg,1 O. Korsgren,2 E. Aandahl.1

    1Oslo Univ. Hospital, Oslo, Norway; 2Rudbeck Laboratory Uppsala Univ. Hospital, Uppsala, Sweden

    IntroductionLiver cirrhosis (LC) and common bile duct (CBD) malignancy often require combined liver transplant (LT) and pancreatectomy (PE). Total pancreatectomy (TP) often results in unstable…
  • 2017 American Transplant Congress

    Surgical Techniques for Pancreas Transplantation Graft without Vascular Reconstruction (Report of 8 Cases).

    A. Hu, W. Liao, C. Zhang, X. Zhu, X. He.

    The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    Background / Purpose: Pancreas is complicated by its blood supply and vascular structure. At present, it is necessary to do the vascular remodeling and reconstruction…
  • 2016 American Transplant Congress

    FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.

    S. Afelik,1 N. Yonan,1 B. Pool,2 J. Jensen,2 J. Oberholzer.1

    1Surgery, Division of Transplantation, University of Illinois, Chicago, IL; 2Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Foundation, Cleveland, OH.

    Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…
  • 2016 American Transplant Congress

    A Novel Microfluidic Device for Purification of Pancreatic Islet Preparations.

    W. Varhue,1 L. Langman,2 D. Bowers,3 S. Peirce-Cottler,3 N. Swami,1 K. Brayman.2

    1Electrical and Computer Engineering, University of Virginia, Charlottesville, VA; 2Surgery, University of Virginia, Charlottesville, VA; 3Biomedical Engineering, University of Virginia, Charlottesville, VA.

    Purpose: Demonstrate that novel continuous flow microfluidic designs can be utilized to remove contaminating acinar tissue and sort the purified islets, based on size and…
  • 2016 American Transplant Congress

    High Resolution Detection of Human Pancreatic Islet Damage During and After Isolation Procedure Using MicroRNAs.

    S. Prathab Balaji,1 M. Kanak,2 G. Yoshimatsu,1 C. Chang,1 M. Levy,2 M. Lawrence,1 P. Kim,3 N. Onaca,3 B. Naziruddin.3

    1Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; 2Transplant Division, Department of Surgery, VCU Medical Center, Richmond, VA; 3Baylor Simmons Transplant Institute, Dallas, TX.

    Background: Pancreatic islets are subjected to stresses throughout isolation procedures that account for considerable variation in quality and yield. Multiparameter methods are needed to monitor…
  • 2016 American Transplant Congress

    IgM Treatment Successfully Prevents Type 1 Diabetes by Dysregulation of Pancreatic MicroRNAs with Immunomodulatory Roles.

    P. Chhabra, R. Gehrau, V. Mas, D. Bower, D. Maluf, K. Brayman.

    UVA, Charlottesville.

    Type 1 Diabetes (T1D) is hallmarked by beta-cells destruction. We aimed to identify specific pancreatic microRNAs (miRNA) as potential biomarkers for T1D prediction and diagnosis,…
  • 2016 American Transplant Congress

    Pancreas Transplantation from Pediatric Donors: A UNOS Registry Analysis.

    M. Spaggiari, I. Tzvetanov, H. Jeon, E. Benedetti, J. Oberholzer.

    Division of Transplantation, University of Illinois at Chicago, Chicago.

    Introduction: Major concerns about the utilization of pediatric pancreata are the cumulative islet mass and the increased technical complexity. The primary aim of this study…
  • 2016 American Transplant Congress

    Impact of Early Hospital Readmission Following Simultaneous Pancreas Kidney Transplantation.

    E. King, L. Kucirka, M. McAdams-DeMarco, M. Bowring, A. Massie, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: Our group recently demonstrated that 54% of simultaneous pancreas kidney (SPK) recipients experience early hospital readmission (EHR). It is unknown whether EHR following SPK…
  • 2016 American Transplant Congress

    Simultaneous Pancreas and Kidney Transplantation for Type 2 Diabetes.

    K. Wong, W. Bry, H. Mahanty, P. Patel.

    Transplantation, California Pacific Medical Center, San Francisco, CA.

    Introduction: Type 2 diabetes (T2DM) is characterized initially by insulin resistance and later by beta cell failure. Historically, T2DM has been a relative contraindication for…
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