Articles tagged "Pancreas"

2021 American Transplant Congress
Achilles Heel No Longer: Marked Decline in Early Relaparotomy and Allograft Pancreatectomy Rates Following Simultaneous Kidney-Pancreas Transplantation in the Contemporary Era
B. Sharda¹, K. Gurung², R. Stratta², A. Farney², G. Orlando², C. Jay², A. Reeves-Daniel³, A. Mena-Gutierrez³, N. Sakhovskaya³, W. Doares⁴, S. Kaczmorski⁴, M. Magid⁴, J. Rogers²
¹Wake Forest Baptist Medical Center, Winston Salem, NC, ²Department of Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC, ³Internal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, ⁴Department of Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: Technical complications requiring early relaparotomy (relap) and allograft pancreatectomy (AP) have long been the Achilles heel of simultaneous kidney-pancreas transplantation (SKPT).*Methods: Single center retrospective…
2020 American Transplant Congress
Does Pretransplant C-Peptide Influence Outcomes Following Simultaneous Pancreas-Kidney Transplantation: A Case-Control Study
V. Gurram, K. Gurung, J. Rogers, A. Farney, G. Orlando, C. Jay, A. Reeves-Daniel, A. Mena-Gutierrez, N. Sakhovskaya, W. Doares, S. Kaczmorski, M. Gautreaux, R. Stratta
Abdominal Transplant Surgery, Wake Forest Baptist Health, Winston Salem, NC
*Purpose: The study purpose was to evaluate outcomes in SPKT pts according to presence or absence of pretransplant Cp*Methods: Selection criteria for Cp positive (Cp+,…
2020 American Transplant Congress
Ten Year Results of a Single Center Study of Rabbit Anti-Thymocyte Globulin Compared to Alemtuzumab Induction in Simultaneous Pancreas-Kidney Transplantation
V. Gurram, K. Gurung, G. Orlando, A. Farney, J. Rogers, C. Jay, W. Doares, S. Kaczmorski, A. Reeves-Daniel, A. Mena-Gutierrez, M. Gautreaux, R. Stratta
Abdominal Transplant Surgery, Wake Forest Baptist Health, Winston Salem, NC
*Purpose: The study purpose was to analyze 10-year outcomes of depleting antibody induction agents in simultaneous pancreas-kidney transplant (SPKT) at a single center*Methods: From 2/02…
2020 American Transplant Congress
Clinical and Demographic Factors Affecting Patient and Graft Survival in Pancreas Transplant Recipients: The Efispan Study
P. Ventura-Aguiar¹, M. Cabello², I. Beneyto³, D. Navarro Cabello⁴, G. Tabernero⁵, A. Alonso⁶, J. Ruiz⁷, S. Llorente⁸
¹Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain, ²Department of Nephrology, Hospital Carlos Haya, Malaga, Spain, ³Department of Nephrology, Hospital La Fe, Valencia, Spain, ⁴Department of Nephrology, Hospital Reina Sofía, Cordoba, Spain, ⁵Department of Nephrology, Hospital Universitario de Salamanca, Salamanca, Spain, ⁶Department of Nephrology, Hospital Universitario de A Coruña, A Coruña, Spain, ⁷Department of Nephrology, Hospital Marqués de Valdecilla, Santander, Spain, ⁸Department of Nephrology, Hospital Virgen de la Arrixaca, Murcia, Spain
*Purpose: Pancreas transplantation is an established treatment for diabetic patients with end-stage renal disease. Graft outcomes have improved in the last decades, but data regarding…
2020 American Transplant Congress
Circulating MicroRNA Signatures in Chronic Pancreatitis Patients Undergoing Total Pancreatectomy with Islet Transplantation
S. Vasu, C. M. Darden, K. Kumano, M. Lawrence, B. Naziruddin
Baylor University Medical Ctr, Dallas, TX
*Purpose: Chronic pancreatitis (CP) is characterized by exocrine insufficiency and severe abdominal pain. Total pancreatectomy with islet autotransplantation (TPIAT) relieves chronic pain and aids restoration…
2020 American Transplant Congress
AIPCs Home to and Engraft in the Pancreas When Injected Intravenously
J. B. Pollett¹, N. Thai²
¹Imagine Pharma, Pittsburgh, PA, ²Allegheny Health Network, Pittsburgh, PA
*Purpose: AIPCs (Activated Islet Proliferating Cells) are a recently developed cell population generated from isolated islets of mice and humans. AIPCs are over 65% CD133-,…
2020 American Transplant Congress
Implications for Facilitated Pancreas Transplant Allocation with the Removal of Donor Service Area
R. Forbes¹, R. Urban², A. Fox², J. Odorico³, S. Niederhaus⁴
¹Vanderbilt University Medical Center, Nashville, TN, ²United Network for Organ Sharing, Richmond, VA, ³University of Wisconsin, Madison, WI, ⁴University of Maryland, Baltimore, MD
*Purpose: Facilitated Pancreas (FP) Allocation, modified in August 2016 to be metric-based rather than opt-in, defines an eligible center as one that has transplanted at…
2020 American Transplant Congress
Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study
R. P. Meier, H. Noguchi, Y. Kelly, M. Sarwal, G. Conti, R. Halleluyan, M. Tavakol, P. Stock, C. Freise
Transplant Surgery, University of California San Francisco, San Francisco, CA
*Purpose: Sarcopenia has been identified as a recognized predictive variable for surgical outcomes. We hypothesized that sarcopenia could be a key measure to identify frail…
2020 American Transplant Congress
Lower Extremity Vascular Complications after Simultaneous Pancreas Kidney Transplant
H. J. Braun, D. Amara, T. Sorrentino, J. L. Ramirez, J. Lin, A. Mello, P. G. Stock, J. S. Hiramoto
University of California, San Francisco, San Francisco, CA
*Purpose: Type 1 diabetes mellitus (DM) is the leading indication for simultaneous pancreas kidney transplantation (SPK). Prior work has demonstrated a 2% incidence of lower…
2020 American Transplant Congress
Early Tacrolimus-LCP Conversion Due to Adverse Effects in Pancreas Transplant Recipients Improves Tolerance But Not Graft Survival
J. L. Descourouez, M. R. Jorgenson, D. C. Felix, J. Wiegel, G. E. Leverson, D. A. Mandelbrot, R. R. Redfield, J. S. Odorico
UW Health, Madison, WI
*Purpose: Tacrolimus-LCP (LCPT) is an extended release formulation of tacrolimus which has been shown to have fewer adverse drug effects (ADE) than immediate release tacrolimus…