2015 American Transplant Congress
Optimal Induction Therapy (IT) in Pancreas After Kidney Transplantation (PAK) According to Type of Kidney (kd) Donor and Patient Risk A Registry Analysis
1University of Arizona, Tucson, AZ; 2University of Arizona, Tucson, AZ.
Purpose: Best IT in PAK recipients (rec) according to type of kd donor (LD vs. DD) and rec risk has not been determined.Methods: Using the…2015 American Transplant Congress
Safety and Efficacy of Conversion from Conventional Twice Daily Tacrolimus to Once Daily Extended Release Tacrolimus in Stable Pancreas Transplant (SPK and PAK) Recipients
Surgery, Multi-Organ Transplant, Toronto General Hospital, Toronto, ON, Canada.
Background: A once-daily, modified-release oral formulation of tacrolimus has been developed to simplify dosing and improve medication adherence. There is limited data on the implementation…2015 American Transplant Congress
Post-Donation Outcomes in 46 Live Pancreas Donors
Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN.
Background: Live donor segmental pancreas transplants have been performed selectively to increase the pool of donors, minimize cold ischemia time, and to avoid brain death.…2015 American Transplant Congress
Long Term Follow Up Reveals Satisfactory Renal Outcome in Pacreas After Kidney Transplantation (PAK)
Objective: PAK offers diabetic ESRD patients' opportunity to avoid or minimize dialysis using living kidney donation, followed by cadaveric pancreas transplantation thereafter to restore euglycemia,…2015 American Transplant Congress
Inadequate Overall Immunosuppression Is a Risk for Late Acute Rejection Despite Alemtuzumab Induction in Simultaneous Pancreas Kidney Transplant Recipients
Introduction: Simultaneous pancreas-kidney transplantation (SPK) has become the treatment of choice for patients with end-stage renal disease due to Type 1 Diabetes Mellitus. SPK is…2015 American Transplant Congress
10 Year Experience Using a Steroid Free Three Drug Maintenance Immunosuppression Regimen for Pancreas Transplant Alone: Comparison of Induction With Rabbit Antithymocyte Globulin +/- Rituximab
Graft survival following pancreas transplant alone (PTA) is inferior to other pancreas transplants. Steroid elimination is appealing, but a two drug maintenance strategy may be…2015 American Transplant Congress
Effect of Donor Age On Pancreas Transplantation Outcome
The global increase in the average donor age over the last decade has resulted in widespread acceptance of pancreases from older donors for transplantation. This…2015 American Transplant Congress
Donor Specific Antibodies (DSA) Increase the Risk for Rejection After Pancreas Transplantation Qithout Negatively Impacting Survival
Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.
Donor-specific antibodies (DSA) have been associated with increased rejection and lower kidney transplant survival. The impact of DSA on pancreas transplant outcomes in patients with…2015 American Transplant Congress
Excessive Weight Gain After Pancreas Transplant: Transitioning from Type 1 to Type 2 Diabetes?
AIM:Excessive weight gain (EWG) after pancreas transplantation may increase the risk of post-transplant diabetes mellitus and metabolic syndrome. This study aimed to define the incidence,…2015 American Transplant Congress
Differences in Genetic Variants That Influence Long-Term Graft Function Between Pancreas Transplant Donors and Recipients
Genetic variation in caveolin-1, involved in signal transduction and tissue fibrosis, within pancreas transplant donors has been previously shown to correlate with decreased long-term graft…