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Articles tagged "Pancreas transplantation"

  • 2016 American Transplant Congress

    Center Volume Is Associated with Outcome Following Pancreas Transplantation within the Eurotransplant Region.

    W. Kopp,1,2 M. van Meel,2 H. Putter,3 U. Samuel,2 H. Arbogast,4 W. Schareck,5 J. Ringers,1 A. Braat.1

    1Surgery, Leiden University Medical Center, Leiden, Netherlands; 2Eurotransplant International Foundation, Leiden, Netherlands; 3Medical Statistics, Leiden University Medical Center, Leiden, Netherlands; 4General, Visceral, Transplant, Vascular and Thoracic Surgery, University of Munich – Grosshadern Medical Centre, Munich, Germany; 5University Medical Center Rostock, Rostock, Germany.

    Introduction Outcome following all kinds of surgery depends on several factors, amongst these the annual volume-outcome relationship. This might also be the case in a…
  • 2016 American Transplant Congress

    What Is the Decline Rate of Pancreata Attributed to Donation After Cardiac Death When the Accompanied Kidney Is Transplanted?

    T. Alhamad,1 K. Lentine,2 A. Taha,2 J. Wellen,1 D. Brennan.1

    1Washington University in St. Louis, St. Louis; 2Saint Louis University, St. Louis.

    Background:Pancreas transplantation in the U.S. has declined steadily in the U.S. over the past decade despite international growth of the practice. Reasons for this decline…
  • 2015 American Transplant Congress

    10 Year Experience Using a Steroid Free Three Drug Maintenance Immunosuppression Regimen for Pancreas Transplant Alone: Comparison of Induction With Rabbit Antithymocyte Globulin +/- Rituximab

    J. Fridell,1 R. Mangus,1 J. Chen,2 M. Mujtaba,3 T. Taber,3 M. Goble,1 J. Powelson.1

    1Surgery, Indiana University School of Medicine, Indianapolis, IN; 2Pharmacy, Indiana University School of Medicine, Indianapolis, IN; 3Medicine, Indiana University School of Medicine, Indianapolis, IN.

    Graft survival following pancreas transplant alone (PTA) is inferior to other pancreas transplants. Steroid elimination is appealing, but a two drug maintenance strategy may be…
  • 2015 American Transplant Congress

    Effect of Donor Age On Pancreas Transplantation Outcome

    A. Rathnasamy Muthusamy,1 G. Vrakas,1 S. Mittal,1 S. Reddy,1 I. Quiroga,1 J. Gilbert,1 R. Ploeg,2 E. Sharples,1 S. Sinha,1 A. Vaidya,1 P. Friend.2

    1Transplant Surgery, Churchill Hospital, Oxford, United Kingdom; 2Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom.

    The global increase in the average donor age over the last decade has resulted in widespread acceptance of pancreases from older donors for transplantation. This…
  • 2015 American Transplant Congress

    Donor Specific Antibodies (DSA) Increase the Risk for Rejection After Pancreas Transplantation Qithout Negatively Impacting Survival

    M. Marquez, M. Dib, G. Sapisochin, J. Laurence, A. Barbas, F. Bazerbachi, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattal.

    Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.

    Donor-specific antibodies (DSA) have been associated with increased rejection and lower kidney transplant survival. The impact of DSA on pancreas transplant outcomes in patients with…
  • 2015 American Transplant Congress

    Excessive Weight Gain After Pancreas Transplant: Transitioning from Type 1 to Type 2 Diabetes?

    A. Islam,1 A. Lawless,1 L. Teeter,3 E. Graviss,3 D. Victor,4 A. Sadhu,4 S. Patel,6 A. Gaber,1 R. Knight.1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX; 2Department of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, TX; 3Department of Medicine, Houston Methodist Hospital, Houston, TX; 4Department of Pharmacy, Houston Methodist Hospital, Houston, TX.

    AIM:Excessive weight gain (EWG) after pancreas transplantation may increase the risk of post-transplant diabetes mellitus and metabolic syndrome. This study aimed to define the incidence,…
  • 2015 American Transplant Congress

    Differences in Genetic Variants That Influence Long-Term Graft Function Between Pancreas Transplant Donors and Recipients

    M. Simmonds,1 C. Duff,1 A. Hamilton,1 S. Mittal,2,3,4 M. Barnardo,2,3 S. Fuggle,2,3 P. Friend,2,3 S. Gough.1,4

    1Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom; 3Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 4Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom.

    Genetic variation in caveolin-1, involved in signal transduction and tissue fibrosis, within pancreas transplant donors has been previously shown to correlate with decreased long-term graft…
  • 2015 American Transplant Congress

    Import Pancreas Transplants: Good from Far or Far from Good?

    J. Rogers, A. Farney, G. Orlando, A. Reeves-Daniel, A. Palanisamy, H. El-Hennawy, M. Khan, M. Gautreaux, S. Iskandar, R. Stratta.

    General Surgery-Transplantation, Wake Forest Baptist Medical Center, Winston-Salem, NC.

    Background: Many transplant (tx) programs are reluctant to import pancreas allografts because of concerns that outcomes might be inferior to locally procured organs. Methods: Single…
  • 2015 American Transplant Congress

    Impact of HMOX1 Genetic Variation in Pancreas Transplant Recipients On Long-Term Graft Outcome

    C. Duff,1 A. Hamilton,1 S. Mittal,2,3,4 M. Barnardo,2,3 S. Fuggle,2,3 P. Friend,2,3 S. Gough,1,4 M. Simmonds.1

    1Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom; 3Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 4Oxford National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom.

    Variation within the heme oxygenase 1 (HMOX1) gene, essential for heme catabolism and a known inflammatory and immune regulator, is proposed to play a role…
  • 2015 American Transplant Congress

    Do Induction Therapy, Patient-Level and Post-Operative Factors Impact Outcomes in Moderate to High Immunologic Risk Simultaneous Kidney-Pancreas Transplantation in the Era of Stringent HLA Cross-Matching?

    V. Rohan, D. Taber, D. Taraskiewicz, S. Nadig, J. Mcgillicuddy, K. Chavin, P. Baliga, C. Bratton.

    MUSC, Charleston, SC.

    Background: Simultaneous kidney and pancreas transplantation (SPK) is a lifesaving procedure for patients with diabetes mellitus. The success of SPK is dependent upon minimization of…
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