ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Oxidant stress"

  • 2015 American Transplant Congress

    Relations Among Hyperuricemia, Inflammation, Oxidative Stress and Arterial Stiffness in Renal Transplant Recipients

    B. Gurlek Demirci,1 S. Sezer,1 M. Erkmen Uyar,1 Z. Bal,1 E. Tutal,1 F. Ozdemir Acar,2 M. Haberal.3

    1Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey; 2Department of Nephrology, Baskent University Faculty of Medicine, Istanbul, Turkey; 3Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

    Purpose: Uric acid is the end product of purine metabolism and has well known anti-oxidant effects. Superoxide dismutase (SOD) and malondialdehyde (MDA) are well-known antioxidant…
  • 2015 American Transplant Congress

    The Immunogenic Perlecan Fragment LG3 Is Released Through Apoptotic Extracellular Vesicles Downstream of Caspase-3 Activation

    D. Beillevaire,1 J. Turgeon,1 D. Gingras,2 é. Boilard,3 M. Dieudé,1 M.-J. Hébert.1

    1CNTRP, CRCHUM, Université de Montréal, Montréal, Canada; 2Université de Montréal, Montréal, Canada; 3CNTRP, CHUL, Québec, Canada.

    LG3, a C-terminal fragment of perlecan, has been implicated in aggravation of renal allograft rejection and vascular injury. LG3 is known to be produced at…
  • 2015 American Transplant Congress

    Ex Vivo Lung Perfusion: Revisit to the Optimal Oxygenation Circulating Lungs for Graft Preservation

    K. Noda, S. Haam, J. D'Cunha, J. Luketich, C. Bermudez, N. Shigemura.

    Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

    AimAccumulating evidence supports increasing the role of ex vivo lung perfusion (EVLP). However, there are evidenced limitations as well as the adverse effects of current…
  • 2015 American Transplant Congress

    T Cell Specific Up Regulation of Nrf2 Regulated Antioxidant Response Protects from Kidney Ischemia Reperfusion Injury in Mice

    S. Noel,1 M. Martina,2 S. Bandapalle,1 S. Reddy,3 L. Racusen,2 A. Hamad,2 H. Rabb.1

    1Department of Medicine, Johns Hopkins University, Baltimore, MD; 2Department of Pathology, Johns Hopkins University, Baltimore, MD; 3Department of Pediatrics, University of Illinois, Chicago, IL.

    Background: T lymphocytes mediate important pathophysiological roles during ischemia reperfusion injury (IRI). Transcription factor Nrf2 is protective during experimental kidney IRI and thought to be…
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