Articles tagged "Outcome"

2022 American Transplant Congress
Holes in the Safety-Net: Examining the Path to Kidney Transplantation for Liver Transplant Recipients with Persistent Kidney Dysfunction
A. J. Erhardt, M. J. Hobeika, T. Menser, A. Saharia, O. Okidi, C. Mobley, R. McMillan, L. W. Moore, H. Podder, S. Yi, R. J. Knight, A. Gaber, R. Ghobrial
Department of Surgery; J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX
*Purpose: The 2017 combined liver-kidney allocation modification provided early access to kidney transplantation (KT) for liver transplant (LT) recipients with severe post-LT kidney dysfunction. Although…
2022 American Transplant Congress
Utility of Protocol Pancreas Biopsies for De Novo Donor-Specific Antibodies
S. Parajuli, D. Mandelbrot, J. Odorico
University of Wisconsin, Madison, WI
*Purpose: Donor-specific antibodies (DSA) against the human leukocyte antigens (HLA) can now be measured accurately and repetitively, and are routinely monitored post-transplant. In recipients of…
2022 American Transplant Congress
The Effect of COVID-19 Pandemic in Intestinal Rehabilitation and Transplant Patients – International Multicenter Survey
M. Segovia¹, M. Fernandez², S. Jafri³, T. Schiano⁴, S. Horslen⁵, C. Rumbo², C. Zanfi⁶, A. Testro⁷, L. Sharkey⁸, F. Braun⁹, H. Vilca Melendez¹⁰, R. Sanchez Claria¹¹, L. Ceulemans¹², T. Hibi¹³, D. Ramish², G. Noel¹, G. Dijkstra¹⁴, P. Friend¹⁵, F. Lacaille¹⁶, D. Sudan¹, G. Mazariegos¹⁷, J. Yap¹⁸, G. Herlenius¹⁹, H. Solar², G. Gondolesi²
¹Duke, Durham, NC, ²Favaloro, Buenos Aires, Argentina, ³Henry Ford, Detroit, MI, ⁴Mount Sinai, New York, NY, ⁵UPMC, Edgeworth, PA, ⁶U Bologna, Bologna, Italy, ⁷Austin Health, Melbourne, Australia, ⁸Cambridge, Cambridge, United Kingdom, ⁹Schleswig-Holstein, Kiel, Germany, ¹⁰King's College, London, United Kingdom, ¹¹Hosp Italiano, Buenos Aires, Argentina, ¹²U Leuven, Brussels, Belgium, ¹³Kumamoto Univ, Kumamoto, Japan, ¹⁴U Groningen, Groningen, Netherlands, ¹⁵U Oxford, Oxford, United Kingdom, ¹⁶Necker-Enfants Malades, Paris, France, ¹⁷UPMC, Pittsburgh, PA, ¹⁸U Melbourne, Melbourne, Australia, ¹⁹U Sahlgrenska, Gothenburg, Sweden
*Purpose: It has been proposed that patients with intestinal failure (IF) and intestine transplant (IT) are at higher risk of severe complications of COVID-19 due…
2022 American Transplant Congress
Equivalence of Pediatric Paper and Electronic-Based Patient-Reported Outcome Measures: Findings from a Systematic Review
S. Kortbeek¹, A. Pawaria², V. L. Ng¹
¹Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ²Pediatric Hepatology, Gastroenterology and Liver Transplant, Global Hospitals, Mumbai, India
*Purpose: Integration of patient reported outcome measures (PROMs) in routine clinical care reduces utilisation of health care services and improves patient outcomes. Electronic versions of…
2021 American Transplant Congress
Allograft Discard Risk Index for Lung Transplantation
R. M. Reul, G. Loor, P. S. Garcha, A. A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: The demand for donor lungs continues to outpace the supply, yet nearly 80% of donor lungs consented for lung transplantation (LTx) are discarded.*Methods: We…
2021 American Transplant Congress
Impact of Cypa5 Status on the Clinical and Financial Outcomes of Kidney Transplant
J. Obayemi¹, B. Keating², K. Lentine³, M. Schnitzler³, H. Xiao³, V. Dharnidharka⁴, D. Axelrod⁵
¹Univ of Michigan, Ann Arbor, MI, ²Univ of Pennsylvania, Philadelphia, PA, ³Saint Louis Univ, Saint Louis, MO, ⁴Washington Univ, Seattle, WA, ⁵Univ of Iowa, Iowa City, IA
*Purpose: Pharmacogenetic profiling of transplant recipients has demonstrated marked variation in the metabolism of immunosuppressive medications, particularly tacrolimus. Patients of African ancestry have been found…
2021 American Transplant Congress
Outcomes After Liver Transplantation With Steatotic Grafts: Redefining Acceptable Cutoffs for Moderately Steatotic Grafts
B. L. Da¹, J. Satiya², R. P. Heda³, Y. Jiang⁴, L. Lau⁵, A. Fahmy¹, A. Winnick¹, N. Roth¹, E. Grodstein¹, P. J. Thuluvath⁶, A. K. Singal⁷, T. D. Schiano⁸, L. W. Teperman¹, S. K. Satapathy¹
¹Liver Disease, Northwell Health, Manhasset, NY, ²Beth Israel Deaconess Medical Center, Boston, MA, ³Tulane Medical Center, Memphis, TN, ⁴The University of Memphis, Memphis, TN, ⁵Northwell Health, Manhasset, NY, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷Liver Disease, Avera McKenna University Health Center and Transplant Institute, Manhasset, NY, ⁸Icahn School of Medicine at Mount Sinai, New York City, NY
*Purpose: Graft macro-steatosis can predispose to worse graft survival. Our objective was to redefine acceptable cutoffs for graft steatosis using the national database.*Methods: Data of…
2021 American Transplant Congress
Pig Orthotopic Heart Transplantation (ohtx) in Baboons: Is an Acute Pulmonary Inflammatory Response the Key Problem?
A. Jagdale¹, D. Cleveland², M. Bikhet¹, J. Foote³, G. Walcott⁴, H. Iwase¹, T. Yamamoto¹, H. Hara¹, C. Hansens-Estruch¹, D. Ayares⁵, S. Litovsky⁶, L. Rhodes², W. Carlo⁷, J. Crawford², R. Dabal², S. Borasino², D. Cooper¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Cardiothoracic Surgery, Children's of Alabama, Birmingham, AL, ³Medicine and Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, AL, ⁴Medicine, University of Alabama at Birmingham, Birmingham, AL, ⁵Surgery, Revivicor, Blacksburg, VA, ⁶Pathology, University of Alabama at Birmingham, Birmingham, AL, ⁷Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham, Children's of Alabama, Birmingham, AL
*Purpose: To investigate the mechanism of early cardio-pulmonary dysfunction after genetically engineered pig OHTx in baboons.*Methods: OHTx from pigs expressing different genetic modifications, α‐galactosyltransferase knockout…
2021 American Transplant Congress
The Co-Occurrence of Newly Developed HLA Donor Specific Antibody and Positive C3d/C4d Profiles Along with Immune Therapy Non-Compliance in Pediatric Heart Transplant Recipients is a High Risk Indicator for Patient Mortality
A. Zhang, C. Nasman, J. Allen, Y. Sun, D. Thomas, R. Rodriguez, C. Tan, G. Boyle
Cleveland Clinic Foundation Transplant Center, Cleveland, OH
*Purpose: Increasing evidence has implicated the deleterious effect of HLA donor specific antibody (DSA) in pediatric heart transplantation (PHTx). However, there are still insufficient research…
2021 American Transplant Congress
Covid vs Non Covid Pneumonia in Kidney Transplant Recipients
R. Prashar, N. Khoury, P. Shrivastava, S. Yeddula, T. Kitajima, E. Ulrich, M. Ramesh, A. Patel, S. Nagai, M. Samaniego-Picota
Henry Ford Hospital, Detroit, MI
*Purpose: Compare clinical characteristics and outcomes in kidney transplant recipients (KTRs) hospitalized with COVID vs Non COVID Pneumonia.*Methods: This is a retrospective case‐control study examining…