ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Neutropenia"

  • 2021 American Transplant Congress

    Characteristics, Risk Factors, and Outcomes of Neutropenia for the First Year After Liver or Kidney Transplantation in Children

    C. Jarasvaraparn1, S. Choudhury2, C. Rusch2, K. Liss1, J. Stoll1, S. Hmiel3, S. Kulkarni1

    1Pediatric Gastroenterology, Washington University School in St Louis, Saint Louis, MO, 2Pediatric, Washington University School in St Louis, Saint Louis, MO, 3Pediatric Nephrology, Washington University School in St Louis, Saint Louis, MO

    *Purpose: Prior studies in adults have shown that approximately 20-38 % of subjects undergoing solid organ transplant develop neutropenia. In the current study, we characterized…
  • 2021 American Transplant Congress

    Risk Factors and Outcomes of Neutropenia in Kidney Transplant Recipients

    R. Avery1, J. Motter1, S. Sae-Tia2, N. Lu1, W. Cochran1, A. Massie1, D. Brennan1, F. Akinwande1, S. Shoham1, E. Kraus1, N. Alachkar1, S. Alasfar1, F. Naqvi1, F. Al Ammary1, K. Marr1, S. Mehta Steinke1, N. Desai1, O. Ezennia1, P. Plummer1, C. Durand1, W. Werbel1, M. Y. Kim1, D. Segev1, J. Garonzik Wang1, B. Trollinger1, L. Lees1, L. Toman1, S. Shulder3, K. Dzintars1, D. Ostrander1

    1Johns Hopkins, Baltimore, MD, 2Stony Brook University, Stony Brook, NY, 3University of Rochester, Rochester, NY

    *Purpose: Neutropenia is a common side effect of valganciclovir and may pose increased risk for post-transplant infections. Medications such as mycophenolate and infections such as…
  • 2020 American Transplant Congress

    Evaluation of the Safety and Efficacy of Valganciclovir to Prevent Cytomegalovirus Infection in Pediatric Solid Organ Transplant Recipients Utilizing Two Dosing Regimens

    K. Le, A. Patel, N. M. Jasiak-Panek

    Pharmacy, Ann and Robert H. Lurie Children's Hospital, Chicago, IL

    *Purpose: Valganciclovir (VGCV) is FDA-approved for CMV prophylaxis in children aged one month to sixteen years old using the Pescovitz algorithm (7 x body surface…
  • 2020 American Transplant Congress

    Outcomes in Liver Transplantation with Use of Granulocyte-Colony Stimulating Factor

    K. Schnelle, A. Leino, M. Chunduru, L. Von Stein, O. Witkowsky

    The Ohio State Wexner Medical Center, Columbus, OH

    *Purpose: Questions remain if treatment with a granulocyte-colony stimulating factor (G-CSF) impacts clinical outcomes after liver transplant. The purpose of this study was to compare…
  • 2020 American Transplant Congress

    Safety and Efficacy of Prophylactic Valganciclovir Dosing after Solid Organ Transplant

    K. Gandhi, D. Masic, M. Santarossa, F. Albarillo, N. Clark, G. Reid

    Loyola University Medical Center, Maywood, IL

    *Purpose: At centers where antiviral prophylaxis is used after solid organ transplant, valganciclovir is administered for the prevention of cytomegalovirus (CMV). At Loyola University Medical…
  • 2020 American Transplant Congress

    Granulocyte Colony Stimulating Factor: Trigger of Rejection in Lung Transplantation?

    K. Walter1, M. Patti1, S. Khalid2, L. Kemp1, L. J. Lobo3, R. Coakley3, S. Krishnan3, C. T. Doligalski1

    1University of North Carolina Medical Center, Chapel Hill, NC, 2Eshelman School of Pharmacy, Chapel Hill, NC, 3Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC

    *Purpose: Granulocyte colony stimulating factor (GCSF) is a management strategy for post-transplant neutropenia, but may increase the risk of rejection in lung transplant recipients (LTRs).…
  • 2020 American Transplant Congress

    Renal Transplant Induction Therapy Safety Outcomes Comparison

    R. M. Hofmann1, J. Combs2, K. J. Schmidt3, T. Dyckman4

    1Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, 2Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, 3Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, 4Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI

    *Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
  • 2020 American Transplant Congress

    Filgrastim Utilization Evaluation in Solid Organ Transplant Recipients

    O. Witkowsky, L. Stanz, K. Schnelle

    The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Neutropenia occurs in up to 40% of kidney and liver transplant (txp) recipients and has been associated with higher mortality rates in liver txp.…
  • 2019 American Transplant Congress

    Comparison of Two Dosing Regimens of Valganciclovir for Cytomegalovirus Prophylaxis in High-Risk Liver Transplant Recipients

    A. L. Bixby, L. Fitzgerald, L. Cotiguala, J. M. Park, D. Kaul, C. Sonnenday, S. Tischer

    Michigan Medicine, Ann Arbor, MI

    *Purpose: Significant controversy surrounds the optimal dose and duration of valganciclovir (VGCV) to prevent CMV in high-risk (D+/R-) liver transplant (LT) recipients. High doses cause…
  • 2019 American Transplant Congress

    Efficacy of Filgrastim in Solid Organ Transplant Recipients

    M. Spinner1, K. Gaffney1, S. Gundling2

    1Pharmacy, Cleveland Clinic, Cleveland, OH, 2University of Pittsburgh School of Pharmacy, Pittsburgh, PA

    *Purpose: Neutropenia frequently occurs after solid organ transplantation (SOT) due to immunosuppression, antiviral prophylaxis, or viral infections. Immunosuppression reduction or antiviral prophylaxis minimization can lead…
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