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American Transplant Congress abstracts

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Articles tagged "Neutropenia"

  • 2022 American Transplant Congress

    Cytomegalovirus Prevention in Kidney and Pancreas Transplant Recipients: A Successful Pharmacist-Led Multidisciplinary Approach

    J. Geyston, J. Dann, A. Doyle, A. Agarwal, K. Brayman, C. Shoemaker, C. Lester, S. Rao

    University of Virginia Health, Charlottesville, VA

    *Purpose: In response to high cytomegalovirus (CMV) infection and increasing ganciclovir (GCV)-resistance rate, a pharmacist-led multidisciplinary task force was created to manage CMV prophylaxis (ppx).…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Valacyclovir versus Valganciclovir for CMV Prophylaxis: A Randomized Controlled Trial

    P. S. Verghese1, A. Matas2, S. Chinnakotla2, M. Evans3, H. Balfour Jr4

    1Univ of Minnesota Pediatric Nephrology, Minneapolis, MN, 2Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Biostatistics, University of Minnesota, Minneapolis, MN, 4Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: Valganciclovir (valG) is an effective CMV prophylactic agent post-kidney transplant (KTx) with significant side effects. Valacyclovir (valA) may be effective for CMV prophylaxis with…
  • 2022 American Transplant Congress

    Burden of Leukopenia/Neutropenia Among Adult Kidney Transplant Recipients: A Systematic Literature Review of Observational Studies

    A. Raval1, K. Kistler2, Y. Tang1, F. Vincenti3

    1Merck & Co., Inc., Kenilworth, NJ, 2Xcenda, Inc, Carrollton, TX, 3University of California, San Francisco, San Francisco, CA

    *Purpose: Leukopenia/neutropenia (L/N) may affect key treatment decisions which could result in poor clinical and economic outcomes among kidney transplant recipients (KTRs). The burden of…
  • 2021 American Transplant Congress

    Systematic Evaluation of Immunosuppressant Drug Tolerability in Lung Transplant Recipients with Short Telomere Syndrome

    R. Patolia1, R. Guzy2, L. Potter1

    1Department of Pharmacy, University of Chicago Medicine, Chicago, IL, 2Department of Medicine, Division of Pulmonology, University of Chicago Medicine, Chicago, IL

    *Purpose: Lung transplant recipients with short telomere syndrome are at high risk of hematologic complications. Consequently, patients with short telomere syndrome may require more frequent…
  • 2021 American Transplant Congress

    Use of Granulocyte Colony Stimulating Factor After Lung Transplantation is Not Associated with Increased Likelihood of Acute Cellular Rejection

    S. Fredrick1, C. Iasella2, L. Sacha3, R. Rivosecchi3, M. Morrell3, P. Sanchez3, J. Pilewski3, M. Snyder3, J. McDyer3, C. Moore3

    1University of Rochester Medical Center, Rochester, NY, 2University of Pittsburgh School of Pharmacy, Pittsburgh, PA, 3University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The cause of neutropenia in lung transplant recipients is multifactorial, including medications, viral infections, and antecedent disease. Granulocyte colony-stimulating factor (G-CSF) is commonly used…
  • 2021 American Transplant Congress

    Evaluation of a Weight-Based Mycophenolate Mofetil Dosing Protocol for Kidney Transplant Maintenance Immunosuppression

    M. Mahoney1, E. Kincaide1, J. Nelson1, K. Klein1, R. Hall1, S. Bhayana2

    1University Health, San Antonio, Department of Pharmacotherapy and Pharmacy Services, The University of Texas at Austin, Pharmacotherapy Division, College of Pharmacy, San Antonio, TX, 2University Transplant Center, University Health, San Antonio, Department of Nephrology, The University of Texas Health Science Center at San Antonio, San Antonio, TX

    *Purpose: To evaluate the safety and efficacy of a weight-based mycophenolate mofetil (MMF) dosing protocol in adult kidney transplant recipients (KTR).*Methods: This single-center retrospective study…
  • 2021 American Transplant Congress

    Characteristics, Risk Factors, and Outcomes of Neutropenia for the First Year After Liver or Kidney Transplantation in Children

    C. Jarasvaraparn1, S. Choudhury2, C. Rusch2, K. Liss1, J. Stoll1, S. Hmiel3, S. Kulkarni1

    1Pediatric Gastroenterology, Washington University School in St Louis, Saint Louis, MO, 2Pediatric, Washington University School in St Louis, Saint Louis, MO, 3Pediatric Nephrology, Washington University School in St Louis, Saint Louis, MO

    *Purpose: Prior studies in adults have shown that approximately 20-38 % of subjects undergoing solid organ transplant develop neutropenia. In the current study, we characterized…
  • 2021 American Transplant Congress

    Risk Factors and Outcomes of Neutropenia in Kidney Transplant Recipients

    R. Avery1, J. Motter1, S. Sae-Tia2, N. Lu1, W. Cochran1, A. Massie1, D. Brennan1, F. Akinwande1, S. Shoham1, E. Kraus1, N. Alachkar1, S. Alasfar1, F. Naqvi1, F. Al Ammary1, K. Marr1, S. Mehta Steinke1, N. Desai1, O. Ezennia1, P. Plummer1, C. Durand1, W. Werbel1, M. Y. Kim1, D. Segev1, J. Garonzik Wang1, B. Trollinger1, L. Lees1, L. Toman1, S. Shulder3, K. Dzintars1, D. Ostrander1

    1Johns Hopkins, Baltimore, MD, 2Stony Brook University, Stony Brook, NY, 3University of Rochester, Rochester, NY

    *Purpose: Neutropenia is a common side effect of valganciclovir and may pose increased risk for post-transplant infections. Medications such as mycophenolate and infections such as…
  • 2021 American Transplant Congress

    Clinical Consequences in Patients Experiencing Leukopenia and Neutropenia After Solid Organ Transplant

    A. Diamond1, N. Diehl2, K. Hiryak3, K. Mortia1, J. Au1, C. Ruggia-Check1, H. Clauss4

    1Pharmacy, Temple University Hospital, Philadelphia, PA, 2Pharmacy, UPMC Pinnacle Health, Harrisburg, PA, 3Pharmacy, Temple University School of Pharmacy, Philadelphia, PA, 4Infectious Diseases, Temple University Hospital, Philadelphia, PA

    *Purpose: The incidence of leukopenia and neutropenia in solid organ transplant (SOT) recipients can be influenced by medications required after transplant for immunosuppression and infection…
  • 2021 American Transplant Congress

    Delayed Valganciclovir Initiation and the Incidence of Cytomegalovirus Infection in Liver Transplant Recipients

    S. Shaikh, P. Kawewat-Ho, Y. Genyk, L. Sher, J. Kahn, L. Rivera

    Keck Medical Center of USC, Los Angeles, CA

    *Purpose: Opportunistic infections remain a significant burden after liver transplantation, particularly cytomegalovirus (CMV) infection. With the use of valganciclovir (VGCV), the incidence of CMV infection…
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