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Articles tagged "Nephropathy"

  • 2017 American Transplant Congress

    Hepatitis B Virus Infection Is Associated with Recurrent Nephropathy After Kidney Transplantation.

    G. Chen, C. Wang, Z. Wu, C. Wang, J. Qiu, L. Chen.

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Background Hepatitis B virus(HBV) infection can cause HBV associated nephropathy, and is one of the major reasons for secondary nephropathy. We carried out a retrospective…
  • 2017 American Transplant Congress

    Full Dose Cyclosporine Permanently Reverses Uncontrolled BK Viremia That Is Refractory to Tacrolimus Minimization.

    A. Caero, M. Shah, D. McKay, J. Kerr, J. Joliat, E. Chatfield, R. Steiner.

    Medicine, UCSD School of Medicine, San Diego, CA

    Latent BK infection is benign and common in transplanted kidneys, but active infection causes viremia and kidney damage. Standard practice is to reduce tacrolimus (TAC)…
  • 2017 American Transplant Congress

    Risk Factors for Polyomavirus Infection After Renal Transplantation: Introduction of the Protective Effect of Peritoneal Dialysis.

    S. Hosseini-Moghaddam, Q. Xu, J. Kum, H. Alharbi, A. Jevnikar, M. John, G. Singh, S. Parsons, M. Edgar, P. Luke.

    Medicine, Western University, London Health Sciences Centre, London, ON, Canada

    Objective: To determine the roles of pre and post-transplant variables on the risk of BK virus infection after renal transplantation.Method: This study is a single-…
  • 2017 American Transplant Congress

    Contrast-Induced Acute Kidney Injury in Kidney Transplant Recipients: A Meta-Analysis.

    W. Cheungpasitporn,1 C. Thongprayoon,1 M. Mao,1 S. Mao,2 M. D'Costa,1 W. Kittanamongkolchai,1 K. Kashani.1

    1Nephrology and Hypertension, Mayo Clinic, Rochester, MN; 2Transplantation Surgery, Mayo Clinic, Rochester

    OBJECTIVE: To evaluate the incidence of contrast-induced acute kidney injury (CIAKI) in kidney transplant recipients.METHODS: A literature search was performed using MEDLINE, EMBASE, and the…
  • 2017 American Transplant Congress

    Utility of Electron Microscopy in Kidney Transplant Biopsies.

    J. Grodsky,1 R. Craver,1,2 I. Ashoor.2

    1LSUHSC, New Orleans, LA; 2Children's Hospital, New Orleans, LA

    Background: Banff 2013 criteria recommends performing ultra-structural studies with electron microscopy (EM) in most kidney transplant (KT) biopsies if the technology is available. We aimed…
  • 2016 American Transplant Congress

    Kidney Transplantation from Thin Basement Membrane Nephropathy Donor.

    C. Choi,1 A. Han,1 S.-Y. Kim,1 S. Cho,1 M.-J. Cho,1 C. Lee,1 S. Ahn,1 S.-K. Min,1 J. Ha,1 M. Park,2 S. Kim,3 I. Jung,1 S.-I. Min.1

    1Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Laboratory Medicine, Korea Organ Donation Agency, Seoul, Republic of Korea; 3Surgery, Myongji Hospital, Goyang, Gyeonggi-do, Republic of Korea.

    PurposeThin basement membrane nephropathy (TBMN) is the most common cause of persistent glomerular hematuria. Most individuals with TBMN shows benign course, but it is hard…
  • 2016 American Transplant Congress

    HCK Is a Potential Mediator of Renal Fibrosis.

    C. Wei,1 M. Menon,1 L. Li,2 Z. Yi,1 K. Keung,3 C. Woytovich,1 I. Greene,1 W. Zhang,1 J. He,1 B. Murphy.1

    1Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY; 2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY; 3Centre for Transplant and Renal Research, Westmead Millenium Institute, University of Sydney at Westmead Hospital, New South Wales, Australia.

    Background: Renal fibrosis is the consequence of excessive accumulation of extracellular matrix that occurs in patients with chronic kidney disease (CKD) and in kidney transplant…
  • 2016 American Transplant Congress

    Novel Nuclear Factor-κB Activation Inhibitor, Dehydroxymethylepoxyquinomicin, Prevents the Development of Chronic Cyclosporine Nephropathy in Rats.

    S. Morita,1 K. Shinoda,1 S. Tamaki,1 H. Kono,2 Y. Kanno,3 K. Umezawa,4 K. Nakagawa,2 M. Oya.1

    1Urology, Keio University School of Medicine, Tokyo, Japan; 2Urology, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba, Japan; 3Nephrology, Tokyo Medical University, Tokyo, Japan; 4Molecular Target Medicine Screening, Aichi Medical University, Nagakute, Aichi, Japan.

    Purpose:The nephrotoxicity of the calcineurin inhibitors including cyclosporine is a major problem in the kidney transplantation. We investigated the effect of a novel nuclear factor-κB…
  • 2016 American Transplant Congress

    Slipping Through the Cracks: Late Onset BK Viremia.

    J. Gandhi,1 M. Mackenzie,1 D. DeWolfe,2 F. Cardarelli,3 M. Pavlakis,3 C. Tan.1,4

    1Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; 2Division of Nephrology, BIDMC, Boston, MA; 3The Transplant Institute, BIDMC, Boston, MA; 4Division of Infectious Disease, BIDMC, Boston, MA.

    Introduction: Most studies indicate that viremia caused by BK virus (BKV), the step preceding BKV associated nephropathy (BKVN) in kidney transplant recipients (KTRs), occurs within…
  • 2016 American Transplant Congress

    Urinary CXCL9 Protein as Biomarker for BK Polyoma Viremia.

    N. Sarabu,1 R. El-Rifai,2 J. Augustine,1 A. Padiyar,1 A. Huml,1 T. Young,1 V. Rodriguez,1 D. Hricik.1

    1Division of Nephrology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH; 2Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Introduction: BK infection is common in kidney transplant patients and can result in accelerated loss of allografts. Management involves empiric lowering of immunosuppression, which can…
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