2018 American Transplant Congress
Factor Analysis (FA) of Renal Transplant Biopsy (KTxBx) Data Enables Objective Assessment of Risk for Subsequent Death Censored Graft Failure (DCGF)
We examined the impact of five axes of injury identified by FA in the KTxBx on the hazard for subsequent DCGF in two DeKAF cohorts.Methods:…2018 American Transplant Congress
Population-Based Modeling of Prototypes and Determinants of Allograft Function Trajectories after Kidney Transplantation: Implications for Patient Monitoring and Risk Stratification
Paris Transplant Group, Paris, France.
Background:Although the current gold standard of monitoring kidney allograft patients relies primarily on GFR assessment, little is known about long-term eGFR trajectories prototypes and their…2018 American Transplant Congress
Unique Gene Expression Signatures in Urine Distinguish BK Virus Nephropathy from Acute Rejection in Kidney Transplant Patients with Graft Dysfunction
Acute cellular rejection and BK virus nephropathy both cause deteriorating graft function that can lead to graft loss. Distinguishing the two conditions rapidly and accurately…2018 American Transplant Congress
Identification of Noninvasive and Mechanistically-Informative Biomarkers Predictive of Reversal of Acute Cellular Rejection (ACR) in Kidney Allografts
1University of Michigan, Ann Arbor, MI; 2Weill Cornell Medical College, New York City, NY.
Objective: We determined whether urinary cell mRNAs predict response to anti-rejection therapy in kidney allograft recipients with Banff grade IA or higher ACR biopsies.Methods: We…2018 American Transplant Congress
Meeting OPTN Requirements for Living Kidney Donation Follow-Up: Findings from the KDOC Study
The Organ Procurement and Transplantation Network (OPTN) requires programs to submit complete, accurate and timely clinical information for 80% and laboratory data for 70% of…2018 American Transplant Congress
Cold Pulsatile Machine Perfusion versus Static Cold Storage in Kidneys from Donation after Circulatory Death: A Multi-Centre Randomised Controlled Trial
Introduction:Delayed graft function affects around half of all recipients of donation after circulatory death (DCD) kidneys in the UK and has a significant impact on…2018 American Transplant Congress
Association of Body Mass Index of Kidney Transplant Recipients with Graft Function Post-Transplant
Henry Ford Transplant Institute, Detroit, MI.
Purpose: Obese kidney transplant recipients (KTR) are known to have a significantly higher risk of delayed graft function; however, there is no data on patients…2018 American Transplant Congress
Transplant Hospitals Increase Volumes and Acceptance Rates under the COIIN Project
United Network for Organ Sharing, Richmond.
Introduction. Transplant center performance monitoring is based on one-year patient and graft survival. Through the OPTN contract with HRSA, UNOS created the Collaborative Innovation and…2018 American Transplant Congress
Evaluating Transplant Quality Staffing Models via a National Survey
Vanderbilt Transplant Center, VUMC, Nashville, TN.
The 2007 CMS Final Rule included expectations that transplant centers implement data-driven quality assessment and performance improvement (QAPI) programs. Currently, insufficient data exists to guide…2018 American Transplant Congress
Everolimus with Reduced-Dose Calcineurin Inhibitor versus Mycophenolate with Standard-Dose Calcineurin Inhibitor in De Novo Kidney Transplant Recipients: Renal Function Results from the TRANSFORM Study
1TRANSFORM Study Group, Barcelona, Spain; 2Novartis Pharma AG, Basel, Switzerland.
Purpose: TRANSFORM (NCT01950819) is the largest study conducted in de novo kidney transplant recipients (KTxRs) to evaluate the benefit of everolimus with reduced-dose calcineurin inhibitor…
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