2022 American Transplant Congress
Delta Changes in Donor-Derived Cell-Free DNA (dd-cfDNA) Complement the Donor Fraction in Kidney Transplant Surveillance
*Purpose: Delta changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the…2022 American Transplant Congress
Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients
1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA
*Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…2022 American Transplant Congress
Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)
*Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…2022 American Transplant Congress
Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study
*Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…2022 American Transplant Congress
A Novel Prospective Validation Trial Of Multiple Blood-based RNA Signature Assays Pre And Post Kidney Transplant To Predict Rejection
*Purpose: The accuracy and utility of clinically defined and analytically validated predictive biomarkers in kidney transplantation is limited. We leveraged prior feasibility blood-RNA studies to…2022 American Transplant Congress
Outcomes of COVID-19 in Solid Organ Transplant Recipients in Canada 2020-2021: A Prospective, Multicenter Cohort Study
*Purpose: To understand the outcomes and changes in disease severity of COVID-19 in Solid Organ Transplant (SOT) recipients over time in the context of therapeutic…2022 American Transplant Congress
Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Practice Patterns, Report from the Paramour “Pediatric Renal AMR Outcomes” Study
*Purpose: There is insufficient data on children with AMR in the literature, and the optimal therapy for AMR is not well defined. We aim to…2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…2022 American Transplant Congress
BMI Trajectory and Attributable Risk of New Onset Hypertension Among Obese Living Kidney Donors
*Purpose: Obesity increases hypertension risk in general and living kidney donor populations. Risk attributable to donation in the context of obesity and whether that risk…2022 American Transplant Congress
Outcomes of SARS-CoV-2 Infection in Unvaccinated Compared with One or Two Dose Vaccinated Solid Organ Transplant Recipients: A Multicenter, Matched Cohort Study
*Purpose: It is unknown if vaccine breakthrough COVID-19 infections are milder or as severe as infections in unvaccinated solid organ transplant (SOT) recipients.*Methods: We performed…
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