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Articles tagged "Multicenter studies"

  • 2018 American Transplant Congress

    Meeting OPTN Requirements for Living Kidney Donation Follow-Up: Findings from the KDOC Study

    J. Rodrigue,1 C. Sokas,1 A. Fleishman,1 J. Schold,2 P. Morrissey,3 J. Whiting,4 J. Vella,4 L. Kayler,5 D. Katz,6 J. Jones,6 B. Kaplan,7 M. Pavlakis,1 D. Mandelbrot.8

    1Beth Israel Deaconess Medical Center, Boston; 2Cleveland Clinic, Cleveland; 3Rhode Island Hospital, Providence; 4Maine Medical Center, Portland; 5Erie County Medical Center, Buffalo; 6University of Iowa, Iowa City; 7Mayo Clinic, Scottsdale; 8University of Wisconsin, Madison.

    The Organ Procurement and Transplantation Network (OPTN) requires programs to submit complete, accurate and timely clinical information for 80% and laboratory data for 70% of…
  • 2018 American Transplant Congress

    Cold Pulsatile Machine Perfusion versus Static Cold Storage in Kidneys from Donation after Circulatory Death: A Multi-Centre Randomised Controlled Trial

    D. Summers,1,2 L. Randle,1 A-.M. O'Sullivan,3 R. Johnson,2 D. Collett,2 M. Attia,4 N. Ahmad,4 M. Clancy,5 M. Akyol,6 A. Tavakoli,7 N. Jamieson,3 A. Bradley,1 C. Watson.1

    1Cambridge University, Cambridge, United Kingdom; 2NHS Blood and Transplant, Bristol, United Kingdom; 3Cambridge University Hospitals, Cambridge, United Kingdom; 4Leeds Teaching Hospitals, Leeds, United Kingdom; 5Queen Elizabeth Hospital, Glasgow, United Kingdom; 6Edinburgh University, Edinburgh, United Kingdom; 7Manchester University Hospitals, Manchester, United Kingdom.

    Introduction:Delayed graft function affects around half of all recipients of donation after circulatory death (DCD) kidneys in the UK and has a significant impact on…
  • 2018 American Transplant Congress

    Association of Body Mass Index of Kidney Transplant Recipients with Graft Function Post-Transplant

    A. Yaldo, I. Bajjoka, C. Crombez, M. Abouljoud.

    Henry Ford Transplant Institute, Detroit, MI.

    Purpose: Obese kidney transplant recipients (KTR) are known to have a significantly higher risk of delayed graft function; however, there is no data on patients…
  • 2018 American Transplant Congress

    Transplant Hospitals Increase Volumes and Acceptance Rates under the COIIN Project

    D. Klassen, H. Haskell, K. Sisaithong, M. McBride, R. Carrico, M. Curry.

    United Network for Organ Sharing, Richmond.

    Introduction. Transplant center performance monitoring is based on one-year patient and graft survival. Through the OPTN contract with HRSA, UNOS created the Collaborative Innovation and…
  • 2018 American Transplant Congress

    Evaluating Transplant Quality Staffing Models via a National Survey

    M. Cook, I. Feurer, L. Smith, S. Rega, E. Zavala.

    Vanderbilt Transplant Center, VUMC, Nashville, TN.

    The 2007 CMS Final Rule included expectations that transplant centers implement data-driven quality assessment and performance improvement (QAPI) programs. Currently, insufficient data exists to guide…
  • 2018 American Transplant Congress

    Everolimus with Reduced-Dose Calcineurin Inhibitor versus Mycophenolate with Standard-Dose Calcineurin Inhibitor in De Novo Kidney Transplant Recipients: Renal Function Results from the TRANSFORM Study

    F. Oppenheimer,1 C. Legendre,1 J. Cruzado,1 G. Russ,1 O. Viklicky,1 R. Oberbauer,1 V. Garcia,1 O. Witzke,1 D. Kuypers,1 R. Danguilan,1 P. Bernhardt,2 C. Sommerer.1

    1TRANSFORM Study Group, Barcelona, Spain; 2Novartis Pharma AG, Basel, Switzerland.

    Purpose: TRANSFORM (NCT01950819) is the largest study conducted in de novo kidney transplant recipients (KTxRs) to evaluate the benefit of everolimus with reduced-dose calcineurin inhibitor…
  • 2018 American Transplant Congress

    Components of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBX) Impacting Late Death Censored Graft Failure (DCGF)

    J. Grande,1 L. Hunsicker,2 R. LeDuc,3 A. Matas,3 The DeKAF Consortium.

    1Pathology, Mayo Clinic, Rochester, MN; 2Int. Med., U Iowa, Iowa City, IA; 3Biostatistics and Surgery, U Minnesota, Minneapolis, MN.

    Recent studies document that MVI increases DCGF. However, the relationship between components of MVI (Banff scores g, cg, ptc) and macrovascular inflammation (v) have not…
  • 2018 American Transplant Congress

    Higher Early Post-Liver Transplant Mortality in Recipients with Severe Alcoholic Hepatitis versus Alcoholic Cirrhosis

    B. Lee, G. Im, J. Dodge, M. Voigt, J. Rice, M. Lucey, D. Foley, L. Platt, A. Gurakar, N. Mehta, G. Therapondos, H. Han, D. Victor, O. Fix, L. Dinges, D. Dronamraju, C. Hsu, M. Rinella, H. Maddur, S. Eswaran, J. Hause, R. Ghobrial, Z. Li, N. Terrault.

    UCSF, SF; Mt Sinai, NYC; Iowa, Iowa; UW, Madison; Hopkins, Baltimore; Ochsner, Jefferson; USC, LA; Houston Methodist, Houston; Swedish, Seattle; Maryland, Baltimore; UPenn, Philadelphia; NW, Chicago; Rush, Chicago.

    INTRODUCTIONThe American Consortium of Early Liver Transplantation for Alcoholic Hepatitis (ACCELERATE-AH) is a multicenter cohort from 8 UNOS regions studying early liver transplant (LT) for…
  • 2018 American Transplant Congress

    The Chauvet Workgroup: From Inception to the Future

    H. Amer,1 S. Jowsey-Gregoire,1 M. Kumnig,2 E. Moreno,3 W. Dean,4 C. Brown,5 S. Jarvholm,6 K. Coffman,7 P. Petruzzo,8 E. Morelon.8

    1Mayo Clinic, Rochester, MN; 2University of Innsbruck, Innsbruck, Austria; 3UCLA, Los Angeles, CA; 4US Department of Defense, Fort Detrick, MD; 5University of Pittsburgh, Pittsburgh, PA; 6University of Gothenburg, Gothenburg, Sweden; 7Cleveland Clinic, Cleveland, OH; 8University of Lyon, Lyon, France.

    From the first hand transplant that ushered in the era of reconstructive transplantation, it was apparent that the psychosocial background of the patient and the…
  • 2018 American Transplant Congress

    Molecular Phenotypes of Injury and Rejection in Lung Transplant Transbronchial Biopsies

    M. Parkes, K. Halloran, K. Famulski, P. Halloran, The INTERLUNG Study Group.

    University of Alberta, Edmonton, Canada.

    Purpose: Histologic assessment of lung transplant transbronchial biopsies (TBB) is not reproducible and cannot assess antibody-mediated rejection (ABMR). Molecular diagnostics (MMDx) successfully identified rejection in…
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