2018 American Transplant Congress
Evaluating Transplant Quality Staffing Models via a National Survey
Vanderbilt Transplant Center, VUMC, Nashville, TN.
The 2007 CMS Final Rule included expectations that transplant centers implement data-driven quality assessment and performance improvement (QAPI) programs. Currently, insufficient data exists to guide…2018 American Transplant Congress
Everolimus with Reduced-Dose Calcineurin Inhibitor versus Mycophenolate with Standard-Dose Calcineurin Inhibitor in De Novo Kidney Transplant Recipients: Renal Function Results from the TRANSFORM Study
1TRANSFORM Study Group, Barcelona, Spain; 2Novartis Pharma AG, Basel, Switzerland.
Purpose: TRANSFORM (NCT01950819) is the largest study conducted in de novo kidney transplant recipients (KTxRs) to evaluate the benefit of everolimus with reduced-dose calcineurin inhibitor…2018 American Transplant Congress
Components of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBX) Impacting Late Death Censored Graft Failure (DCGF)
Recent studies document that MVI increases DCGF. However, the relationship between components of MVI (Banff scores g, cg, ptc) and macrovascular inflammation (v) have not…2018 American Transplant Congress
Higher Early Post-Liver Transplant Mortality in Recipients with Severe Alcoholic Hepatitis versus Alcoholic Cirrhosis
INTRODUCTIONThe American Consortium of Early Liver Transplantation for Alcoholic Hepatitis (ACCELERATE-AH) is a multicenter cohort from 8 UNOS regions studying early liver transplant (LT) for…2018 American Transplant Congress
The Chauvet Workgroup: From Inception to the Future
From the first hand transplant that ushered in the era of reconstructive transplantation, it was apparent that the psychosocial background of the patient and the…2018 American Transplant Congress
Molecular Phenotypes of Injury and Rejection in Lung Transplant Transbronchial Biopsies
University of Alberta, Edmonton, Canada.
Purpose: Histologic assessment of lung transplant transbronchial biopsies (TBB) is not reproducible and cannot assess antibody-mediated rejection (ABMR). Molecular diagnostics (MMDx) successfully identified rejection in…2018 American Transplant Congress
Death-Censored Graft Failure (DCGF) Post Kidney Transplant (KTx) is Usually the Result of Rapid Loss of Function after Periods of Stability
Late graft dysfunction leading to clinically indicated transplant biopsy (KTxBx) is a better predictor of subsequent DCGF than baseline data and early post-transplant events (Gaston…2018 American Transplant Congress
T Cell-Mediated Rejection Poses Greater Risk to Graft Survival Than Antibody-Mediated Rejection in Heart Transplants
University of Alberta, Edmonton, Canada.
Purpose: In kidney transplants, failure post-biopsy is associated with acute injury transcript expression reflecting the histologically silent tissue response-to-wounding (JCI 120:1862) and antibody-mediated rejection (ABMR),…2018 American Transplant Congress
Livers from Diabetic Donors Can Safely Be Used in Donation after Circulatory Death Liver Transplantation
Liver grafts from donors with a history of diabetes mellitus (DM) have been associated with reduced graft survival after liver transplantation. Transplantation centers are often…2018 American Transplant Congress
Direct-Acting Antiviral Therapy Immune-Mediated Graft Dysfunction in Liver Transplant Recipients with Hepatitis C
Background and Aims:Interferon (IFN) treatment of hepatitis C virus (HCV) infection after liver transplantation (LT) can result in severe immune-mediated graft dysfunction (IGD). The occurrence…
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