Articles tagged "Multicenter studies"

2020 American Transplant Congress
History of Coronary Artery Disease Predicts Inferior Survival in Liver Transplant Recipients of Advanced Age in a Large Multicenter U.S. Cohort
M. German¹, A. Hristov¹, A. Lee¹, F. Osman¹, A. Kwong², D. Devuni³, C. Wang⁴, J. Boike⁵, J. Jo⁵, L. VanWagner⁵, M. Serper⁶, R. Sharma⁷, E. Verna⁷, J. Shor³, A. Koteish⁸, G. Sehmbey⁹, A. Seetharam⁹, N. John², Y. Patel¹⁰, M. Kappus¹⁰, T. Couri¹¹, S. Paul¹¹, R. Salgia¹², Q. Nhu¹³, C. Frenette¹³, J. Lai⁴, A. Goel², E. Spengler¹
¹U of Wisconsin, Madison, WI, ²Stanford, Palo Alto, CA, ³U of Massachusetts, Worcester, MA, ⁴U of California, San Francisco, CA, ⁵Northwestern, Chicago, IL, ⁶U of Pennsylvania, Philadelphia, PA, ⁷Columbia, New York, NY, ⁸Florida Hospital, Orlando, FL, ⁹U of Arizona, Phoenix, AZ, ¹⁰Duke, Durham, NC, ¹¹U of Chicago, Chicago, IL, ¹²Henry Ford Hospital, Detroit, MI, ¹³Scripps, San Diego, CA
*Purpose: Coronary artery disease (CAD) is common in patients of advanced age and does not preclude liver transplantation (LT) if adequately treated. We aimed to…
2020 American Transplant Congress
Re-Establishing Abstinence after Alcohol Relapse after Early Transplant (LT) for Alcoholic Hepatitis (AH) Provides Survival Advantage
J. Rice¹, B. Lee², G. Therapondos³, G. Im⁴, A. Lazar², M. Lucey¹, E. Weinberg⁵, H. Han⁶, H. Maddur⁷, M. Ghobrial⁸, C. Hsu⁹, O. Fix¹⁰, S. Eswaran¹¹, K. Shetty¹², N. Jakhete¹², D. Victor⁸, D. Foley¹, N. Mehta², M. Rinella⁷, T. Schiano⁴, C. Mobley⁸, N. Terrault⁶
¹U of WI SMPH, Madison, WI, ²UCSF, San Francisco, CA, ³Oschner, New Orleans, LA, ⁴Mt Sinai, New York, NY, ⁵U Penn, Philadelphia, PA, ⁶USC, Los Angeles, CA, ⁷NW Univ, Chicago, IL, ⁸Houston Mdt, Houston, TX, ⁹GTown U, Washington, DC, ¹⁰Swed Med, Seattle, WA, ¹¹Rush Med C, Chicago, IL, ¹²U of MD, Baltimore, MD
*Purpose: Among the ACCELERATE-AH cohort: (i) Identify factors associated with re-established abstinence in patients with alcohol relapse after LT for alcoholic hepatitis (AH); (ii) Determine…
2020 American Transplant Congress
MELD is MELD is MELD? Geographic/ Center-Level Variation in Mortality for Patients with the Same MELD Score
T. Ishaque¹, A. B. Massie¹, A. B. Kernodle¹, S. Getsin¹, P. Chaing¹, J. G. Jacqueline Garonzik Wang¹, S. Gentry², D. Segev¹
¹Johns Hopkins University, Baltimore, MD, ²Department of Mathematics, United States Naval Academy, Annapolis, MD
*Purpose: Waitlist candidates living in areas with poor access to health care may have higher mortality risk compared to candidates with same MELD in other…
2020 American Transplant Congress
Frailty Prior to Hospital Discharge Predicts Mortality after Cirrhosis-Related Admissions
M. Serper¹, S. Tao², P. Garren¹, D. Peyton¹, M. A. Dunn², K. Reddy¹, A. Gougol², A. Duarte-Rojo²
¹University of Pennsylvania, Philadelphia, PA, ²University of Pittsburgh, Pittsburgh, PA
*Purpose: Inpatient frailty assessment and its utility in clinical care is understudied in liver transplant (LT) candidates. Study objectives were to quantify physical frailty among…
2020 American Transplant Congress
A Multicenter Analysis of the Proportion and Pattern of Unexplained HLA Antibodies in Kidney Recipients without a History of Sensitization
J. Lan¹, J. S. Gill¹, H. M. Gebel², R. A. Bray², R. Liwski³, A. Vinson⁴, A. Greenshields³, S. Dobrer⁵, O. Gunther⁵, K. Sherwood⁵, F. H. Claas⁶, S. Heidt⁶, G. Karahan⁶, J. Gill⁷, M. Gill¹, U. Varyani¹, P. Jindal¹, P. Keown⁵
¹Medicine, Division of Nephrology, University of British Columbia, Vancouver, BC, Canada, ²Pathology, Emory University, Atlanta, GA, ³Pathology, Dalhousie University, Halifax, NS, Canada, ⁴Nephrology, Dalhousie University, Halifax, NS, Canada, ⁵Pathology, University of British Columbia, Vancouver, BC, Canada, ⁶Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands, ⁷Nephrology, Emory University, Atlanta, GA
*Purpose: Previous studies report a high prevalence of unexplained antibody reactivities on the single antigen bead (SAB) test. In a contemporary multicenter cohort of non-sensitized…
2020 American Transplant Congress
Integrated Multicohort Analysis of Transcriptome Profiles Identifies Blood Gene Signature to Distinguish Rejection from Infection in Patients with Solid Organ Transplants
L. C. Murphy, A. Rao, M. Donato, P. Khatri
School of Medicine, Stanford University, Stanford, CA
*Purpose: Allograft rejection and infection are now leading causes of morbidity and mortality in transplant recipients. Current diagnosis relies on nonspecific markers of graft injury,…
2019 American Transplant Congress
Unique Gene Expression Signatures in Urine Distinguish T Cell Mediated Acute Rejection from BK Virus Nephropathy in Kidney Transplant Patients
K. S. Keslar¹, W. Xu², A. A. Zmijewska³, K. A. Newell⁴, J. J. Friedewald⁵, M. I. Abecassis⁵, P. S. Heeger⁶, J. S. Bromberg⁷, R. B. Mannon³, R. L. Fairchild¹
¹Cleveland Clinic, Cleveland, OH, ²Nanostring Technologies, Seattle, WA, ³Univ. Alabama Birmingham, Birmingham, AL, ⁴Emory Univ., Atlanta, GA, ⁵Northwestern Univ., Chicago, IL, ⁶Icahn School of Med., New York, NY, ⁷Univ. Maryland, Baltimore, MD
*Purpose: There is a need to develop non-invasive approaches to detect ongoing kidney graft injury and distinguish immune from non-immune inflammation to guide therapy. Ideally…
2019 American Transplant Congress
Access To The Kidney Transplant Waitlist For Patients With Hiv And End-stage Renal Disease
A. A. Shaffer¹, H. Ying², N. Chu¹, A. G. Thomas³, C. Haugen², S. Norman⁴, D. L. Segev¹, M. A. McAdams-DeMarco¹
¹Surgery & Epidemiology, Johns Hopkins University, Baltimore, MD, ²Surgery, Johns Hopkins University, Baltimore, MD, ³Epidemiology, University of North Carolina, Chapel Hill, NC, ⁴Surgery, University of Michigan, Ann Arbor, MI
*Purpose: Patients with HIV and end-stage renal disease (ESRD) experience higher mortality on dialysis than those without HIV. These HIV+ dialysis patients may face barriers…
2019 American Transplant Congress
Donor Safety for Minimal Invasive Hepatectoy in Liver Transplantation: The Korean Organ Transplantation Registry
H. Yu, J. Yang, S. Ahn
Chonbuk National University Hospital, Jeonju, Korea, Republic of
*Purpose: This study evaluated the safety and effectiveness of minimal invasive living donor hepatectomy in comparison with conventional open procedure using Korean Organ Transplantation Registry…
2019 American Transplant Congress
Deceased-Donor Acute Kidney Injury Associates with Less BK Viremia in Kidney Transplant Recipients
I. E. Hall, P. P. Reese, S. G. Mansour, S. Mohan, M. D. Doshi, Y. Jia, H. R. Thiessen-Philbrook, E. Akalin, M. N. Harhay, T. Muthukumar, B. Schröppel, P. Singh, F. L. Weng, J. S. Bromberg, C. R. Parikh
For the DDS Consortium, Baltimore, MD
*Purpose: BK viremia (BKV) and polyomavirus nephropathy are kidney transplant complications that contribute to morbidity and graft loss, and prior studies suggest they may be…

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