Articles tagged "Multicenter studies"

2021 American Transplant Congress
Covid-19 Caseload and Management Practices Vary by Program-Level Factors: A Multinational Survey Study
S. Sandal¹, B. Boyarsky², P. Chiang², A. Massie², D. Segev², M. Cantarovich¹
¹McGill University, Montreal, QC, Canada, ²Johns Hopkins University, Baltimore, MD
*Purpose: During the pandemic, the COVID-19 patient caseload (CPC) is thought to be highly variable and likely dependant on the cumulative COVID-19 incidence (CCI) of…
2021 American Transplant Congress
SARS-CoV-2 Infection Among Kidney Transplant Recipients: A Multicenter Brazilian Cohort Study
T. Sandes-Freitas¹, J. Medina-Pestana², o. COVID-19 Brazil Study Group³
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Hospital do Rim, São Paulo, Brazil, ³Brazil, Brazil, Brazil
*Purpose: Limited data are available on COVID-19 clinical presentation and outcomes among kidney transplant (KT) recipients.*Methods: Multicenter Brazilian cohort of KT patients with laboratory-confirmed SARS-CoV-2…
2021 American Transplant Congress
Early Detection of SARS-CoV-2 and Other Infections in Solid Organ Transplant Recipients and Household Members Using Wearable Devices
E. H. Li¹, E. Mukhtar¹, E. D. Elftmann¹, F. R. Eweje¹, H. Gao¹, L. I. Ibrahim¹, R. G. Kathawate¹, A. C. Lee¹, K. A. Moore¹, N. Nair¹, S. Amaral², M. Snyder³, B. J. Keating¹
¹Department of Surgery, Penn Transplant Institute, Division of Transplantation, Philadelphia, PA, ²Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Genetics, Stanford University, Palo Alto, CA
*Purpose: Wearable devices that measure physiological parameters have shown utility for detecting infections such as influenza and recently COVID-19 up to 10 days before clinical…
2021 American Transplant Congress
Outcomes of Downstaging Hepatocellular Carcinoma (HCC) to within Milan Criteria Before Liver Transplantation (LT): A Multicenter Analysis of the “All-comers” Protocol
B. Natarajan¹, P. Tabrizian², M. Hoteit³, C. Frenette⁴, T. Ghaziani⁵, R. Dhanasekaran⁵, N. Parikh⁶, J. Guy⁷, A. Shui¹, S. Florman², F. Yao¹, N. Mehta¹
¹UCSF, SF, CA, ²Mt Sinai, NY, NY, ³U Penn, Philadelphia, PA, ⁴Scripps, La Jolla, CA, ⁵Stanford, Palo Alto, CA, ⁶U Michigan, Ann Arbor, MI, ⁷CPMC, SF, CA
*Purpose: Patients with HCC meeting UNOS-downstaging (DS) criteria (1 lesion 5.1-8 cm, 2-3 lesions at least one 3.1-5 cm and total tumor diameter (TTD) ≤8…
2021 American Transplant Congress
Trends in Mortality Among Solid Organ Transplant Recipients Hospitalized for Covid-19 During the Course of the Pandemic
M. R. Heldman, O. S. Kates, R. M. Rakita, E. D. Lease, C. E. Fisher, A. P. Limaye
University of Washington, Seattle, WA
*Purpose: Actual and comorbidity-adjusted mortality in hospitalized patients with COVID-19 has declined in the general population during the course of the pandemic. Whether a similar…
2020 American Transplant Congress
Automated Monitoring of Four Urinary Biomarkers in Routine Surveillance Identifies Patients at Low and High Risk of Renal Allograft Injury
L. Sheward¹, J. Wedel¹, N. Rodig¹, R. Mannon², O. Bestard³, V. Dharnidharka⁴, D. Zurakowski¹, A. Kho¹, T. Blydt-Hansen⁵, M. Seifert², D. M. Briscoe¹
¹Boston Children's Hospital, Boston, MA, ²University of Alabama at Birmingham, Birmingham, AL, ³Bellvitge University Hospital, Barcelona, Spain, ⁴St Louis Children's Hospital, St Louis, MO, ⁵BC Children's Hospital, Vancouver, BC, Canada
*Purpose: Surveillance renal biopsy data indicate that up to 36% of clinically stable kidney allograft recipients have subclinical rejection, emphasizing the need to implement automated…
2020 American Transplant Congress
Impact of Extended- versus Immediate-Release Tacrolimus on One-Year Development of De Novo DSA and Chronic Immune Activation in Kidney Transplantation (ASTOUND Study)
A. Wiseman¹, D. Kaufman², A. Patel³, D. Wojciechowski⁴, A. Tambur⁵, J. Kim⁶, J. Schwartz⁶
¹University of Colorado Hospital, Aurora, CO, ²University of Wisconsin, Madison, WI, ³Henry Ford Hospital, Detroit, MS, ⁴Massachusetts General Hospital, Boston, MA, ⁵Northwestern University, Chicago, IL, ⁶Astellas Pharma Global Development, Northbrook, IL
*Purpose: To compare, using an adaptive study design, the 1-year incidence of a novel two-part composite endpoint consisting of de novo donor-specific antibody (dnDSA) formation…
2020 American Transplant Congress
History of Coronary Artery Disease Predicts Inferior Survival in Liver Transplant Recipients of Advanced Age in a Large Multicenter U.S. Cohort
M. German¹, A. Hristov¹, A. Lee¹, F. Osman¹, A. Kwong², D. Devuni³, C. Wang⁴, J. Boike⁵, J. Jo⁵, L. VanWagner⁵, M. Serper⁶, R. Sharma⁷, E. Verna⁷, J. Shor³, A. Koteish⁸, G. Sehmbey⁹, A. Seetharam⁹, N. John², Y. Patel¹⁰, M. Kappus¹⁰, T. Couri¹¹, S. Paul¹¹, R. Salgia¹², Q. Nhu¹³, C. Frenette¹³, J. Lai⁴, A. Goel², E. Spengler¹
¹U of Wisconsin, Madison, WI, ²Stanford, Palo Alto, CA, ³U of Massachusetts, Worcester, MA, ⁴U of California, San Francisco, CA, ⁵Northwestern, Chicago, IL, ⁶U of Pennsylvania, Philadelphia, PA, ⁷Columbia, New York, NY, ⁸Florida Hospital, Orlando, FL, ⁹U of Arizona, Phoenix, AZ, ¹⁰Duke, Durham, NC, ¹¹U of Chicago, Chicago, IL, ¹²Henry Ford Hospital, Detroit, MI, ¹³Scripps, San Diego, CA
*Purpose: Coronary artery disease (CAD) is common in patients of advanced age and does not preclude liver transplantation (LT) if adequately treated. We aimed to…
2020 American Transplant Congress
Re-Establishing Abstinence after Alcohol Relapse after Early Transplant (LT) for Alcoholic Hepatitis (AH) Provides Survival Advantage
J. Rice¹, B. Lee², G. Therapondos³, G. Im⁴, A. Lazar², M. Lucey¹, E. Weinberg⁵, H. Han⁶, H. Maddur⁷, M. Ghobrial⁸, C. Hsu⁹, O. Fix¹⁰, S. Eswaran¹¹, K. Shetty¹², N. Jakhete¹², D. Victor⁸, D. Foley¹, N. Mehta², M. Rinella⁷, T. Schiano⁴, C. Mobley⁸, N. Terrault⁶
¹U of WI SMPH, Madison, WI, ²UCSF, San Francisco, CA, ³Oschner, New Orleans, LA, ⁴Mt Sinai, New York, NY, ⁵U Penn, Philadelphia, PA, ⁶USC, Los Angeles, CA, ⁷NW Univ, Chicago, IL, ⁸Houston Mdt, Houston, TX, ⁹GTown U, Washington, DC, ¹⁰Swed Med, Seattle, WA, ¹¹Rush Med C, Chicago, IL, ¹²U of MD, Baltimore, MD
*Purpose: Among the ACCELERATE-AH cohort: (i) Identify factors associated with re-established abstinence in patients with alcohol relapse after LT for alcoholic hepatitis (AH); (ii) Determine…
2020 American Transplant Congress
MELD is MELD is MELD? Geographic/ Center-Level Variation in Mortality for Patients with the Same MELD Score
T. Ishaque¹, A. B. Massie¹, A. B. Kernodle¹, S. Getsin¹, P. Chaing¹, J. G. Jacqueline Garonzik Wang¹, S. Gentry², D. Segev¹
¹Johns Hopkins University, Baltimore, MD, ²Department of Mathematics, United States Naval Academy, Annapolis, MD
*Purpose: Waitlist candidates living in areas with poor access to health care may have higher mortality risk compared to candidates with same MELD in other…