Articles tagged "Multicenter studies"

2021 American Transplant Congress
The Impact of the Covid-19 Pandemic on Measures of Transplant Activity is Higher in Lower-Income Countries: A Multinational Survey Study
S. Sandal¹, B. Boyarsky², P. Chiang², A. Massie², D. Segev², M. Cantarovich¹
¹McGill University, Montreal, QC, Canada, ²Johns Hopkins University, Baltimore, MD
*Purpose: The COVID-19 pandemic has affected the field of solid organ transplantation due to the “ramp-down” of activity during the initial months. Impact on transplant…
2021 American Transplant Congress
Posttraumatic Stress and Medication Adherence in Pediatric Transplant Recipients
S. Duncan-Park¹, L. Danziger-Isakov², B. Armstrong³, N. Williams⁴, J. Odim⁴, E. Shemesh⁵, S. Sweet⁶, R. Annunziato¹
¹Icahn School of Medicine at Mount Sinai and Fordham University, New York, NY, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Rho Inc., Durham, NC, ⁴NIAID, Bethesda, MD, ⁵Icahn School of Medicine at Mount Sinai, New York, NY, ⁶Washington University in St. Louis, St. Louis, MO
*Purpose: We investigated the relationship between posttraumatic stress symptoms (PTSS), medication adherence, and quality of life (QoL) in adolescent transplant recipients.*Methods: This protocol of the…
2021 American Transplant Congress
Simultaneous Heart-Liver-Kidney Transplantation Survival: National and Single-Center Outcomes
U. A. Siddiqi¹, P. S. Combs¹, G. Kim², T. Baker³, Y. Becker¹, V. Jeevanandam¹
¹Section of Cardiac Surgery, University of Chicago Medicine, Chicago, IL, ²Section of Cardiology, University of Chicago Medicine, Chicago, IL, ³University of Chicago Medicine, Chicago, IL
*Purpose: Simultaneous Heart-Liver-Kidney transplantation (SHLKTx) is an incredibly rare, high-risk operation undergone by well-selected patients presenting with multi-organ failure. Our center has performed 10 of…
2021 American Transplant Congress
Covid-19 Caseload and Management Practices Vary by Program-Level Factors: A Multinational Survey Study
S. Sandal¹, B. Boyarsky², P. Chiang², A. Massie², D. Segev², M. Cantarovich¹
¹McGill University, Montreal, QC, Canada, ²Johns Hopkins University, Baltimore, MD
*Purpose: During the pandemic, the COVID-19 patient caseload (CPC) is thought to be highly variable and likely dependant on the cumulative COVID-19 incidence (CCI) of…
2021 American Transplant Congress
SARS-CoV-2 Infection Among Kidney Transplant Recipients: A Multicenter Brazilian Cohort Study
T. Sandes-Freitas¹, J. Medina-Pestana², o. COVID-19 Brazil Study Group³
¹Universidade Federal do Ceará, Fortaleza, Brazil, ²Hospital do Rim, São Paulo, Brazil, ³Brazil, Brazil, Brazil
*Purpose: Limited data are available on COVID-19 clinical presentation and outcomes among kidney transplant (KT) recipients.*Methods: Multicenter Brazilian cohort of KT patients with laboratory-confirmed SARS-CoV-2…
2020 American Transplant Congress
Evolution of Molecular Lung Transplant Biopsy Assessment: Rejection Can be Detected in Mucosal as Well as Transbronchial Biopsies
M. D. Parkes¹, K. Halloran², P. Halloran², &. the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: We recently developed a Molecular Microscope® (MMDx) rejection assessment platform for mucosal biopsies from the third airway bifurcation (3BMB) and transbronchial biopsies (TBB) from…
2020 American Transplant Congress
Atrial Fibrillation Predicts Inferior Survival in Liver Transplant Recipients of Advanced Age in a Large Multicenter U.S. Cohort
M. German¹, A. Hristov¹, A. Lee¹, F. Osman¹, A. Kwong², D. Devuni³, C. Wang⁴, J. Boike⁵, J. Jo⁵, L. VanWagner⁵, M. Serper⁶, R. Sharma⁷, E. Verna⁷, J. Shor³, A. Koteish⁸, G. Sehmbey⁹, A. Seetharam⁹, N. John², Y. Patel¹⁰, M. Kappus¹⁰, T. Couri¹¹, S. Paul¹¹, R. Salgia¹², Q. Nhu¹³, C. Frenette¹³, J. Lai⁴, A. Goel², E. Spengler¹
¹U of Wisconsin, Madison, WI, ²Stanford, Palo Alto, CA, ³U of Massachusetts, Worcester, MA, ⁴U of California, San Francisco, CA, ⁵Northwestern, Chicago, IL, ⁶U of Pennsylvania, Philadelphia, PA, ⁷Columbia, New York, NY, ⁸Florida Hospital, Orlando, FL, ⁹U of Arizona, Phoenix, AZ, ¹⁰Duke, Durham, NC, ¹¹U of Chicago, Chicago, IL, ¹²Henry Ford Hospital, Detroit, MI, ¹³Scripps, San Diego, CA
*Purpose: More liver transplants (LT) are being performed in patients >65 years (y) - a population with higher rates of cardiovascular (CV) disease. It is…
2020 American Transplant Congress
Transarterial Chemoembolization and Radio-Embolization are Similarly Efficacious in Achieving Successful Hepatocellular Carcinoma (HCC) Down-Staging: Results from the Multicenter Evaluation of Reduction in Tumor Size Before Liver Transplantation (MERITS-LT) Consortium
N. Mehta¹, J. Guy², C. Frenette³, P. Tabrizian⁴, M. Hoteit⁵, N. Parikh⁶, T. Ghaziani⁷, R. Dhanasekaran⁷, J. L. Dodge¹, M. L. Holzner⁴, S. Florman⁴, F. Yao¹
¹UCSF, SF, CA, ²CPMC, SF, CA, ³Scripps Hospital, La Jolla, CA, ⁴Mt Sinai, NY, NY, ⁵U. Pennsylvania, Philadelphia, PA, ⁶U. Michigan, Ann Arbor, MI, ⁷Stanford, Palo Alto, CA
*Purpose: United Network of Organ Sharing (UNOS) Region 5 has reported excellent liver transplantation (LT) outcomes after successful down-staging (DS) in HCC patients exceeding Milan…
2020 American Transplant Congress
Reactivation of BK Polyomavirus after Kidney Transplantation: A Multi-Center Collaboration Examining the Impact of Adherence to a Screening Protocol on Clinical Outcomes
R. Rogers¹, F. Cheema², M. Chobanian³, Z. Ebcioglu², H. Gilligan⁴, R. Gohh¹, N. Goyal⁵, M. Pavlakis⁶, N. Rodig⁷, A. Rossi⁸, J. Singh², C. S. Tan⁶
¹Warren Alpert Medical School of Brown University, Providence, RI, ²Hartford Hospital, Hartford, CT, ³Geisel School of Medicine at Dartmouth, Hanover, NH, ⁴Massachusetts General Hospital, Boston, MA, ⁵Tufts University School of Medicine, Boston, MA, ⁶Beth Israel Deaconess Medical Center, Boston, MA, ⁷Boston Children's Hospital, Boston, MA, ⁸Maine Medical Center, Portland, ME
*Purpose: Reactivation of BK polyomavirus (BK) after kidney transplantation (KT) is common and can lead to adverse clinical outcomes such as allograft nephropathy (BKAN). In…
2020 American Transplant Congress
TRANSBIO Study: Clinical Evaluation of Immunobiogram, a Novel In Vitro Diagnostic Immunoassay to Guide Adjustment of Immunosuppressive Therapy in Kidney Transplantation
J. Pascual¹, C. Jiménez², M. Krajewska³, C. Kotton⁴, D. Seron⁵, J. Portolés⁶, O. Witzke⁷, S. S. Sorensen⁸, A. Andrés⁹, T. Díez¹⁰, A. Ortega¹⁰, I. Portero¹⁰
¹Consorci Mar Parc de Salut, Barcelona, Spain, ²La Paz Hospital, Madrid, Spain, ³Wroclaw Medical University, Wroclaw, Poland, ⁴Massachusetts General Hospital, Boston, MA, ⁵Vall d’Hebron Hospital, Barcelona, Spain, ⁶Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, ⁷University Hospital Essen, University Duisburg-Essen, Essen, Germany, ⁸Rigshospitalet, Copenhagen, Denmark, ⁹12 de Octubre Hospital, Madrid, Spain, ¹⁰Biohope Scientific Solutions for Human Health SL, Madrid, Spain
*Purpose: Immunobiogram (IMBG) is a first-in-class blood-based pharmacodynamic immunoassay that provides the sensitivity/resistance profile of each patient’s lymphocytes to a panel of immunosuppressive drugs (IS).…