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American Transplant Congress abstracts

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Articles tagged "Multicenter studies"

  • 2022 American Transplant Congress

    Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)

    D. J. Reich1, A. Schlegel2, M. Rizzari3, D. Foley4, M. DeVera5, W. Chapman6, G. Roll7, A. Saharia8, C. Quintini9, S. Florman10, S. Merani11, S. Mao12, A. Pinna13, M. Akoad14, C. Kubal15, S. Alexopoulos16, H. Bohorquez17

    1Drexel University, Philadelphia, PA, 2Careggi U, Florence, Italy, 3Henry Ford, Detroit, MI, 4U Wisconsin, Madison, WI, 5Loma Linda, Loma Linda, CA, 6Washington U, Saint Louis, MO, 7UCSF, SF, CA, 8Methodist, Houston, TX, 9Cleveland Clinic, Cleveland, OH, 10Mount Sinai, NY, NY, 11U Nebraska, Omaha, NE, 12Mayo, Jacksonville, FL, 13Cleveland Clinic, Weston, FL, 14Lahey, Burlington, MA, 15Indiana U, Indianapolis, IN, 16Vanderbilt, Nashville, TN, 17Ochsner, New Orleans, LA

    *Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
  • 2022 American Transplant Congress

    Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study

    N. Sulejmani1, D. Axelrod2, S. Dholakia1, S. Shah3

    1CareDx, South San Francisco, CA, 2University of Iowa, Iowa City, IA, 3University of Cincinnati, Cincinnati, OH

    *Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
  • 2022 American Transplant Congress

    A Novel Prospective Validation Trial Of Multiple Blood-based RNA Signature Assays Pre And Post Kidney Transplant To Predict Rejection

    L. Gallon1, P. O'Connell2, A. Chang3, M. Donovan4

    1Northwestern Univ, Chicago, IL, 2Westmead Inst, Sydney, Australia, 3Univ of Chicago, Chicago, IL, 4Verici Dx, Franklin, TN

    *Purpose: The accuracy and utility of clinically defined and analytically validated predictive biomarkers in kidney transplantation is limited. We leveraged prior feasibility blood-RNA studies to…
  • 2022 American Transplant Congress

    Outcomes of COVID-19 in Solid Organ Transplant Recipients in Canada 2020-2021: A Prospective, Multicenter Cohort Study

    V. G. Hall1, G. Alahmadi2, J. T. Solera2, T. Marinelli2, H. Cardinal3, G. Prasad4, S. A. De Serres5, D. Isaac6, R. Mainra7, C. Lamarche8, R. Sapir-Pichhadze9, S. Gilmour10, A. Humar2, D. Kumar2

    1University Health Network/Toronto General Hospital, Toronto, ON, Canada, 2UHN, Toronto, ON, Canada, 3UMontreal, Montreal, QC, Canada, 4StMH, Toronto, ON, Canada, 5Laval U, Quebec, QC, Canada, 6UCalgary, Calgary, AB, Canada, 7USaskatchewan, Saskatoon, SK, Canada, 8HMR, Montreal, QC, Canada, 9McGill U, Montreal, QC, Canada, 10SCH, Edmonton, AB, Canada

    *Purpose: To understand the outcomes and changes in disease severity of COVID-19 in Solid Organ Transplant (SOT) recipients over time in the context of therapeutic…
  • 2022 American Transplant Congress

    Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Practice Patterns, Report from the Paramour “Pediatric Renal AMR Outcomes” Study

    N. Hayde1, K. Twombley2, I. Ashoor3, R. Engen4, L. Harshman5, R. Zahr6, C. Peterson7, S. McEwen8, A. Jain9, R. Garro10, M. Kallash11, A. Mansuri12, D. Puliyanda13

    1Montefiore Medical Center, Bronx, NY, 2Medical University of South Carolina, Charleston, SC, 3LCMCHealth, New Orleans, LA, 4Pediatrics, University of Wisconsin Madison, Madison, WI, 5University of Iowa Children's Hospital, Iowa City, IA, 6Le Bonheur Children's Hospital, Nashville, TN, 7University of Utah, Salt Lake City, UT, 8University of Minnesota, Minneapolis, MN, 9Wayne State, Troy, MI, 10Emory Universtiy, Atlanta, GA, 11The Ohio State, Columbus, OH, 12Augusta University Medical Center, Augusta, GA, 13Cedars-Sinai Med Ctr, West Hollywood, CA

    *Purpose: There is insufficient data on children with AMR in the literature, and the optimal therapy for AMR is not well defined. We aim to…
  • 2021 American Transplant Congress

    Early Detection of SARS-CoV-2 and Other Infections in Solid Organ Transplant Recipients and Household Members Using Wearable Devices

    E. H. Li1, E. Mukhtar1, E. D. Elftmann1, F. R. Eweje1, H. Gao1, L. I. Ibrahim1, R. G. Kathawate1, A. C. Lee1, K. A. Moore1, N. Nair1, S. Amaral2, M. Snyder3, B. J. Keating1

    1Department of Surgery, Penn Transplant Institute, Division of Transplantation, Philadelphia, PA, 2Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, 3Department of Genetics, Stanford University, Palo Alto, CA

    *Purpose: Wearable devices that measure physiological parameters have shown utility for detecting infections such as influenza and recently COVID-19 up to 10 days before clinical…
  • 2021 American Transplant Congress

    Outcomes of Downstaging Hepatocellular Carcinoma (HCC) to within Milan Criteria Before Liver Transplantation (LT): A Multicenter Analysis of the “All-comers” Protocol

    B. Natarajan1, P. Tabrizian2, M. Hoteit3, C. Frenette4, T. Ghaziani5, R. Dhanasekaran5, N. Parikh6, J. Guy7, A. Shui1, S. Florman2, F. Yao1, N. Mehta1

    1UCSF, SF, CA, 2Mt Sinai, NY, NY, 3U Penn, Philadelphia, PA, 4Scripps, La Jolla, CA, 5Stanford, Palo Alto, CA, 6U Michigan, Ann Arbor, MI, 7CPMC, SF, CA

    *Purpose: Patients with HCC meeting UNOS-downstaging (DS) criteria (1 lesion 5.1-8 cm, 2-3 lesions at least one 3.1-5 cm and total tumor diameter (TTD) ≤8…
  • 2021 American Transplant Congress

    Trends in Mortality Among Solid Organ Transplant Recipients Hospitalized for Covid-19 During the Course of the Pandemic

    M. R. Heldman, O. S. Kates, R. M. Rakita, E. D. Lease, C. E. Fisher, A. P. Limaye

    University of Washington, Seattle, WA

    *Purpose: Actual and comorbidity-adjusted mortality in hospitalized patients with COVID-19 has declined in the general population during the course of the pandemic. Whether a similar…
  • 2021 American Transplant Congress

    Gain of Function Mutations in Latent Membrane Protein 1 of Epstein Barr Virus are Associated with Increased Risk of Post-Transplant Lymphoproliferative Disorder

    O. M. Martinez1, S. M. Krams1, M. Robien2, M. Lapasaran1, M. Arvedson1, K. Weinberg1, S. Boyd1, B. Armstrong3, C. Twist4, D. Gratzinger1, B. Tan1, A. Trickey1, M. Sever3, M. Brown2, D. Bernstein1, C. O. Esquivel1

    1Stanford University Sch of Med, Stanford, CA, 2NIAID, Rockville, MD, 3Rho, Durham, NC, 4Roswell Park, Buffalo, NY

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. Clinical Trials of Organ Transplantation in Children (CTOTC)-06 is a prospective…
  • 2021 American Transplant Congress

    Kidney Transplantation Alone in Patients with Compensated Cirrhosis: A Multicenter Study

    A. Kassem1, S. Asrani1, S. W. Biggins2, Y. Darwish1, M. Nadim3, B. Fischbach1, T. Fong3

    1Baylor University Medical Center at Dallas, Dallas, TX, 2University of Washington, Seattle, WA, 3USC - Keck, Los Angeles, CA

    *Purpose: Patients undergoing kidney transplant (KTA) often have risk factors for liver disease including viral hepatitis and non-alcoholic fatty liver disease (NAFLD). Recent European Association…
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