Articles tagged "Multicenter studies"

2022 American Transplant Congress
Quality of Life of Brazilian Kidney Transplant Patients: A Sub-Project of ADHERE Brazil Multicenter Study
A. R. Almeida¹, F. R. Grincenkov², F. A. Colugnati¹, J. O. Medina³, S. De Geest⁴, H. Sanders-Pinheiro¹, S. ADHERE BRAZIL¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Psychology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ³Nephrology, Hospital do Rim. Federal University of São Paulo, São Paulo, Brazil, ⁴Department of Public Health, Institute of Nursing Science, Basel, Switzerland
*Purpose: While the quality of life (QoL) is known to improve after kidney transplant (KT), epidemiologic data are limited in Brazil. We aimed to describe…
2022 American Transplant Congress
Prediction Model of Post-Donation Renal Function Using Dynamic Kidney CT Volumetry in Living Donor
S. Lim¹, J. Kwon², Y. Ko¹, H. Kwon¹, J. Jung¹, H. Kwon¹, Y. Kim¹, J. Park², K. Lee², S. Shin¹
¹Asan Medical Center, Seoul, Songpa, Korea, Republic of, ²Samsung Medical Center, Seoul, Gangnam, Korea, Republic of
*Purpose: The risk of renal failure after live kidney donation can be predicted based on various clinical information. We tried introduce a model to predict…
2022 American Transplant Congress
Delta Changes in Donor-Derived Cell-Free DNA (dd-cfDNA) Complement the Donor Fraction in Kidney Transplant Surveillance
A. Wiseman¹, M. Jagadeesan², G. Gupta³, V. Rao⁴, M. Narayanan⁵, N. Agrawal⁶, G. Shekhtman⁶, Y. Fu⁶, K. Pinney⁶, S. Anand⁷
¹Centura Health, Denver, CO, ²George Washington University, Washington, DC, ³Virginia Commonwealth University, Richmond, VA, ⁴Medical University of South Carolina, Charleston, SC, ⁵Baylor Scott and White, Austin, TX, ⁶CareDx, Brisbane, CA, ⁷Intermountain Healthcare, Murray, UT
*Purpose: Delta changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the…
2022 American Transplant Congress
Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients
A. Al Jurdi¹, R. B. Gassen¹, T. Borges¹, I. T. Lape¹, L. Morena¹, O. Efe¹, Z. Solhjou², R. El Fekih², C. Kotton¹, J. Azzi², L. Riella¹
¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA
*Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
2022 American Transplant Congress
Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)
D. J. Reich¹, A. Schlegel², M. Rizzari³, D. Foley⁴, M. DeVera⁵, W. Chapman⁶, G. Roll⁷, A. Saharia⁸, C. Quintini⁹, S. Florman¹⁰, S. Merani¹¹, S. Mao¹², A. Pinna¹³, M. Akoad¹⁴, C. Kubal¹⁵, S. Alexopoulos¹⁶, H. Bohorquez¹⁷
¹Drexel University, Philadelphia, PA, ²Careggi U, Florence, Italy, ³Henry Ford, Detroit, MI, ⁴U Wisconsin, Madison, WI, ⁵Loma Linda, Loma Linda, CA, ⁶Washington U, Saint Louis, MO, ⁷UCSF, SF, CA, ⁸Methodist, Houston, TX, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Mount Sinai, NY, NY, ¹¹U Nebraska, Omaha, NE, ¹²Mayo, Jacksonville, FL, ¹³Cleveland Clinic, Weston, FL, ¹⁴Lahey, Burlington, MA, ¹⁵Indiana U, Indianapolis, IN, ¹⁶Vanderbilt, Nashville, TN, ¹⁷Ochsner, New Orleans, LA
*Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
2021 American Transplant Congress
Early Detection of SARS-CoV-2 and Other Infections in Solid Organ Transplant Recipients and Household Members Using Wearable Devices
E. H. Li¹, E. Mukhtar¹, E. D. Elftmann¹, F. R. Eweje¹, H. Gao¹, L. I. Ibrahim¹, R. G. Kathawate¹, A. C. Lee¹, K. A. Moore¹, N. Nair¹, S. Amaral², M. Snyder³, B. J. Keating¹
¹Department of Surgery, Penn Transplant Institute, Division of Transplantation, Philadelphia, PA, ²Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Genetics, Stanford University, Palo Alto, CA
*Purpose: Wearable devices that measure physiological parameters have shown utility for detecting infections such as influenza and recently COVID-19 up to 10 days before clinical…
2021 American Transplant Congress
Outcomes of Downstaging Hepatocellular Carcinoma (HCC) to within Milan Criteria Before Liver Transplantation (LT): A Multicenter Analysis of the “All-comers” Protocol
B. Natarajan¹, P. Tabrizian², M. Hoteit³, C. Frenette⁴, T. Ghaziani⁵, R. Dhanasekaran⁵, N. Parikh⁶, J. Guy⁷, A. Shui¹, S. Florman², F. Yao¹, N. Mehta¹
¹UCSF, SF, CA, ²Mt Sinai, NY, NY, ³U Penn, Philadelphia, PA, ⁴Scripps, La Jolla, CA, ⁵Stanford, Palo Alto, CA, ⁶U Michigan, Ann Arbor, MI, ⁷CPMC, SF, CA
*Purpose: Patients with HCC meeting UNOS-downstaging (DS) criteria (1 lesion 5.1-8 cm, 2-3 lesions at least one 3.1-5 cm and total tumor diameter (TTD) ≤8…
2021 American Transplant Congress
Trends in Mortality Among Solid Organ Transplant Recipients Hospitalized for Covid-19 During the Course of the Pandemic
M. R. Heldman, O. S. Kates, R. M. Rakita, E. D. Lease, C. E. Fisher, A. P. Limaye
University of Washington, Seattle, WA
*Purpose: Actual and comorbidity-adjusted mortality in hospitalized patients with COVID-19 has declined in the general population during the course of the pandemic. Whether a similar…
2021 American Transplant Congress
Gain of Function Mutations in Latent Membrane Protein 1 of Epstein Barr Virus are Associated with Increased Risk of Post-Transplant Lymphoproliferative Disorder
O. M. Martinez¹, S. M. Krams¹, M. Robien², M. Lapasaran¹, M. Arvedson¹, K. Weinberg¹, S. Boyd¹, B. Armstrong³, C. Twist⁴, D. Gratzinger¹, B. Tan¹, A. Trickey¹, M. Sever³, M. Brown², D. Bernstein¹, C. O. Esquivel¹
¹Stanford University Sch of Med, Stanford, CA, ²NIAID, Rockville, MD, ³Rho, Durham, NC, ⁴Roswell Park, Buffalo, NY
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. Clinical Trials of Organ Transplantation in Children (CTOTC)-06 is a prospective…
2021 American Transplant Congress
Kidney Transplantation Alone in Patients with Compensated Cirrhosis: A Multicenter Study
A. Kassem¹, S. Asrani¹, S. W. Biggins², Y. Darwish¹, M. Nadim³, B. Fischbach¹, T. Fong³
¹Baylor University Medical Center at Dallas, Dallas, TX, ²University of Washington, Seattle, WA, ³USC - Keck, Los Angeles, CA
*Purpose: Patients undergoing kidney transplant (KTA) often have risk factors for liver disease including viral hepatitis and non-alcoholic fatty liver disease (NAFLD). Recent European Association…