2017 American Transplant Congress
Tissue Transcriptional Profile of Portal Inflammation with Interface Activity in Pediatric Liver Transplant (LT) Recipients with Normal Liver Tests Closely Resembles T Cell Mediated Rejection (TCMR).
Background: Significant inflammation±fibrosis is frequently seen in biopsies (bxs) of pediatric LT recipients with normal liver tests assessed for immunosuppression withdrawal. The pathogenesis of these…2017 American Transplant Congress
Donor-Derived Cell-Free DNA Is a Dynamic Biomarker of Active Rejection in Kidney Allografts.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) has shown promise as a biomarker in identification of allograft rejection. Here we report on the changes in dd-cfDNA prior…2017 American Transplant Congress
Donor-Derived Cell-Free DNA Normal Range and Biological Variation Defined in a Reference Population.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) in the circulating blood of transplant recipients has shown promise as a non-invasive biomarker of acute rejection. This analysis was…2017 American Transplant Congress
Variability in Tacrolimus Concentrations Across Pediatric Solid Organ Transplants.
PURPOSE: We characterized the evolution of out-of-range tacrolimus (TAC) concentrations and associated factors during 1 year following a pediatric solid organ transplant (SOT).METHODS: Heart, kidney…2017 American Transplant Congress
Perceived Patient Barriers for Kidney Transplant Evalution Among Transplant Center Staff.
Background: The Southeastern United States has the lowest rates of kidney transplant in the nation. Disparities in transplant access among end stage renal disease (ESRD)…2017 American Transplant Congress
Hispanic Paradox in Patients with Liver Cirrhosis.
Northwestern University Transplant Research Collaborative, Chicago
IntroductionA paradoxical survival advantage for Hispanics compared to non-Hispanic whites (NHW) has been well described for many clinical conditions e.g diabetes however, with respect to…2017 American Transplant Congress
Racial Differences in Liver Cirrhosis-Related Mortality Among Patients with Model for End-Stage Liver Disease Sodium Score (MELDNa) ≤ 15.
Introduction:Subpopulations of patients with liver cirrhosis exist for whom the Model for End-Stage Liver Disease Sodium Score (MELDNa) is suboptimal for mortality prediction and who…2017 American Transplant Congress
Clinical Significance of Alloantibodies in Hand Transplantation: Impact on Rejection and Functional Outcome.
Purpose: Although alloantibodies, and donor-specific antibodies (DSA) in particular, are well-known to negatively impact graft survival in human solid organ transplantation, little is known about…2017 American Transplant Congress
Extraction Time During Liver Retrieval Impairs Survival After Transplantation.
During donor hepatectomy, despite topic cooling to 10-20[deg]C, the liver still sustains warm ischemia that might be harmful.We investigated the relationship between extraction time (ET)…2017 American Transplant Congress
Desensitization versus Deceased Donor Kidney Transplantation: What to Choose When Both Become Available?
1UCSF, San Francisco; 2Johns Hopkins, Baltimore; 3NYU, New York
Kidney allocation system changes have improved deceased donor kidney transplant (DDKT) access for highly sensitized patients. For patients with a willing live donor but requiring…
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