ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Mononuclear leukocytes"

  • 2015 American Transplant Congress

    Mononuclear Cell Infiltrates Characterization in Scar Tissue from a Bilateral Forearm Transplant Patient: Findings to Think

    J. Furuzawa-Carballeda,1 M. Iglesias,2 J. Alberu,3 A. Gamboa,4 P. Butrón,2 M. Morán-Romero,2 Y. Esquivel.1

    1Immunology, INCMNSZ, Mexico City, Mexico; 2Plastic Surgery, INCMNSZ, Mexico, Mexico; 3Transplants, INCMNSZ, Mexico, Mexico; 4Pathology, INCMNSZ, Mexico City, Mexico.

    Herein we report the cell infiltrating pattern in scar tissue resected at the junction of the VCA and the tissue corresponding to the recipient arm,…
  • 2015 American Transplant Congress

    Innate Immune Memory to Allogeneic Non-Self

    H. Dai, A. Williams, M. Oberbarnscheidt, F. Lakkis.

    Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    A hallmark of adaptive immunity is the generation of long-lived, antigen-specific memory T, B, and NK lymphocytes that mount strong anamnestic (recall) responses to previously…
  • 2015 American Transplant Congress

    A Specific Inhibitor of C1s, TNT003, Prevents Complement-Mediated Enhancement of Monocyte Adhesion to Endothelium in Response to HLA Antibodies

    N. Valenzuela,1 K. Thomas,1 A. Mulder,2 G. Parry,3 S. Parker,3 E. Reed.1

    1Immunogenetics Center, UCLA, Los Angeles, CA; 2Leiden University, Leiden, Netherlands; 3True North Therapeutics, San Francisco, CA.

    HLA antibody (Ab) mediated complement activation on endothelial cells (EC) is likely a critical driver of antibody-mediated inflammation. Production of complement anaphylatoxins by HLA antibodies…
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