ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Mononuclear leukocytes"

  • 2015 American Transplant Congress

    Mononuclear Cell Infiltrates Characterization in Scar Tissue from a Bilateral Forearm Transplant Patient: Findings to Think

    J. Furuzawa-Carballeda,1 M. Iglesias,2 J. Alberu,3 A. Gamboa,4 P. Butrón,2 M. Morán-Romero,2 Y. Esquivel.1

    1Immunology, INCMNSZ, Mexico City, Mexico; 2Plastic Surgery, INCMNSZ, Mexico, Mexico; 3Transplants, INCMNSZ, Mexico, Mexico; 4Pathology, INCMNSZ, Mexico City, Mexico.

    Herein we report the cell infiltrating pattern in scar tissue resected at the junction of the VCA and the tissue corresponding to the recipient arm,…
  • 2015 American Transplant Congress

    Single Cell Phospho-Protein Analysis Demonstrates That Immunosuppressive Drugs Inhibit MAPK and mTOR Signaling Molecules in Primary Monocytes After Transplantation

    N. Kannegieter, D. Hesselink, R. Kraaijeveld, G. de Graav, M. Betjes, W. Weimar, C. Baan.

    Nephrology and Transplantation, Dept. of Internal Medicine, Erasmus MC, Rotterdam, Netherlands.

    Monocytes have been identified as key players driving rejection processes. It is therefore surprising that there are almost no data available about the impact of…
  • 2015 American Transplant Congress

    A Specific Inhibitor of C1s, TNT003, Prevents Complement-Mediated Enhancement of Monocyte Adhesion to Endothelium in Response to HLA Antibodies

    N. Valenzuela,1 K. Thomas,1 A. Mulder,2 G. Parry,3 S. Parker,3 E. Reed.1

    1Immunogenetics Center, UCLA, Los Angeles, CA; 2Leiden University, Leiden, Netherlands; 3True North Therapeutics, San Francisco, CA.

    HLA antibody (Ab) mediated complement activation on endothelial cells (EC) is likely a critical driver of antibody-mediated inflammation. Production of complement anaphylatoxins by HLA antibodies…
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