Articles tagged "Metabolic complications"

2022 American Transplant Congress
Associations of Immunosuppression Regimen with Fracture Risk After Kidney Transplant in High-Risk Populations: Identifying Targets for Risk-Reduction
K. Lentine¹, S. Kupacchi², W. Cheungpasitporn³, R. Li⁴, Y. Caliskan⁴, M. Schnitzler⁴, M. McAdams-DeMarco⁵, J. Ahn⁵, S. Bae⁶, G. Hess⁷, D. Segev⁵, D. Axelrod²
¹Saint Louis University Center for Abdominal Transplantation, St. Louis, MO, ²U Iowa, Iowa City, IA, ³Mayo Clinic, Rochester, MN, ⁴Saint Louis University, Saint Louis, MO, ⁵Johns Hopkins, Baltimore, MD, ⁶Johns Hopkins, Baltimore, MO, ⁷Drexel, Philadelphia, MO
*Purpose: Disorders of bone and mineral metabolism frequently develop with advanced kidney disease, may be exacerbated by immunosuppression (ISx) after kidney transplant (KTx), and may…
2022 American Transplant Congress
Sodium-Glucose Cotransporter 2 Inhibitors to Treat Diabetes Mellitus After Kidney Transplant
H. M. Brokmeier¹, S. B. Leung¹, A. Kukla², K. C. Mara³, P. Shah⁴, Y. Kudva⁴, G. K. Mour⁵, H. M. Wadei⁶, J. M. Hill⁷, M. D. Stegall⁸, A. Lemke¹
¹Pharmacy, Mayo Clinic, Rochester, MN, ²Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN, ⁵Nephrology Transplant, Mayo Clinic, Phoenix, AZ, ⁶Nephrology, Mayo Clinic, Jacksonville, FL, ⁷Transplant, Mayo Clinic, Rochester, MN, ⁸Division of Transplant Surgery, Mayo Clinic, Rochester, MN
*Purpose: This study describes experience prescribing sodium-glucose cotransport 2 inhibitors (SGLT2i) after kidney transplant to evaluate safety and effectiveness.*Methods: This is a retrospective, institutional review…
2022 American Transplant Congress
Recipient TIM4+ Macrophage is a Central Hub for Metabolic Homeostasis in Liver Transplantation: From Mouse-to-Human
H. Hirao, K. Kadono, H. Kojima, K. J. Dery, D. G. Farmer, F. M. Kaldas, J. Kupiec-Weglinski
UCLA, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major risk factor for early graft dysfunction and predisposes to rejection in orthotopic liver transplantation (OLT). Previous studies…
2022 American Transplant Congress
Pegloticase for Uncontrolled Gout in Kidney Transplant Recipients: Provisional Data Report of a Multicenter, Open-Label, Efficacy and Safety Study
A. Abdellatif¹, L. Zhao², K. Cherny², B. Marder², J. D. Scandling³, K. Saag⁴
¹Division of Nephrology, Baylor College of Medicine, Houston, TX, ²Horizon Therapeutics PLC, Deerfield, IL, ³Division of Nephrology, Stanford School of Medicine, Stanford, CA, ⁴Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Gout in kidney transplant (KT) recipients can be severe and particularly challenging to manage. Pegloticase co-therapy with immunomodulators improved urate lowering therapy (ULT) response…
2022 American Transplant Congress
Living Related Liver Transplantation for Children with Metabolic Diseases- The Earlier the Better
M. Schulze, A. Aldana, M. Shagrani, D. D. Broering
Organ Transplant Centre of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: Metabolic defects in children are rare throughout the world, however if diagnosed too late they can cause severe neurological irreversible deterioration, eventually being fatal.…
2022 American Transplant Congress
Bisphosphonates for Fracture Prevention in Kidney Transplant Recipients
J. Kahwaji¹, S. Yang², J. Sim³
¹Nephrology/Transplant, Kaiser Los Angeles Medical Center, Los Angeles, CA, ²Research and Evaluation, Kaiser-Permanente, Pasadena, CA, ³Nephrology, Kaiser Los Angeles Medical Center, Los Angeles, CA
*Purpose: Kidney transplant recipients are at increased risk of fracture, however bisphosphonate use has not be shown to lower fracture risk in this population. We…
2022 American Transplant Congress
The Impact of New-Onset Diabetes After Transplantation on Survival and Major Cardiovascular Events in Korean Kidney Transplantation Recipients
E. Kang¹, J. Lee², D. Kang³, Y. Jang⁴, S. Park⁵, Y. Kim⁴, D. Kim⁴, K. Joo⁴, Y. Kim⁴, M. Park⁶, Y. Lim⁷, H. Lee⁴
¹Ewha Womans University Seoul Hospital, Seoul, Korea, Republic of, ²Dongguk University Ilsan Hospital, Goyang, Korea, Republic of, ³Chung-Ang University, Seoul, Korea, Republic of, ⁴Seoul National University Hospital, Seoul, Korea, Republic of, ⁵Seoul National University College of Medicine, Seoul, Korea, Republic of, ⁶Informations and Statistics, Chungnam National University, Daejeon, Korea, Republic of, ⁷Applied Statistics, Chung-Ang University, Seoul, Korea, Republic of
*Purpose: New-onset diabetes after transplantation (NODAT) is a frequent complication in kidney transplant (KT) recipients with unfavorable outcomes, although a nationwide study on epidemiology and…
2022 American Transplant Congress
Single Center Retrospective Study Examining the Safety of the New Potassium- Binders for Post-Operative Hyperkalemia in Kidney Transplant Recipients
S. Kapoor¹, A. Campbell², Y. Azzi¹, L. E. Liriano-Ward³, T. Shertel⁴, W. Xiao⁵, D. U. Nnani⁶, S. Farghaly¹, S. Yun⁷, E. Akalin¹, M. Ajaimy¹
¹Einstein-Montefiore Transplant Center, Bronx, NY, ²Montefiore Medical Center, Bronx, NY, ³Transplant, Montefiore Medical Center, Bronx, NY, ⁴-, -, AL, ⁵Albert Einstein College of Medicine, Folsom, CA, ⁶Pharmacy, Montefiore Medical Center, Bronx, NY, ⁷Montefiore Medical Center, New York, NY
*Purpose: We aimed to evaluate the safety and efficacy of two potassium-binders (Patiromer and Sodium Zirconium Cyclosilicate (SZC) in early post-transplant hyperkalemia treatment of kidney…
2022 American Transplant Congress
The Impact of Donor’s Metabolic Syndrome Factor on Living Kidney Transplantation
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: Because donors for kidney transplantation are also aging in Japan, it is not uncommon that donors have metabolic syndrome (Met-S). It is necessary to…
2021 American Transplant Congress
Insulin Secretion and Insulin Resistance Trajectories Over 1 Year After Kidney Transplantation: A Multicenter Prospective Cohort Study
B. Jun Bae, C. Oh
Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of
*Purpose: We investigated the changing patterns of insulin secretion and resistance and risk factors contributing to the development of post-transplant diabetes mellitus (PTDM) in kidney…