Articles tagged "Meta-analysis"

2018 American Transplant Congress
The Treatment of Antibody-Mediated Rejection in Kidney Transplantation: An Updated Systematic Review and Meta-Analysis
S. Wan,^1,2 T. Ying,^1,2 K. Wyburn,^1,2 D. Roberts,^3,4 M. Wyld,^1,2 S. Chadban.^1,2
¹Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; ²Sydney Medical School, University of Sydney, Sydney, Australia; ³Department of Renal Medicine, Canberra Hospital and Health Services, Canberra, Australia; ⁴Medical School, Australian National University, Canberra, Australia.
Introduction: Current treatment strategies for antibody-mediated rejection (AMR) in kidney transplantation are based on low quality data from a small number of controlled trials. Novel…
2018 American Transplant Congress
Evaluation the Outcomes of Liver Transplant Recipients Underwent Splenectomy: A Meta-Analysis
M. Chen, X. Lin, B. Huang, X. He.
Organ Transplant Center, Sun yat-sen University, Guangzhou, China.
Background. Splenectomy is performed as strategy of modulating the portal vein pressure in most of portal hypertension patients with liver cirrhosis. In liver transplantation, researchers…
2018 American Transplant Congress
A Meta-Analysis for Induction Therapy of Kidney Transplantation: Comparison of Antithymocyte Globulin and Interleukin 2 Receptor Antagonist
G. Chen, Z. Wu, C. Wang, X. Liu, C. Wang, L. Chen.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Objectives To compare the efficacy and safety of antithymocyte globulin (ATG) and interleukin 2 receptor antagonist (IL2Ra) in induction therapy of kidney transplantation.Method A literature…
2018 American Transplant Congress
The Efficacy and Safety of Rituximab as Induction Therapy in Kidney Transplantation: A Meta-Analysis of Randomized Controlled Trials
X. Wang,¹ J. Chen,² X. Tu,² Y. Qiu,¹ T. Song,¹ T. Lin.¹
¹Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; ²West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan Province, China.
Objectives. This meta-analysis was undertaken to assess the efficacy and safety of rituximab as induction therapy in kidney transplantation.Methods. OVID, Embase, SCI, PubMed and EBSCO…
2018 American Transplant Congress
The Association between Transplant Glomerulopathy and Graft Outcomes among Patients Undergoing Kidney Transplantation: Results of a Meta-Analysis
G. Kovács,¹ G. Devercelli,² Z. Vokó,^1,3 T. Zelei,¹ I. Hirji,² P. Keown.^4,5
¹Syreon Research Institute, Budapest, Hungary; ²Shire, Lexington, MA; ³Health Policy & Health Economics, Eötvös Loránd University, Budapest, Hungary; ⁴Syreon Corporation, Vancouver, BC, Canada; ⁵University of British Columbia, Vancouver, BC, Canada.
Transplant glomerulopathy (TG) can lead to irreversible kidney damage. TG is recognized as a surrogate marker for poor outcomes, including graft failure and loss among…
2018 American Transplant Congress
Precision (re)Phenotyping of Histologically Stable Kidney Transplants
D. Rychkov,¹ T. Sigdel,² M. Sirota,¹ M. Sarwal.²
¹Institute for Computational Health Sciences, UCSF, San Francisco, CA; ²Department of Surgery, UCSF, San Francisco, CA.
Background: Acute Rejection (AR) is the main cause of the renal failure within one year after transplantation (tx). Its earlier diagnosis is crucial for a…
2017 American Transplant Congress
CMV and BK Virus Infections in Kidney Transplant Recipients Receiving an mTORi-Based Regimen versus a CNI-Based Regimen: A Systematic Review and Meta-Analysis.
B. Tanios,¹ S. Mallat,¹ H. Itani,¹ T. Lotfi,¹ S. Gabardi,² E. Akl,¹ J. Azzi.²
¹Division of Nephrology, American University of Beirut Medical Center, Beirut, Lebanon; ²Renal Division, Harvard Medical School, Boston
The objective of this systematic review is to compare the incidence of CMV and BK virus infections in kidney transplant recipients receiving an mTORi-based as…
2016 American Transplant Congress
Therapeutically Equivalent Results to Caucasians in Black Kidney Transplant Recipients Using ASTAGRAF XL^® Despite a Higher Degree of HLA Mismatch : A Post-Hoc Analysis of Phase III Data from Over 2000 Patients.
J. Schwartz, S. Wilson, F. Shi, N. Undre, M. Kumar.
Astelleas Pharma Global Develepment, Northbrook, IL.
INTRO: When contemplating the use of a new immunosuppressant agent in kidney transplantation, measuring outcomes in potentially vulnerable populations is of paramount concern. As such,…
2016 American Transplant Congress
Systematic Review and Meta-Analysis of the Impact of Computed Tomography Assessed Skeletal Muscle Mass on Outcome in Patients Awaiting or Undergoing Liver Transplantation.
J. van Vugt,¹ S. Levolger,¹ R. de Bruin,¹ J. van Rosmalen,² H. Metselaar,³ J. IJzermans.¹
¹Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; ²Biostatistics, Erasmus University Medical Center, Rotterdam, Netherlands; ³Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.
BackgroundAlthough liver transplant outcome has improved significantly, the shortage of human organs remains prevalent. Therefore, strict patient selection is of paramount importance. Recently, low CT-assessed…
2016 American Transplant Congress
Pediatric Patients Benifit from Steroids Free Regimen After Kidney Transplantation: A Meta-Analysis.
R. Deng, H. Zhang, Y. Zheng, L. Liu, C. Wang.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Objective: To evaluate the effect of steroids avoidance or withdrawal (SAW) protocol on pediatric recipients by performing a meta-analysis of randomized controlled trials (RCTs).Method: A…