Session Time: 3:15pm-4:00pm
Presentation Time: 3:30pm-4:00pm
*Purpose: Cannabis is the most commonly used recreational drug in the United States and transplant acceptability for cannabis using candidates varies among transplant centers. In addition, prevalence and impact of cannabis use on outcomes of kidney transplant (KTx) recipients remain unclear. The aims of this study were to summarize 1) the prevalence and 2) impact of cannabis use on outcomes after KTx.
*Methods: A literature search was performed using Ovid MEDLINE, EMBASE, and Cochrane Databases from inception until September 2019 to identify studies assessing prevalence of cannabis use among Ktx recipients and reported adverse outcomes after Ktx. Effect estimates from the individual studies were obtained and combined utilizing random-effects, generic inverse variance method of DerSimonian-Laird.
*Results: 4 cohort studies with a total of 55,897 Ktx recipients were enrolled. Overall, the pooled estimated prevalence of cannabis use was 3.2% (95%CI: 0.4%-20.5%). While the use of cannabis was not significantly associated with all-cause allograft failure [OR: 1.31 (95% CI, 0.70-2.46)] or mortality [OR: 1.52 (95% CI, 0.59-3.92], the use of cannabis among KTx recipients was significantly associated with increased death-censored graft failure with pooled OR of 1.72 (95% CI, 1.13-2.60).
*Conclusions: The overall estimated prevalence of cannabis use among KTx recipients is 3.2%. The use of cannabis is associated with increased death-censored graft failure, but not mortality after KTx.
To cite this abstract in AMA style:Vaitla P, Thongprayoon C, Rivera FCabeza, Koller F, Matemavi P, Kanduri S, Marathi R, Cheungpasitporn W. Epidemiology of Cannabis Use and Associated Outcomes among Kidney Transplant Recipients a Meta Analysis [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/epidemiology-of-cannabis-use-and-associated-outcomes-among-kidney-transplant-recipients-a-meta-analysis/. Accessed October 24, 2020.
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