Articles tagged "marginal"

2020 American Transplant Congress
Artificial Intelligence May Detect Donor Liver Steatosis and Predict Early Post-Transplantation Graft Failure
R. R. Narayan, L. Yang, N. Abadilla, S. B. Chen, J. P. Higgins, M. L. Melcher
Stanford University, Stanford, CA
*Purpose: To compare the accuracy of donor liver biopsy slides scored by manual histopathologic review versus a computer vision artificial intelligence (CVAI) platform to predict…
2018 American Transplant Congress
Pharmacological Defatting of Steatotic Human Livers Using a Novel Perfusion Solution during Normothermic Machine Perfusion
Y. Boteon,^1,2 J. Attard,^1,2 R. Laing,^1,2 A. Boteon,¹ R. Bhogal,¹ G. Reynold,² D. Neil,¹ H. Mergental,¹ D. Mirza,¹ S. Afford.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Introduction: Steatosis is the leading reason for donor livers discarding and contributes significantly to the worsening shortage of organs for transplantation. Steatotic livers commonly fail…
2018 American Transplant Congress
Predictors of Graft Survival amongst Recipients of Liver Allografts with Prolonged Cold Ischemic Time (CIT)
J. Steggerda,¹ K. Kim,¹ D. Malinoski,² M. Bloom.¹
¹Surgery, Cedars-Sinai Medical Center, Los Angeles, CA; ²Surgery, Oregon Health Science University, Portland, OR.
Background: CIT is an independent risk factor for worse outcomes in liver transplantation (LT). Factors contributing to improved graft survival in organs with CIT ≥12…
2018 American Transplant Congress
Effect of Kidney Allocation System on a Solitary, Isolated, Rural Transplant Program
K. Brown,² S. Hill,² L. Lipscomb,² A. Jones,² J. Africa.¹
¹Glickman Institute, Cleveland Clinic, Cleveland, OH; ²Urology and Renal Transplant, Charleston Area Medical Center, Charleston, WV.
The new kidney allocation system (KAS) was expected to create an impact on smaller, rural and geographically isolated centers.Methods. We examined the changes by the…
2018 American Transplant Congress
Long-Term Outcomes of Primary Kidney Transplant from Expanded Criteria Maastricht Category 3 DCD Donors: A Single-Centre Observational Study
E. Favi,¹ C. Puliatti,² S. Iesari,³ M. Ferraresso,¹ R. Cacciola.²
¹Kidney Transplantation, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; ²Kidney Transplantation, The Royal London Hospital, London, United Kingdom; ³Kidney Transplantation, University of L'Aquila, L'Aquila, Italy.
Background. Kidney transplants (KTx) from standard (STD) DCD donors have higher rates of primary non function (PNF) and delayed graft function (DGF) than DBD but…
2018 American Transplant Congress
Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?
D. Kollmann,¹ S. Neong,¹ R. Rosales,¹ G. Sapisochin,¹ M. Bhat,¹ M. Cattral,¹ P. Greig,¹ L. Lilly,¹ D. McGilvray,¹ A. Ghanekar,¹ D. Grant,¹ M. Selzner,¹ F. Wong,² N. Selzner.¹
¹Multi Organ Transplant, Toronto General Hospital, Toronto, Canada; ²Division of Gastroenterology, Toronto General Hospital, Toronto, Canada.
Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…
2018 American Transplant Congress
Extracellular Microvesicles from Liver Perfusate: microRNAs, Cellular Cross-Talk, and Early-Post Liver Transplant Outcomes
A. Fernandez,¹ O. Ingram,¹ S. Bontha,¹ U. Erdbruegger,² L. Musante,² V. Mas,¹ D. Maluf.¹
¹Surgery, UVA, Charlottesville; ²Nephrology Division, UVA, Charlottesville.
Background: Ischemia reperfusion injury (IRI) is a multifactorial process that impact liver graft function. Donor quality plays a critical role during IRI and early graft…
2018 American Transplant Congress
Diffuse Optical Non-Invasive Organ Risk (DONOR) Indexing Using Diffuse Reflectance Spectroscopy for Pre-Transplant Evaluation
H. Borron,¹ D. Piao,² A. Hawxby,³ H. Wright,³ E. Rubin.⁴
¹College of Medicine, University of Oklahoma, Oklahoma City, OK; ²School of Electrical and Computer Engineering, Oklahoma State University, Stillwater, OK; ³Oklahoma Transplant Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK; ⁴Pathology, University of Oklahoma, Oklahoma City, OK.
Purpose: Due to large transplant waitlists, a rapid, non-invasive method to evaluate organ quality for transplantation is needed. Diffuse optical spectroscopy (DOSi) is an optical…
2018 American Transplant Congress
The Impact of Marginal Factors on Postoperative Kidney Function of Complex Living Donors for Kidney Transplantation
T. Hiramitsu, K. Futamura, M. Okada, M. Tsujita, T. Ichimori, N. Goto, S. Narumi, Y. Watarai.
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan.
BackgroundRecently, complex living donors with marginal factors including hypertension, dyslipidemia, glucose intolerance, and obesity are increasing. Postoperative kidney function of living donors for kidney transplantation…
2018 American Transplant Congress
Predicting Early and Late eGFR Variability in Kidney Transplant Recipients
K. Soliman, D. Taber, S. Zemin, V. Rao.
Department of Medicine and Department of Surgery, MUSC, Charleston, SC.
Introduction: eGFR variability is a known risk factor for graft loss. It is unclear what modifiable factors are significantly associated with this variability and if…

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