Articles tagged "Malignancy"

2018 American Transplant Congress
TP53 Mutations Lead to Increased Transcription of Circular RNAs in Exosomes Enhancing Tumor Invasiveness in Hepatocellular Carcinoma Bases on Bioinformatics Analysis
Z. Yu, Y. Hou, R. Wang, X. Huang.
The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Objective Increasing evidence suggests that cicular RNAs play an important role in tumor. A recent study found the enrichment of cicular RNAs in HCC derived…
2018 American Transplant Congress
Impact of Elevated PSA, and Prostate Cancer in ESRD on Time to Transplant, and Survival
N. Sarabu,¹ N. Schiltz,² D. Hricik.¹
¹University Hospitals of Cleveland, Cleveland, OH; ²Case Western Reserve University, Cleveland, OH.
Introduction: Despite concerns for over-diagnosis and over-treatment from prostate cancer screeening, transplant centers perform it. We studied effect of Elevated PSA, and Prostate cancer on…
2018 American Transplant Congress
Prediction of Hepatocellular Carcinoma Recurrence Following Liver Transplantation Using Combined Differential Gene Expression, Copy Number Variation and Somatic Mutation Analysis
A. Humar,¹ P. Liu,² J. Luo,³ M. Nalesnik,³ A. Singhi,³ G. Tseng,² G. Michalopoulos.³
¹Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; ²Biostatistics, University of Pittsburgh, Pittsburgh, PA; ³Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.
Liver allocation for transplant candidates with hepatocellular carcinoma is limited by OPTN policy to patients whose tumors remain within size limits defined by Milan criteria.…
2018 American Transplant Congress
Long-Term Follow-Up of Patients with Primary Sclerosing Cholangitis Undergoing Liver Transplantation with Duct-to-Duct Biliary Reconstruction
L. Coromina Hernandez, B. Eghtesad, T. Diago, K. Hashimoto, M. Fujiki, C. Quintini, F. Aucejo, G. Iuppa, A. Hassan, N. Menon, C. Miller.
Transplant Surgery, Cleveland Clinic, Cleveland, OH.
Background:Reconstruction of biliary drainage after liver transplantation (LTx) in patients with primary sclerosing cholangitis (PSC) has been a matter of controversy. Over the recent years,…
2018 American Transplant Congress
Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma Treated with Neoadjuvant Therapy: A Pilot Cohort Study
K. Lunsford,¹ M. Javle,² K. Heyne,¹ R. Shroff,² R. Hassan Ali,² C. Mobley,¹ D. Victor,¹ A. Kaseb,² T. Aloia,² C. Conrad,² X. Li,¹ H. Monsour,¹ A. Gaber,¹ J-.N. Vauthey,² R. Ghobrial.¹
¹Houston Methodist Hospital, Houston, TX; ²MD Anderson Cancer Center, Houston, TX.
INTRODUCTIONIntrahepatic cholangiocarcinoma (iCCA) is a well-recognized contraindication for liver transplantation (LT). Recent reports indicate favorable LT outcomes for early iCCA (<2cm), but, poor survival persists…
2018 American Transplant Congress
Impact of Antecedent Malignancy on Kidney Transplant Outcomes: Patient, Graft, and Cancer-Free Survival
O. Serrano,¹ S. Mongin,² D. Berglund,¹ D. Vock,³ S. Chinnakotla,¹ T. Dunn,¹ E. Finger,¹ R. Kandaswamy,¹ T. Pruett,¹ A. Matas.¹
¹Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, Minneapolis, MN; ³Biostatistics, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Non-skin pretransplant malignancy (NSPTM) has historically been considered a relative contraindication to kidney transplantation (KT). In addition to the conventional risk factors for cancer,…
2018 American Transplant Congress
Risk Factors of De Novo Malignancies after Liver Transplantation
M. Altieri,¹ O. Seree,² J. Dumortier,³ GREF2 Groupe de Recherche Français en Greffe de Foie.
¹Service d'HepatoGastroenterologie, Nutrition et Oncologie Digestive, CHU de Caen, Caen, France; ²Réseau Régional de Cancérologie Onco-Basse-Normandie, Herouville Saint-Clair, France; ³Service d'HepatoGastroenterologie, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Lyon, France.
De novo malignancies after liver transplantation (LT) are one of the leading causes of late mortality, with a reported risk of malignancies twice as high…
2018 American Transplant Congress
A Population Based Study of Incidence of Post Kidney Transplant Malignancies
D. Sexton,¹ J. O'Neill,² P. O'Kelly,¹ S. Murray,¹ S. Deady,³ E. O'Leary,³ P. Morris,⁴ P. Conlon.¹
¹Department of Nephrology & Transplantation, Beaumont Hospital Dublin, Royal College of Surgeons Ireland, Dublin, Ireland; ²Department of Otolaryngology, Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland; ³National Cancer Registry Ireland, Cork, Ireland; ⁴Department of Oncology, Beaumont Hospital, Dublin, Ireland.
IntroductionWe aimed to report national standardised incidence for malignancy post transplant compared to the general population stratified by solid organ categories. In this study we…
2018 American Transplant Congress
Tumor Recurrence in Kidney Transplant Recipients with a History of Pretransplant Malignancy
F. Becker,¹ K. Schütte Nütgen,² S. Reuter,² L. Kebschull,¹ T. Vowinkel,¹ N. Senninger,¹ D. Palmes,¹ T. Vogel,¹ R. Bahde.¹
¹Department for General and Visceral Surgery, University Hospital Münster, Münster, Germany; ²Department of Internal Medicine D, University Hospital Münster, Münster, Germany.
Introduction: A growing body of evidence indicates that kidney transplant recipients (KTR) with a history of pre-transplant malignancy (PTM)have a higher incidence of post-transplant de-novo…
2018 American Transplant Congress
Pre-Existing Renal Cell Carcinomas in Patients with Polycystic Kidney Disease Undergoing Simultaneous Native Nephrectomy and Living Donor Kidney Transplantation
M. Aull,¹ J. Del Pizzo,² A. Watkins,¹ S. Kapur.¹
¹Surgery, Weill Cornell Medical College, New York, NY; ²Urology, Weill Cornell Medical College, New York, NY.
Due to the structural changes to the kidney that occur in polycystic kidney disease (PKD), imaging tests may not pick up pre-transplant renal cancers in…