2019 American Transplant Congress
Total Parenteral Nutrition in Ex Vivo Lung Perfusion: Addressing Metabolism Improves Both Inflammation and Overall Graft Performance
Department of Surgery, Division of Cardiac Surgery, University of Alberta, Edmonton, AB, Canada
*Purpose: Contemporary clinical ex vivo lung perfusion (EVLP) protocols generally limit metabolic supplementation to insulin and glucose. Furthermore, conventional perfusates are void of many ingredients…2019 American Transplant Congress
Pharmacological Enhancement of Bile Duct Preservation and Function during Ex-Situ Normothermic Machine Perfusion
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: Whilst ex-situ normothermic machine perfusion (NMP) of the liver limits the ischaemic injury to the organ, benefits for biliary complications post-transplantation are not yet…2018 American Transplant Congress
Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion
Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…2018 American Transplant Congress
Viability Outcomes for Donor Livers Discarded Due to Steatosis Following Extra-Corporeal Machine Perfusion of the Liver
Background: Steatosis is the main reason for discarding donor livers worldwide. Ex-vivo machine perfusion offers superior preservation for marginal organs and permits viability testing during…2018 American Transplant Congress
Molecular Injury and Repair Assessment in Ex Vivo Perfused Swine Heart Transplants
University of Alberta, Edmonton, Canada.
Background: Cardiac transplantation is a life-saving intervention for advanced heart failure but it is unfortunately limited by a critical shortage of suitable donor organs and…2018 American Transplant Congress
Use of Perfusion Machine after Long Cold Ischemia Time: 3 Years Results
The rate of delayed graft function (DGF) in Brazil is very high, reaching 80%. This is due to the long cold ischemia time (TIF) and…2018 American Transplant Congress
Normothermic Machine Perfusion (NMP) Preservation for Human Liver Transplantation in the Cleveland Clinic
Cleveland Clinic, Cleveland, OH.
NMP is a novel preservation method for liver grafts. We transplanted 15 human livers after NMP to test the safety and feasibility of NMP on…2018 American Transplant Congress
Variation in Hypothermic Machine Perfusion Utilization and Clinical Outcomes for Deceased-Donor Kidneys
Introduction:Hypothermic machine perfusion (HMP) has been shown to be an effective method for preserving kidney allografts from deceased donors (1), but data suggests that low-risk…2018 American Transplant Congress
Pharmacological Defatting of Steatotic Human Livers Using a Novel Perfusion Solution during Normothermic Machine Perfusion
Introduction: Steatosis is the leading reason for donor livers discarding and contributes significantly to the worsening shortage of organs for transplantation. Steatotic livers commonly fail…2018 American Transplant Congress
Hypothermic Machine Perfusion Protects DCD Liver Graft through Metabolism of Xenobiotics by Cytochrome P450 Pathway
Background: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
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