2022 American Transplant Congress
The SHELTER Trial of Transplanting Donor Hepatitis C Virus RNA+ Lungs Into Uninfected Recipients
1University of Pennsylvania, Philadelphia, PA, 2University of Miami, Miami, FL
*Purpose: The advent of direct acting antiviral therapy has motivated centers to transplant lungs from donors with hepatitis C virus infection (HCV-RNA+) into uninfected recipients.…2022 American Transplant Congress
Transbronchial Cryobiopsy vs Conventional Forceps Biopsy in Lung Transplant Recipients Multicenter Study
*Purpose: Transbronchial biopsy is considered the gold standard in the diagnosis of acute cellular rejection after lung transplantation. There still remains the discussion in conventional…2022 American Transplant Congress
Simultaneous Lung and Kidney Transplant in a Young Patient with COVID-19
*Purpose: Lung transplant is the last resort for COVID-19 refractory ARDS. Dual organ transplant is seen as a relative contraindication at many institutions. We describe…2022 American Transplant Congress
CD31+ Extracellular Vesicles in Ex Vivo Lung Perfusion Are Associated with Unsuitability for Transplant
*Purpose: Primary graft dysfunction (PGD) is an important cause of morbidity and mortality following lung transplantation and results in part from injuries sustained in the…2022 American Transplant Congress
Longitudinal Analysis of the Lung Microbiome and Immune Status in Lung Transplant Recipients
Shanghai Pulmonary Hospital, Shanghai, China
*Purpose: The dynamic remodeling of lung flora structure and the association between microbial community dynamics and immune status after lung transplantation (LTx) remain unclear.*Methods: Fourteen…2022 American Transplant Congress
Lung Transplantation Outcomes in Recipients Living with HIV in the United States
*Purpose: To compare outcomes of lung transplantation in HIV-positive and HIV-negative recipients in the United States.*Methods: A national transplant database (UNOS/SRTR) was queried for cases…2022 American Transplant Congress
Impact of Belatacept on Clinical Outcomes in Lung Transplant Patients with Antibody-Mediated Rejection
*Purpose: Antibody-mediated rejection (AMR) is cause of significant morbidity and mortality in lung transplant recipients (LTRs). An optimal therapeutic regimen is still lacking. Recent evidence…2022 American Transplant Congress
The Impact of Tacrolimus Trough Variability on Acute Rejection Following Lung Transplantation
*Purpose: This study aimed to evaluate the association of tacrolimus coefficient of variation (CV) with biopsy-proven acute cellular rejection in the first year following lung…2021 American Transplant Congress
Liver Kinase B1 Knockdown Induces Platelet-Derived Growth Factor Receptor B Expression in Human Airway Epithelial Cells: A Potential Mechanism for Development of Fibrosis Leading to Chronic Lung Allograft Dysfunction
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: The platelet-derived growth factor and its receptor (PDGFRb) signaling pathway can be activated by epithelial mesenchymal transition which facilitates fibrosis. It is not known…2021 American Transplant Congress
Evaluating Pneumocystis Jiroveci Pneumonia Prophylaxis in Lung Transplant Recipients
Michigan Medicine, Ann Arbor, MI
*Purpose: The incidence of Pneumocystis jiroveci pneumonia (PJP) in lung transplant recipients (LTRs) on PJP prophylaxis is not well documented yet reported as high as…
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