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American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2022 American Transplant Congress

    Prevalence and Characteristics of Covid-19-Associated Pulmonary Diagnoses in Lung Transplant Patients in the United States

    T. G. Mupfudze1, A. R. Wilk1, R. R. Goff1, M. Valapour2, J. Miller3, M. Budev2, E. D. Lease4

    1Research Department, United Network for Organ Sharing, Richmond, VA, 2Respiratory Institute, Cleveland Clinic, Cleveland, OH, 3Scientific Registry of Transplant Recipients, Minneapolis, MN, 4Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA

    *Purpose: Lung transplant may be a viable treatment option for select patients with non-recoverable COVID-19-associated acute respiratory distress syndrome (ARDS) and COVID-19-associated pulmonary fibrosis. This…
  • 2022 American Transplant Congress

    Top Molecules Associated with CLAD in Lung Transplants Are Shared Between Mucosal Biopsies, Transbronchial Biopsies, and Kidney Transplant Biopsies at Risk of Progression

    M. Mackova1, K. Halloran2, P. F. Halloran1, .. and the INTERLUNG Study Group3

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2University of Alberta, Edmonton, AB, Canada, 3., ., AB, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD) is a physiologic state with grave consequences for progression to failure but cannot be diagnosed by biopsy histology. We…
  • 2022 American Transplant Congress

    Outcomes in Lung Transplant Recipients Switched from Tacrolimus to Cyclosporine Due to Hyperammonemia Early Post-Transplantation

    S. Goyal, J. Lyons, P. Stracener, B. Bemiss

    Loyola University Medical Center, Chicago, IL

    *Purpose: Assess the impact of switching from tacrolimus to cyclosporine due to hyperammonemia on outcomes at 1-year post-lung transplant.*Methods: A retrospective review of lung transplant…
  • 2022 American Transplant Congress

    The Impact of Long-Term Exposure to Tacrolimus on Chronic Kidney Disease Following Lung Transplantation: A Retrospective Analysis from a Single Transplantation Center

    D. Xiong, J. Zhang, J. Chen

    Lung Transplantation Center, Department of Thoracic Surgery, Wuxi People’s Hospital Affiliated to Nanjing Medical Univer, Wuxi, China

    *Purpose: Chronic kidney disease (CKD) is a progressive and irreversible complication in lung transplant patients who have received long-term treatment with tacrolimus. This study aimed…
  • 2022 American Transplant Congress

    Safety and Efficacy of Peri-Vaccination Antimetabolite Hold to Augment Third SARS-CoV-2 Vaccine Dose Response in Lung Transplant Recipients

    S. Frey, J. Ruck, J. Alejo, L. Barker, W. Werbel, R. Avery, D. Segev, P. Shah

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Lung transplant recipients (LTRs) are less likely than other solid organ transplant recipients (SOTRs) to develop an antibody response to SARS-CoV-2 vaccination. Mycophenolate has…
  • 2022 American Transplant Congress

    Angiotensin II-Regulated Proteins Production by Pulmonary Macrophages in Chronic Lung Allograft Dysfunction

    S. Farkona1, A. Duong2, G. Berra2, S. Moshkelgosha2, S. Clotet-Freixas1, S. Juvet2, T. Martinu2, A. Konvalinka1

    1Toronto General Hospital Research Institute and Multi-Organ Transplant, University Health Network, Toronto, ON, Canada, 2Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD), characterized by fibrosis, is the most important cause of mortality after lung transplantation. CLAD mechanisms remain poorly understood and…
  • 2022 American Transplant Congress

    Clinical Impact of a Modified Lung Allocation Score That Mitigates Selection Bias

    E. M. Schnellinger1, E. Cantu2, D. E. Schaubel1, S. E. Kimmel3, A. J. Stephens-Shields1

    1University of Pennsylvania, Philadelphia, PA, 2Hospital of the University of Pennsylvania, Philadelphia, PA, 3University of Florida, Gainesville, FL

    *Purpose: The U.S. lung allocation system uses the Lung Allocation Score (LAS) to prioritize lung transplant candidates. Selection bias, induced by dependent censoring of waitlisted…
  • 2022 American Transplant Congress

    Direct Central Ambulatory Venoarterial Extracorporeal Membrane Oxygenation and Double Lung Transplantation without Graft Reduction with Extreme Mediastinal Shift

    A. Gorton1, S. Keshavamurthy2

    1Cardiothoracic Surgery, University of Kentucky, Lexington, KY, 2University of Kentucky, Lexington, KY

    *Purpose: Double Lung transplantation in the presence of extreme mediastinal shift can be technically challenging due to donor sizing and recipient factors.*Methods: We present the…
  • 2021 American Transplant Congress

    20 Year Survival Following Lung Transplantation

    R. M. Reul, Jr1, S. Barrett1, A. Alnajar2, J. Dunson1, P. S. Garcha3, G. Loor4, J. A. Goss4, A. A. Rana4

    1Office of Student Affairs, Baylor College of Medicine, Houston, TX, 2Department of Surgery, University of Miami Health System, Miami, FL, 3Department of Medicine, Baylor College of Medicine, Houston, TX, 4Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: Outcomes following lung transplantation (LTx) have been poor compared to those of heart, liver, and kidney transplants, with 5-year survival rates around 50%. To…
  • 2021 American Transplant Congress

    Endothelial Glycocalyx Shedding is Associated with Graft Quality During Ex Vivo Lung Perfusion

    K. Noda, B. J. Philips, T. Harano, J. D. Luketich, P. G. Sanchez

    Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Endothelial glycocalyx is the surface protective layer of the endothelial cells and its damage is known to be strongly associated with organ dysfunction. However,…
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