2022 American Transplant Congress
Impact of Belatacept on Clinical Outcomes in Lung Transplant Patients with Antibody-Mediated Rejection
*Purpose: Antibody-mediated rejection (AMR) is cause of significant morbidity and mortality in lung transplant recipients (LTRs). An optimal therapeutic regimen is still lacking. Recent evidence…2022 American Transplant Congress
The Impact of Tacrolimus Trough Variability on Acute Rejection Following Lung Transplantation
*Purpose: This study aimed to evaluate the association of tacrolimus coefficient of variation (CV) with biopsy-proven acute cellular rejection in the first year following lung…2022 American Transplant Congress
More Than Just Drain Pipes, Pulmonary Lymphatics Play a Pivotal Role in the Development of Bronchiolitis Obliterans Syndrome
*Purpose: Chronic allograft dysfunction (CLAD) remains a major determinant of the generally poor long-term outcome of lung transplantation compared to that of other solid organ…2022 American Transplant Congress
Risk Factors for Extubation Failure Post- Lung Transplantation
*Purpose: Extubation delays following lung transplantation can result in delirium, deconditioning, infections, and increased hospital length of stay. Risk stratifying patients for extubation failure may…2022 American Transplant Congress
Incidence and Laterality of Pulmonary Emboli in Single Lung Transplant Recipients
*Purpose: Lung transplantation surgery increases the risk of pulmonary embolism (PE), with an incidence described between 6% to 27%, based on data from 15 years…2022 American Transplant Congress
Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients
*Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…2022 American Transplant Congress
Poor Tolerability of CFTR Modulator Therapy in Lung Transplant Recipients
*Purpose: Elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) is a highly effective therapy for cystic fibrosis (CF) with potential benefits in lung transplant recipients (LTRs) for extrapulmonary CF manifestations, however…2022 American Transplant Congress
Missed Opportunities in Lung Transplant
The Cleveland Clinic, Cleveland, OH
*Purpose: Recent changes in lung allocation policy seek to improve geographic disparities in access. This study aims to understand geographic variation in donor availability and…2022 American Transplant Congress
dd-cfDNA Varies Among Diagnostics Groups of Pulmonary AMR
*Purpose: Antibody mediated rejection (AMR) in lung transplant remains complex, with differential diagnosis often overlapping with other causes of lung dysfunction. Diagnostic certainty declines to…2022 American Transplant Congress
Strada Deficiency Results in Inhibition of Tumor Suppressor Gene Liver Kinase B1 Resulting in Epithelial Mesenchymal Transition Leading to Chronic Murine Lung Allograft Rejection
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Recently we demonstrated that tumor suppressor gene Liver Kinase B1 (LKB1) is down regulated in lung biopsies and in the circulating exosomes of lung…
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