2015 American Transplant Congress
Epidemiology and Outcomes of Non Tuberculous Mycobacterial (NTM) Infections in Solid Organ Transplant (SOT) Recipients
Infectious Diseases, Washington University School of Medicine, St. Louis, MO.
Background: NTM are uncommon causes of infection in SOT recipients but may cause significant morbidity and mortality.Methods: A retrospective cohort of all patients who underwent…2015 American Transplant Congress
The Preservation Technique Modulates the Immunological Milieu in Lung Transplantation and Affects the Pro-/ Anti-Inflammatory Balance
Little is known regarding the influence of different preservation techniques (i.e. cold static storage with Perfadex® or Celsior® solution) on the immunological milieu, especially lung-resident…2015 American Transplant Congress
MicroRNA (miR) 144 Dysregulates TGFβ Signaling Cascade and Contributes to Development of BOS Following Human Lung Transplantation
1Surgery, Washington Univ Sch Med, St. Louis, MO; 2Medicine, Washington Univ Sch Med, St. Louis, MO.
Background: Bronchiolitis Obliterans Syndrome (BOS) is characterized by a fibroproliferative cascade that is not amenable to current treatment regimens and remains the major impediment for…2015 American Transplant Congress
Extracorporeal Life Support: A Rescue Therapy in a Lung Transplantation Program
Purpose: Extracorporeal Life Support (ECLS) is increasingly used as a bridge to lung transplantation (LTx) as well as in the management of severe primary graft…2015 American Transplant Congress
Marrow Mesenchymal Stem Cells Attenuate Immune Rejection in Murine Lung Allograft
Objectives:The inherent immunosuppressive properties and low immunogenicity of mesenchymal stems cells (MSCs) suggested their therapeutic potential in transplantation. In this study we investigated if systematic…2015 American Transplant Congress
Bortezomib-Based Multi-Modality Protocol for Donor-Specific Antibody Treatment in Lung Transplant Recipients
Duke University Hospital, Durham, NC.
Background Donor specific antibodies (DSAs) after lung transplant have been implicated in the development of chronic lung allograft dysfunction and mortality. The ideal treatment strategy…2015 American Transplant Congress
Lifor Organ Preservation Solution Protects Pulmonary Microvasculature in a Rat Model of Ex Vivo Lung Perfusion and Transplantation
A. Ex Vivo Lung Perfusion (EVLP) has emerged as an innovative method for lung preservation. Microvascular dysfunction and breakdown of endothelial barrier during EVLP are…2015 American Transplant Congress
Operating Room Extubation After Bilateral Lung Transplantation in Cystic Fibrosis Patients: A Single Center Experience
Short-acting anesthetic drugs, thoracic epidural analgesia and a strict ventilation weaning protocol could permit extubation in the operating room (OR) (1). Aims of this study…2015 American Transplant Congress
C1q Reactivity and IgG Subtypes After HLA Antibody Removal Therapy With Carfilzomib in Thoracic Transplant Recipients
Univ of Pittsburgh, Pittsburgh.
Conventional therapies for antibody removal consisting of plasma exchange with IVIG and Rituximab are partially effective in desensitization protocols and for treatment of antibody mediated…2015 American Transplant Congress
Does Pulmonary Rehabilitation Impact Frailty?
Purpose: Frailty is an emerging risk factor for morbidity and mortality in advanced lung disease and lung transplantation. Interventions to reduce frailty in this population…
American Transplant Congress abstracts