2015 American Transplant Congress
A New Diagnostic Tool for Antibody Mediated Rejection in Heart and Lung Transplantation: Intragraft Donor Specific Anti-HLA Antibodies Detection
INTRODUCTION: Antibody mediated rejection (AMR) is one of the causes of dysfunction and graft loss. The limited histological features, with a weak sensibility of c4d,…2015 American Transplant Congress
Lung Biopsy Findings in Pediatric Lung Transplant Patients With Restrictive Physiology
Background: Long-term survival in pediatric lung transplantation is limited by bronchiolitis obliterans (BO), but varieties of chronic lung allograft dysfunction (CLAD) are poorly understood. Restrictive…2015 American Transplant Congress
Post Transplant De Novo Donor Specific Antibodies Correlate With the Development of Bronchiolitis Obliterans Syndrome Following Pediatric Lung Transplantation
Texas Children's Hospital, Houston, TX; Baylor College of Medicine, Houston, TX.
HLA donor specific antibodies (DSA) have been associated with poor allograft survival following adult solid organ transplantation (Tx). However, there is little evidence implicating post-Tx…2015 American Transplant Congress
Epidemiologic Change in Pulmonary Hypertension Patients Referred for Lung Transplantation Post Lung Allocation Score Implementation
Introduction: The lung allocation score (LAS) was designed and implemented in May 2005 to account for various measures of a candidate's health in an attempt…2015 American Transplant Congress
Th17 Mediates Inflammatory Responses After Lung Transplantation
Background: Long-term outcomes after lung transplantation are markedly worse than for other organs. The mechanisms that determine lung transplant rejection are not clear. The role…2015 American Transplant Congress
Long Term Survival After Single Versus Double Lung Transplantation in Patients With Pulmonary Fibrosis in the Modern Era of the Lung Allocation Score
Surgery, Temple University Hospital, Philadelphia, PA.
Objectives: To examine long-term survival in patients with idiopathic pulmonary fibrosis (IPF) after the implementation of the lung allocation score (LAS) in single lung transplantation…2015 American Transplant Congress
Epidemiology and Outcomes of Non Tuberculous Mycobacterial (NTM) Infections in Solid Organ Transplant (SOT) Recipients
Infectious Diseases, Washington University School of Medicine, St. Louis, MO.
Background: NTM are uncommon causes of infection in SOT recipients but may cause significant morbidity and mortality.Methods: A retrospective cohort of all patients who underwent…2015 American Transplant Congress
The Preservation Technique Modulates the Immunological Milieu in Lung Transplantation and Affects the Pro-/ Anti-Inflammatory Balance
Little is known regarding the influence of different preservation techniques (i.e. cold static storage with Perfadex® or Celsior® solution) on the immunological milieu, especially lung-resident…2015 American Transplant Congress
MicroRNA (miR) 144 Dysregulates TGFβ Signaling Cascade and Contributes to Development of BOS Following Human Lung Transplantation
1Surgery, Washington Univ Sch Med, St. Louis, MO; 2Medicine, Washington Univ Sch Med, St. Louis, MO.
Background: Bronchiolitis Obliterans Syndrome (BOS) is characterized by a fibroproliferative cascade that is not amenable to current treatment regimens and remains the major impediment for…2015 American Transplant Congress
Extracorporeal Life Support: A Rescue Therapy in a Lung Transplantation Program
Purpose: Extracorporeal Life Support (ECLS) is increasingly used as a bridge to lung transplantation (LTx) as well as in the management of severe primary graft…