Articles tagged "Lung transplantation"

2018 American Transplant Congress
Time and Perfusate Dependent Molecular Response in Ex Vivo Lung Perfusion
P. Dromparis,¹ N. Aboelnazar,² S. Wagner,¹ S. Himmat,² C. White,² J. Luc,² D. Freed,² J. Nagendran,² M. Mengel,¹ B. Adam.¹
¹Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada; ²Department of Surgery (Cardiac), University of Alberta, Edmonton, Canada.
Lung transplantation has limited organ utilization and high rates of primary graft dysfunction, in part due to acute lung injury (ALI). Cold static preservation (CSP)…
2018 American Transplant Congress
The Aggressive Phenotype: Center-Level Characteristics in the Use of Suboptimal Lungs
M. Kosztowski, E. Bush, X. Luo, A. Thomas, M. Bowring, D. Segev, J. Garonzik Wang.
Johns Hopkins, Baltimore, MD.
The disparity between organ supply and demand has led some centers to expand their criteria for donor selection. We explored utilization of suboptimal lungs to…
2018 American Transplant Congress
Risk Factors for Postoperative Bleeding after Lung Transplantation
D. Adelmann,^1,2 S. Koch,¹ J. Menger,¹ P. Jaksch,³ M. Kurz,¹ M. Mouhieddine,¹ W. Klepetko,³ B. Steinlechner.¹
¹Department of Anesthesia, General Intensive Care and Pain Control, Medical University of Vienna, Vienna, Austria; ²Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA; ³Medical University of Vienna, Vienna, Austria.
Bleeding complications after lung transplantation (LuTX) are associated with increased morbidity. Risk factors for postoperative bleeding complications after LuTX have not yet been reported. In…
2017 American Transplant Congress
Antibody Mapping by Protein Microarray Revealed a Unique Repertoire in Lung Transplant Recipients That Developed Chronic Lung Allograft Dysfunction.
D. Nayak,¹ K. Garcia,² P. Pirrotte,² R. Hachem,³ R. Bremner,¹ M. Smith,¹ T. Mohanakumar.¹
¹Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ; ²Translational Genomics Research Institute, Phoenix, AZ; ³Washington University, St. Louis, MO
Background: Development of chronic lung allograft dysfunction (CLAD) limits long-term success from lung transplantation (LTx). Elicitation of de novo antibody (Ab) to mismatched donor HLA…
2017 American Transplant Congress
Propensity-Score Matched Comparison of Lung Transplant Recipients of Age <70 and ≥70 Years.
A. Kashem,¹ S. Keshavamurthy,¹ J. Gomez-Abraham,¹ T. Yoshizumi,¹ H. Zhao,² F. Cordova,³ G. Criner,³ Y. Toyoda.¹
¹Cardiovascular Surgery, Temple University, Philadelphia, PA; ²Clinical Sciences, Temple University, Philadelphia, PA; ³Thoracic and Pulmonary Medicine, Temple University, Philadelphia, PA
Purpose: To validate the utilization of lung transplantation (LTx) recently in older recipients, we compared the survival outcome of the LTx recipients of age <70…
2017 American Transplant Congress
Autotransplantation of the Left Lung for the Treatment of Recurrent Life Threatening Pulmonary Hemorrhage Related to Pulmonary Vascular Malformation: A Unique Chance to Study Ischemia/Reperfusion Injury.
C. Falk,¹ I. Tudorache,² C. Müller,³ W. Sommer,² K. Daemen,¹ J. Keil,¹ G. Hansen,³ A. Haverich,² G. Warnecke,² N. Schwerk.³
¹Institute of Transplant Immunology, IFB-Tx, MHH, Hannover, Germany; ²Department of Cardiothoracic Transplant and Vascular Surgery, MHH, Hannover, Germany; ³Department of Pediatric Pneumology, MHH, Hannover, Deutschland, Germany
Background: Ischemia reperfusion injury (IRI) remains a major clinical problem in lung transplantation. Here, we report the investigation of IRI in a 17-year-old patient who…
2017 American Transplant Congress
Addition of FEV1 Drop to LAS May Improve Access of CF Patients to Transplant: Analysis of the SRTR and US CF Foundation Patient Registries.
E. Dasenbrook,¹ M. Skeans,² A. Fink,³ B. Marshall,³ M. Valapour.^1,2
¹Cleveland Clinic, Cleveland; ²SRTR, Minneapolis; ³CF Foundation, Bethesda
Lung transplant is a widely accepted treatment for cystic fibrosis (CF) end-stage lung disease. The US lung allocation score (LAS) system prioritizes transplant candidates primarily…
2017 American Transplant Congress
Lung Transplant Recipient Travel Distance to Transplant Center Does Not Impact Survival.
W. Tsuang,¹ S. Lin,² J. Schold,² M. Valapour.¹
¹Respiratory Institute, Cleveland Clinic, Cleveland, OH; ²Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH
Purpose: We examined if the geographic distance recipients travel for lung transplant care impacts posttransplant survival at our center.Methods: Retrospective single center cohort study of…
2017 American Transplant Congress
Truth in Pathology: Autopsy Findings in Lungs Declined for Transplantation.
A. Friedman, J. Lewis, H. Irving, K. Delli Carpini.
LiveOnNY, New York, NY
Healthy lungs are scarce among available organ donors who are becoming progressively older and have increasing numbers of comorbidities. Selection criteria that include excellent oxygenation…
2017 American Transplant Congress
Long-Term Analysis of Combined Liver-Lung Transplant Outcomes at a Single-Center.
K. Freischlag,¹ B. Ezekian,² M. Mulvihill,² S. Knechtle.²
¹School of Medicine, Duke University, Durham, NC; ²Surgery, Duke University, Durham, NC
Purpose: Combined liver-lung transplantation (CLLT) is indicated in patients who would not be expected to survive transplantation of either organ alone. We present one of…