2018 American Transplant Congress
A Novel Preservation Solution for Lung That Improves Cell Viability and Tissue Architecture
1Tulane University, New Orleans; 2MUSC, Charleston.
Backgroud: Only 20% of donor lungs are used for transplant and 10 y survival of recipients is low. Many patients die within 30 d of…2018 American Transplant Congress
High Body Mass Index in Organ Donor is Significantly Correlated to Low PaO2/FiO2 Ratio in SRTR Database
Background:Atelectasis is a major cause of hypoxemia in organ donors. However, the risk factors of hypoxemia unknown. Our previous study suggested that donors with high…2018 American Transplant Congress
In Vitro Evaluation of Antibiotic Persistence in Pseudomonas aeruginosa and Staphylococcus aureus Isolates from Cystic Fibrosis Patients
UW Hospital & Clinics, Madison; UW School of Pharmacy, Madison.
Purpose: The mechanisms of antibiotic persistence in immunosuppressed populations are not fully understood. Patients with cystic fibrosis (CF), both the pre-transplant and post-transplant phase often…2017 American Transplant Congress
Risk Factors for Post-Transplant Lymphoproliferative Disorders in Epstein-Barr Virus Mismatch Lung Transplant Recipients.
Brigham and Women's Hospital, Boston
Background: Post-transplant lymphoproliferative disorders (PTLD) are associated with significant morbidity and morality. Lung transplant patients appear to have higher rates of PTLD than other solid…2017 American Transplant Congress
Outcomes of Combined Liver/Lung Transplantation for Cystic Fibrosis Using SRTR Analysis.
Cystic fibrosis is a genetic multi-system disease affecting approximately 1 in every 2500 newborns globally. Pulmonary transplantation is indicated in patients with severe bronchiectasis and…2017 American Transplant Congress
Successful Induction of Tolerance of Fully Allogeneic Lung Graft with Adenosine A2A Receptor (A2AR) Agonist in MHC-Defined CLAWN Miniature Swine.
Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan
Introduction: A2AR agonist is known to potently attenuate lung ischemia-reperfusion injury. However, the long-term effects of A2AR agonist on lung allograft survival remain unclear especially…2017 American Transplant Congress
C4d Immunohistochemistry in Lung Allograft Interstitial Capillaries Lacks Linear Correlation with Donor Specific Antibodies, yet It Is Still Diagnostically Relevant.
Antibody mediated rejection in lung allograft biopsies is not well defined from a morphologic or immunohistochemical aspect. Many centers routinely run immunohistochemistry for C4d as…2017 American Transplant Congress
Normothermic Donor Lung Preservation with Portable EVLP Significantly Reduces Ischemia/Reperfusion Injury in Lung Recipients by Promoting Cytokine Antagonists.
ObjectivesThe INSPIRE trial revealed significant reduction of PGD grade 3 using the Organ Care System (OCS) compared to the standard of care (SOC) for lung…2017 American Transplant Congress
HLA, ANA, and ANCA Negative Vasculitis in Lung Transplantation Due to Overexpression of α1 Collagen V.
The mechanism of fibrosing vasculopathy in lung allograft is poorly understood. A 58 year old man received a bilateral lung transplant for interstitial lung disease.…2017 American Transplant Congress
Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.
1University Health Network, Toronto, ON, Canada; 2Sinai Health System, Toronto, ON, Canada
IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…
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