ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2018 American Transplant Congress

    Respiratory Viral Infections Induces Exosomes and Antibodies to Lung Self-Antigens, Kα1Tubulin and Collagen V, Following Human Lung Transplantation

    M. Gunasekaran,1 S. Bansal,1 M. Sharma,1 R. Walia,1 R. Hachem,2 A. Limaye,3 R. Bremner,1 M. Smith,1 T. Mohanakumar.1

    1St. Joseph's Hosp & Med Ctr, Phoenix; 2Washington Univ Sch Med, St. Louis; 3Univ Washington, Seattle.

    Respiratory viral infection (RVI) following human lung transplantation (LTx) increases the risk for chronic rejection. We demonstrated that lung transplant recipients (LTxR) with acute and…
  • 2018 American Transplant Congress

    The Impact of ABO Blood Type and Geography on Access to Lung Transplant

    W. Tsuang, D. McMichael, X. Wang, M. Budev.

    Cleveland Clinic, Cleveland.

    Background: Rare blood types (B and AB) are increasingly a risk factor for lung transplant waitlist mortality when compared to common blood types (A and…
  • 2018 American Transplant Congress

    Evaluation of Survival and Maintenance Immunosuppression in Elderly Lung Transplant Recipients

    P. Nguyen,1 R. Girgis,1,2 E. Murphy,1,2 R. Hadley,1,2 M. Leacche,1,2 A. Kumar,1,2 G. Sathiyamoorthy,1,2 J. McDermott.1,2

    1Spectrum Health, Grand Rapids, MI; 2Michigan State University College of Human Medicine, Grand Rapids, MI.

    Background: Lung transplantation in the elderly is controversial given increased risks and the optimal immunosuppression regimen is not fully understood.Methods: A retrospective cohort study was…
  • 2017 American Transplant Congress

    Immune Monitoring-Guided Treatment of a Pediatric Patient with Sequential GvHD, Acute Rejection and CMV Infection Following Lung Transplantation.

    C. Falk,1 S. Nicolaus,2 M. Carsten,2 T. Igor,3 S. Wiebke,3 D. Kerstin,1 K. Jana,2 H. Gesine,2 H. Axel,3 W. Gregor.3

    1Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; 2Department of Pediatric Pulmology, Hannover Medical School, Hannover, Deutschland, Germany; 3Department of Cardiothoracic Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Deutschland, Germany

    Background: A 17 year old patient with cystic fibrosis (HLA-A11+, CMV-) underwent bilateral sequential lung transplantation (donor: HLA-A32+, CMV+). Immunosuppression (IS) consisted of Tacrolimus, MMF…
  • 2017 American Transplant Congress

    Impact of Caregiver on 30 Day Readmission After Lung Transplant.

    T. Coco, C. Keller, F. Alvarez, D. Erasmus, J. Mallea.

    Department of Transplantation, Mayo Clinic Florida, Jacksonville, FL

    The type of primary caregiver has been associated with long-term outcomes after lung transplantation. There is no data on the impact of caregiver associated with…
  • 2017 American Transplant Congress

    Outcomes After Lung Transplant: Being a Teenager Does Not Stop at Age 18.

    R. Baker,1 R. Rizwan,1 R. Bryant III,1 M. Schecter,2 C. Towe,2 J. Tweddell,1 F. Zafar,1 D. Morales.1

    1Cardiothoracic Surgery, Cincinnati Children's Hospital, Cincinnati, OH; 2Pulmonary Medicine, Cincinnati Children's Hospital, Cincinnati, OH

    Recipient age at lung transplantation impacts survival. Adolescent recipients grouped by legal age definition (12-18) have been shown across all types of solid organ transplantation…
  • 2017 American Transplant Congress

    Novel Biomarkers for Segregating Lung Transplant Rejection Phenotypes.

    J. Yang,1 B. Vanaudenaerde,2 T. Sigdel,1 J. Liberto,1 S. Verlden,2 M. Sarwal.1

    1Department of Surgery, University of California, San Francisco, San Francisco, CA; 2Department of Pneumology, University of Leuven, Leuven, Flemish Brabant, Belgium

    We sought to investigate biomarkers in BAL fluid and tissue for segregating BOS and RAS chronic rejection phenotypes in lung allografts. We had previously identified…
  • 2017 American Transplant Congress

    Characterization of a B Lymphocyte Signature Predictive of Chronic Lung Allograft Dysfunction.

    C. Brosseau,1,2 M. Durand,1,2 E. Durand,1,2 J. Loy,2 A. Foureau,2 P. Lacoste,2 P.-J. Royer,2 A. Magnan,2 S. Brouard.1

    1INSERM UMR1064, Centre de Recherche en Transplantation et, Nantes, France; 2INSERM UMR1087, Institut du Thorax, Nantes, France

    The occurrence of chronic lung allograft dysfunction (CLAD) is the main complication after lung transplantation (LT) and remains the most common cause of graft failure…
  • 2017 American Transplant Congress

    Preoperative Pulmonary Hypertension Is Not Associated with Adverse Outcomes After Lung Transplantation.

    S. Biswas Roy,1 M. Olson,2 D. Harned,1 P. Kang,3 R. Panchanathan,3 A. Hashimi,1 J. Huang,1 H. Abdelrazek,1 V. Patel,1 A. Omar,1 R. Bremner,1 M. Smith,1 R. Walia,1 A. Kalya.4

    1Norton Thoracic Institute, Phoenix; 2Grand Canyon University, Phoenix; 3University of Arizona, Phoenix; 4St. Joseph's Hospital and Medical Center, Phoenix

    Purpose: The effect of preoperative pulmonary hypertension (PH)[mdash]that is, mean pulmonary artery pressure (mPAP) of 25mmHg or higher[mdash]on lung transplantation (LTx) outcomes is debatable.Methods: We…
  • 2017 American Transplant Congress

    Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome Appearance After Lung Transplantation.

    R. Danger,1 P. Royer,2 D. Reboulleau,2 J. Loy,2 A. Tissot,2 P. Lacoste,2 A. Roux,3 M. Reynaud-Gaubert,4 R. Kessler,5 S. Mussot,6 C. Dromer,7 O. Brugière,8 J. Mornex,9 R. Guillemain,10 M. Dahan,11 C. Knoop,12 K. Botturi,2 C. Pison,13 L. Nicod,14 S. Brouard,1 A. Magnan,2 COLT and SysCLAD Consortia.

    1CRTI UMR1064, INSERM, Université de Nantes, ITUN, CHU Nantes, Nantes, France; 2UMR_S 1087 CNRS UMR_6291, Institut du Thorax, Université de Nantes, CHU de Nantes, Nantes, France; 3CHU de Marseille, Aix Marseille Université, Marseille, France; 4CHU de Strasbourg, Strasbourg, France; 5Service de Chirurgie Thoracique, Vasculaire et Transplantation Cardiopulmonaire, Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France; 6CHU de Bordeaux, Bordeaux, France; 7Service de Pneumologie et Transplantation Pulmonaire, Hôpital Bichat, Paris, France; 8Université de Lyon, INRA, UMR754, Lyon, Hospices Civils de Lyon, Lyon, France; 9Hôpital Européen George Pompidou, Paris, France; 10CHU de Toulouse, Toulouse, France; 11Hôpital Erasme, Bruxelles, Belgium; 12Clinique Universitaire Pneumologie, Pôle Thorax et Vaisseaux, CHU de Grenoble, Université de Grenoble, Inserm U1055, Grenoble, France; 13Service de Pneumologie, Centre de Transplantation, Lausanne, Switzerland

    Bronchiolitis obliterans syndrome (BOS) is the main manifestation of chronic lung allograft dysfunction responsible for the poor long-term outcome after lung transplantation. While physiopathological mechanisms…
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