2022 American Transplant Congress
Direct Central Ambulatory Venoarterial Extracorporeal Membrane Oxygenation and Double Lung Transplantation without Graft Reduction with Extreme Mediastinal Shift
*Purpose: Double Lung transplantation in the presence of extreme mediastinal shift can be technically challenging due to donor sizing and recipient factors.*Methods: We present the…2022 American Transplant Congress
Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients
*Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…2022 American Transplant Congress
Donor-Derived Cell-Free DNA Across the Spectrum of Solid Organ Transplantation
1Baylor Scott & White Health, Temple, TX, 2CareDx, Inc, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a robust and clinically useful analyte initially validated for kidney allograft surveillance. Emerging data support the utility of dd-cfDNA…2022 American Transplant Congress
Dynamic Changes and Roles of Specialized Pro-resolving Lipid Meditators in the Initiation and Resolution Process of Lung Ischemia-Reperfusion Injury in Rats
*Purpose: Lung ischemia-reperfusion injury (IRI) is one of the significant complications after lung transplantation, which is a form of acute lung injury by robust inflammation.…2022 American Transplant Congress
A Model of Idiopathic Pneumonia Syndrome in Rhesus Macaques
*Purpose: To create a model of idiopathic pneumonia syndrome (IPS), a deadly complication of hematopoietic stem cell transplantation (HSCT) in Rhesus macaques (RM).*Methods: RM were…2022 American Transplant Congress
Infection Impacts dd-cfDNA in Lung Transplant Recipients
*Purpose: Infection is the leading cause of death within 1 year post lung transplant. Graft injury secondary to infection is affected by both source and…2022 American Transplant Congress
Residential Mobility of Lung Recipients
*Purpose: The Final Rule from the U.S. Department of Health and Human Services mandates that patient geography should have a minimal role in organ transplant…2022 American Transplant Congress
Place Based Risk for Early Rejection in Lung Transplant
*Purpose: Within 5 years after lung transplant (LT), half of recipients have lost 20% or more of lung function. Despite a consistent link between social…2022 American Transplant Congress
OPTN Required SARS-CoV-2 Lower Respiratory Testing for Lung Donors: Early Impact on Patient Safety and Organ Utilization
*Purpose: The OPTN implemented emergency policy on 5/27/21 requiring lower respiratory testing (LRT) by nucleic acid test (NAT) for SARS-CoV-2 (COVID-19) for all potential deceased…2022 American Transplant Congress
Effect of Prophylactic Treatment of Osteoporosis on the Progression of Bone Mineral Density and Fractures in Lung Transplant Recipients – A Five-Year, Single-Center Experience
*Purpose: The incidence of osteoporotic fractures in lung transplant recipients (LTxR) is 35-50%. Due to this high incidence, we perform regular DEXA scans [pre-Tx, every…
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