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American Transplant Congress abstracts

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Articles tagged "Liver"

  • 2016 American Transplant Congress

    Racial Disparities in the Evaluation for Liver Transplantation.

    M. Jesse, E. Goldstein, N. Rebhan, C.-X. Ho, T. Macaulay, M. Bebanic, L. Shkokani, D. Moonka, M. Abouljoud, A. Yoshida.

    Transplant Institute, Henry Ford Health System, Detroit, MI.

    The majority of research on disparities in liver transplantation is on patients listed for transplant in the OPTN/UNOS database, not patients in the evaluation process…
  • 2016 American Transplant Congress

    Short-Term Starvation Attenuates Liver Ischemia Reperfusion Injury by SIRT1-Autophagy Signaling in Mice.

    J. Rao,1 H. Zhou,1 F. Zhang,1 X. Wang,1 Y. Zhai,2 L. Lu.1

    1Liver Transplantation Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, China; 2Dumont-UCLA Transplant Center, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles.

    Calorie restriction or starvation (fasting) has some beneficial effects on prolongation of life and increased resistance to stress. Calorie restriction has also been shown to…
  • 2016 American Transplant Congress

    Skipping Comparable Local Waitlist Candidates Under Share 35.

    E. Chow,1 A. Massie,1 X. Luo,1 C. Wickliffe,1 S. Gentry,2 A. Cameron,1 D. Segev.1

    1Surgery, Johns Hopkins University, Baltimore, MD; 2Mathematics, US Naval Academy, Annapolis, MD.

    Under Share-35, deceased donor (DD) livers are offered regionally to candidates with MELD≥35 before locally to lower MELD candidates. The characteristics and outcomes of local…
  • 2016 American Transplant Congress

    Psychiatric Characteristics of Acute Liver Failure Patients: Acetaminophen Overdose versus Other Etiologies.

    N. Rebhan, M. Bebanic, A. Yoshida, T. Macaulay, E. Goldstein, C.-X. Ho, A. Eshelman, M. Abouljoud, M. Jesse, M. Rizzari.

    Transplant Institute, Henry Ford Health System, Detroit.

    Scant research exists on the psychiatric history of patients with acute liver failure (ALF) presenting for liver transplantation. This study compared psychiatric profiles of patients…
  • 2016 American Transplant Congress

    A Pilot Study of Donor: A Smart Phone Application for Identifying Live Kidney and Liver Donors.

    K. Kumar,1 E. King,1 A. Muzaale,1 J. Konel,1 G. Segal,3 J. Arnold,3 K. Bramstedt,4 D. Segev,1,2 A. Cameron.1

    1Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; 2Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD; 3ORGANIZE, New York, NY; 4Bond University School of Medicine, Gold Coast, QLD, Australia.

    Background: With over 100,000 candidates waiting, rates of deceased donation stagnant, and only 17,000 Kidney and liver transplants a year, live donor transplantation may represent…
  • 2016 American Transplant Congress

    The Impact of Share 35 on Liver Allocation and Utilization: One DSA's Experience.

    J. Orlowski, C. Muse, J. Whaley, R. Squires.

    LifeShare of Oklahoma, Oklahoma City, OK.

    Background: In June 2013, U.S. liver allocation changed from a local-regional-national model to “Share 35”, broadening sharing to a regional level based upon recipient MELD…
  • 2015 American Transplant Congress

    Efficacy of Sofosbuvir Based Therapy for Recurrent Hepatitis C After Liver Transplantation

    A. Weick,1 K. George,1 S.-M. Jafri,2 D. Moonka.2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI; 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.

    Purpose: Evaluate outcomes of sofosbuvir-based hepatitis C therapy in liver transplant patients in a single center clinical setting, including interferon-free regimens.Methods: All patients with history…
  • 2015 American Transplant Congress

    Activation of FXR Protects Against Liver Ischemia and Reperfusion Injury (IRI) in Mice Via the PI 3-Kinase/Akt (PI3K/Akt) Pathway

    J. Zhang,1 X. Liu,2 D. Li,1 H. Dai,1 J. Zhang,1 T. Lu,1 Q. Xia.1

    1Liver Transplantation Center, Renji Hospital, Shanghai, China; 2Cardiovascular, Shanghai First People/s Hospital, Shanghai, China.

    Background: FXR is a ligand-dependent transcription factor belonging to the nuclear hormone receptor superfamily, which plays important roles in lipid metabolism, glucose homeostasis, inflammatory responses…
  • 2015 American Transplant Congress

    Neonatal Tolerance: Donor and Host Cells Fuse in Livers of Newborn Mice Injected With F1-Bone Marrow/Spleen Cells

    R. Bascom, K. Tao, S. Tollenaar, L. West.

    University of Alberta, Edmonton, Canada.

    Purpose: Multiple liver cell-types induce immunological tolerance. Indeed liver allografts are often spontaneously accepted in humans and mice. The role of host liver in the…
  • 2015 American Transplant Congress

    Macrophage Specific β-Catenin Controls ROCK/PTEN Function and Regulates Innate Immunity in Liver Inflammation

    S. Yue,1 X. Zhou,2 M. Zhou,1 Y. Zhai,1 R. Busuttil,1 Q. Ying,2 J. Kupiec-Weglinski,1 B. Ke.1

    1Dumont-UCLA Transplant Center, Dept. of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Dept. of Stem Cell Biology & Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

    Background: It has been shown that β-catenin is an important regulator of cell development, regeneration, and carcinogenesis. Our previous studies demonstrated the key role of…
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