2016 American Transplant Congress
Mesenchymal Stem Cells Reprogram Macrophage Polarization and Attenuate Liver Ischemia and Reperfusion Injury by Regulating Notch/Cox2/PGE2 Signaling Pathway.
Background and aims: Mesenchymal stem cells (MSCs) have been shown an immune modulatory properties and tissue repairing capability under inflammatory conditions. However, it is unknown…2016 American Transplant Congress
The Medication Level Variability Index (MLVI), a Behavioral Biomarker, Predicts Late Allograft Rejection in Pediatric Liver Transplant Recipients – A Prospective Multisite Study.
Objective: The MALT [Medication Adherence in children who had a Liver Transplant (LT), NCT-01154075, R01DK080740 (NIDDK)] multisite study prospectively evaluated a biomarker for erratic medication…2016 American Transplant Congress
Barriers to the Wider Utilization of Living Donor Liver Transplantation (LDLT).
Purpose: LDLT reduces waitlist mortality, improves access to transplantation and has post-transplant outcomes that are equivalent to or better than deceased donor transplant. Despite these…2016 American Transplant Congress
Anti-Inflammatory Effects of AAV-Mediated TIMP-1 Gene Transfer in Hepatic Ischemia-Reperfusion Injury.
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase1 (TIMP-1) is the…2016 American Transplant Congress
Utility of a Routine Bench Cholangiogram for Deceased Split Liver Procedure.
Background: Biliary complications can result in a significant morbidity for split liver graft recipients. The segmental biliary anatomy, particularly the left biliary system is poorly…2016 American Transplant Congress
Racial Disparities in Cognitive and Social Requirements Prior to Listing for Liver Transplant.
Transplant Institute, Henry Ford Health System, Detroit, MI.
Guidelines for liver transplant candidates outline increased engagement of social supports in the context of patient cognitive impairments. However, there is little direction when limitations…2016 American Transplant Congress
Activating Transcription Factor 5 (ATF5) Regulates Liver Ischemia/Reperfusion Injury.
Activating transcription factor 5 (ATF5), a member of the ATF/cAMP response element-binding proteins, is extremely highly expressed in the liver, the significance of which is…2016 American Transplant Congress
Impact of Proximity MELD/PELD Points on Liver Redistricting Scenarios.
Background: To address geographic disparity in liver allocation, a new organ distribution system consisting of 4 or 8 districts has been proposed (Gentry, Am J…2016 American Transplant Congress
Racial Disparities in the Evaluation for Liver Transplantation.
Transplant Institute, Henry Ford Health System, Detroit, MI.
The majority of research on disparities in liver transplantation is on patients listed for transplant in the OPTN/UNOS database, not patients in the evaluation process…2016 American Transplant Congress
Short-Term Starvation Attenuates Liver Ischemia Reperfusion Injury by SIRT1-Autophagy Signaling in Mice.
Calorie restriction or starvation (fasting) has some beneficial effects on prolongation of life and increased resistance to stress. Calorie restriction has also been shown to…
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