ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver"

  • 2018 American Transplant Congress

    Poverty, End Stage Liver Disease, and Transplantation in Georgia

    R. Lynch,1 K. Ross,1 J. Magliocca,1 D. Goldberg,2 R. Patzer.1

    1Surgery, Emory University, Atlanta, GA; 2Medicine, University of Pennsylvania, Philadelphia, GA.

    Background: Though discussions of equity in liver transplantation remain focused primarily on relative availability of allografts as a measure of access, differences in disease burden…
  • 2018 American Transplant Congress

    Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver Resident Macrophage M2 Polarization via C/EBP-Homologous Protein-Mediated Endoplasmic Reticulum Stress

    Z. Rao, J. Sun, X. Pan, Z. Chen, H. Sun, P. Zhang, M. Gao, Z. Ding, C. Liu.

    Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

    Background:Aggravated liver ischemia and reperfusion (IR) injury has been observed in hyperglycemic hosts, but its underlying mechanism remains undefined. The aim of the study was…
  • 2018 American Transplant Congress

    Cumulative United States Experience in Domino Liver Transplants

    K. Barrera, S. Sharma, A. Gruessner, R. Gruessner.

    Surgery, State University of New York, Downstate, Brooklyn, CA.

    Background/Purpose: The ongoing shortage of livers in the setting of growing waiting lists remains a challenge in transplantation. First introduced in 1995, sequential or domino…
  • 2018 American Transplant Congress

    Liver Transplantation as a Life Saving Procedure after Post Resection Liver Failure and Iatrogenic Liver Injuries

    T. Thorsen,1 J. Solheim,1 R. Horneland,1 P-.D. Line,1 K. Labori,2 E. Aandahl.1

    1Section for Transplant Surgery, Oslo University Hospital, Oslo, Norway; 2Section for Hepatobiliary Surgery, Oslo University Hospital, Oslo, Norway.

    Introduction: Iatrogenic injuries to vital structures of the liver and liver failure post liver resection are both associated with high mortality. Selected patients that were…
  • 2017 American Transplant Congress

    Evaluation of the Enhanced Recovery After Surgery Protocol in Living Liver Donors.

    A. Khalil, S. Ganesh, C. Hughes, A. Tevar, J. Hatche, S. Esper, A. Humar.

    Abdominal Transplant, UPMC, Pittsburgh, PA; Department of Surgery, Ain Shams University, Cairo, Egypt

    Background: Enhanced recovery after surgery protocol has proven its efficacy in many surgery fields in controlling pain and promoting early recovery . The implication of…
  • 2017 American Transplant Congress

    AAV8 Delivery of TIMP-1 Prevents Hepatocyte Apoptosis After Liver Ischemia/Reperfusion Injury.

    S. Duarte, P. Matian, M. Miller, R. Busuttil, A. Coito.

    Dumont-UCLA Transplant Center, Los Angeles

    Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…
  • 2017 American Transplant Congress

    Disparity in Transplant Referral Patterns Based on Physician Dependent Variables.

    V. Loy, A. Rzepczynski, S. Bello, C. Blackburn, A. Lu.

    Loyola University Medical Center, Maywood, Il

    Introduction: Distance from a liver transplant (LT) center does not affect outcomes; however, rural areas have lower rates of listing and receiving solid organ transplants.…
  • 2017 American Transplant Congress

    This is Why We Can't Have Nice Things- Real World Experience with Everolimus in Livers.

    C. Perez,1 J. Fleming,1 M. Sell,1 B. O'Brien,1 A. Rogers,1 I. Lee,1 C. Mardis,1 A. Mardis,1 N. Patel,1 H. Meadows,1 N. Pilch,2 K. Chavin,2 D. Dubay,2 D. Taber.2

    1Pharmacy, Medical University of South Carolina, Chareleston, SC; 2Surgery, Medical University of South Carolina, Charleston, SC

    Purpose: To determine if discontinuation rates of everolimus (RAD) in clinical practice is higher than the 30% demonstrated in trials.Methods: This was a retrospective cohort…
  • 2017 American Transplant Congress

    Hepatic Ischemia Reperfusion Injury After Liver Transplantation Is Associated with Acute Kidney Injury.

    S. Kubal,1 M. Anderson,2 J. Fridell,1 B. Ekser,1 T. Taber,2 P. Li,1 M. Ghabril,3 M. Lacerda,3 R. Mangus.1

    1Department of Surgery, Division of Transplantation, Indiana University School of Medicine, Indianapolis, IN; 2Department of Nephrology, Indiana University School of Medicine, Indianapolis, IN; 3Department of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN

    Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that severity of IRI correlates with…
  • 2017 American Transplant Congress

    Effects of the Gut-Liver Axis on Ischemia-Mediated Hepatocellular Carcinoma Recurrence in the Mouse Liver.

    L. Orci,1 S. Lacotte,1 V. Delaune,1 G. Oldani,1 F. Slits,1 C. Rossetti,2 L. Rubbia-Brandt,3 P. Morel,1 C. Toso.1

    1Hepato-pancreato-biliary Centre, Department of Surgery, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland; 2Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell'Insubria, Varese, Italy; 3Division of Clinical Pathology, Department of Pathology and Immunology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland

    Background: There is growing evidence that liver graft ischemia-reperfusion (I/R) is a risk factor for hepatocellular carcinoma (HCC) recurrence after liver transplantation, but the involved…
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