2018 American Transplant Congress
Biochemistry Profiles Following Pig-to-Nonhuman Primate Liver Xenotransplantation
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Objectives:Clinical progress in liver transplantation has increased the demand for organs, however, supply remains stagnant. Porcine liver xenotransplantation (LXT) would help address this imbalance. Here…2018 American Transplant Congress
Glycogen Synthase Kinase 3 beta Regulates Liver Inflammation Activation and Resolution by Controlling AMPK Activities
Background & Aims: Glycogen synthase kinase 3β (Gsk3β) is ubiquitously expressed with distinctive functions in different types of cells. Although its roles in regulating innate…2018 American Transplant Congress
Offer Acceptance Practices and Geographic Variability in Allocation MELD at Transplant
1SRTR, Minneapolis; 2U.S. Navy, Anapolis.
Offer acceptance practices may cause geographic variability in allocation model for end-stage liver disease (aMELD) score at transplant and could magnify the apparent impact of…2018 American Transplant Congress
A Six-Month, Prospective, Single-Center, Pilot Study to Determine the Pharmacokinetics and Effectiveness of Immunosuppressant Regimens in Liver Transplantation Patients Receiving Twice-Daily Tacrolimus and Everolimus (TAC + EVR BID) Regimen Converted to Once-Daily Tacrolimus and Everolimus (TAC + EVR QD) Regimen – A Priliminary Report
Adherence to immunosuppressant regimen is crucial for graft survival and usually inversely related to the dose frequency. Similar efficacy and safety profile has been approved…2017 American Transplant Congress
MELD-Based Allocation Leads to Inferior Survival After Liver Transplantation.
Department of Surgery, Campus Virchow and Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany
Introduction and BackgroundThe MELD-based allocation system has been implemented in Germany in 2006 in order to decrease waiting list mortality in patients with end stage…2017 American Transplant Congress
Neutering Worsens Liver Ischemia/Reperfusion Injury in Both Male and Female Mice.
Introduction: Ischemia/reperfusion injury (IRI) causes significant morbidity in liver transplantation and other surgical scenarios. A better understanding of the molecular mechanisms of IRI is required…2017 American Transplant Congress
A Pilot Test of the "Individualized Self-Management Training in Adolescent/Young Adult Recipients of Transplantation (iSTART)" Program.
University of Michigan, Ann Arbor
Objective: To pilot test the feasibility and impact of the iSTART program on medication adherence, quality of life, and medication barriers among adolescent/young adult (AYA)…2017 American Transplant Congress
PPAR-γ Agonist Attenuates Hepatic Ischemia-Reperfusion Injury in a Mouse Model by Regulating Kupffer Cell Polarization.
PPAR-γ agonists have shown protective effect on ischemia-reperfusion injury (IRI) in cerebral and renal tissue. The effects of PPAR-γ on hepatic IRI is unclear. We…2017 American Transplant Congress
Use of Ledipasvir/Sofosbuvir with or without Ribavirin in Patients Post-Liver Transplant: Evaluation of Real-World Datasets.
PURPOSE: Post-liver transplant(LT) patients with HCV are considered a difficult-to-treat population. Ledipasvir/sofosbuvir(LDV/SOF) +ribavirin(RBV) for 12 weeks is approved in GT1 LT recipients based on the…2017 American Transplant Congress
Protective Effect of Crepidiastrum denticulatum Extract Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.
Crepidiastrum denticulatum (CD) is a well-known, traditionally consumed vegetable in Korea, which was recently reported to have bioactive compounds with detoxification and antioxidant properties. Ischemia-reperfusion…
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