2018 American Transplant Congress
Poverty, End Stage Liver Disease, and Transplantation in Georgia
1Surgery, Emory University, Atlanta, GA; 2Medicine, University of Pennsylvania, Philadelphia, GA.
Background: Though discussions of equity in liver transplantation remain focused primarily on relative availability of allografts as a measure of access, differences in disease burden…2018 American Transplant Congress
Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver Resident Macrophage M2 Polarization via C/EBP-Homologous Protein-Mediated Endoplasmic Reticulum Stress
Anesthesiology, First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Background:Aggravated liver ischemia and reperfusion (IR) injury has been observed in hyperglycemic hosts, but its underlying mechanism remains undefined. The aim of the study was…2018 American Transplant Congress
Cumulative United States Experience in Domino Liver Transplants
Surgery, State University of New York, Downstate, Brooklyn, CA.
Background/Purpose: The ongoing shortage of livers in the setting of growing waiting lists remains a challenge in transplantation. First introduced in 1995, sequential or domino…2018 American Transplant Congress
Liver Transplantation as a Life Saving Procedure after Post Resection Liver Failure and Iatrogenic Liver Injuries
Introduction: Iatrogenic injuries to vital structures of the liver and liver failure post liver resection are both associated with high mortality. Selected patients that were…2018 American Transplant Congress
Gr1– Macrophages Play Critical Roles in Liver Inflammation Resolution after IRI via Efferocytosis
Inflammation resolution is an integral part of liver ischemia reperfusion injury (IRI), which affects not only the severity of tissue damage, but more importantly its…2018 American Transplant Congress
Liver Allocation: One OPO's Experience with Expedited versus Non-Expedited Placement
LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK.
Background: One organ procurement organization (OPO) sought to study expedited versus non-expedited livers recovered/transplanted after local/regional centers declined. The OPO sought to determine relative recipient…2018 American Transplant Congress
Effects of Preformed Antibody on Survival Following Pig-to-Primate Liver Xenotransplantation
Transplant Surgery, Massachusetts General Hospital, Boston, MA.
Objectives:Xenotransplantation represents the best near-term solution to address the current organ shortage. We have developed a pre-clinical model of pig-to-primate liver xenotransplantation (LXT), and now…2018 American Transplant Congress
TGR5-Mediated AMPK/mTOR Signaling Regulates Macrophage Migration and Polarization in Liver Ischemia Reperfusion
Background: Although the plasma membrane-bound G protein–coupled bile acid receptor (TGR5) exerts protective roles in various inflammatory diseases, little is known about the effects and…2018 American Transplant Congress
MELD Based Allocation Deteriorates Patient Survival without Improving Waiting List Mortality in a Low Donor Area
The MELD-based allocation system has been implemented in Germany in 2006 in order to decrease waiting list mortality in patients with end stage liver disease.…2018 American Transplant Congress
Assessment of Bile Production and Quality during Normothermic Ex Vivo Liver Perfusion to Predict Biliary Injury
Background. Liver transplantation (LT) with donation after circulatory death (DCD)-grafts is associated with higher risk for biliary strictures. We evaluated bile production and quality during…
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