2017 American Transplant Congress
Alcohol-Induced Hepatic Cirrhosis Is Rising Among Young Adults.
Background: Alcoholic cirrhosis is a common indication for liver transplantation. Recent population studies have shown no change in the overall prevalence of alcohol use, but…2017 American Transplant Congress
Impact of Inflammatory Bowel Disease on Survival and Risk of Retransplantation of Primary Sclerosing Cholangitis Patients Following Liver Transplantation: UNOS Data Analysis.
Background: The impact of inflammatory bowel disease (IBD) on outcomes after liver transplantation (LT) for primary sclerosing cholangitis (PSC) has been inconclusive. Previous reports suggested…2017 American Transplant Congress
Graft and Patient Survival in Liver Transplantation for Primary Sclerosing Cholangitis with Organs from DCD versus DBD Donors: Analysis of the UNOS Database.
Background: Primary sclerosing cholangitis (PSC) remains a major indication for liver transplantation (LT) worldwide. In an era of limited organ donation pool, assessment of PSC…2017 American Transplant Congress
Addition of hEPCR.hCD55.hTFPI.hCD47 Modulates Multi-Lineage Cell Sequestration and Coagulation Activation by GalTKO.hCD46 Transgenic Pig Livers Perfused Ex Vivo with Human Blood.
PurposeThe sequestration of multiple hematopoietic cell lineages and inappropriate coagulation cascade activation is associated with poor outcomes in multiple liver xenotransplant models. Here we evaluate…2017 American Transplant Congress
Evaluation of Low Dose Valganciclovir for the Prevention of Cytomegalovirus in Liver Transplant Recipients.
BACKGROUND: Cytomegalovirus (CMV) causes significant morbidity and mortality following orthotopic liver transplantation (OLT). Valganciclovir (VGCV) is used to prevent CMV, but at labeled doses can…2017 American Transplant Congress
Geographic Differences in Secular Trends of Liver Supply and Demand.
1JHU, Baltimore; 2US Naval Academy, Annapolis
Geographic disparities in access to deceased donor liver transplant reflect geographically disparate levels of supply of and demand for organs. Proposed policy changes like redistricting…2017 American Transplant Congress
“Donor Age or Quality” a Qualitative Analysis of Livers Declined for 830.
Abdominal Transplant, University of Rochester Medical Center, Rochester, NY
Background: Efforts to improve organ utilization have been hindered by a lack of specificity on center's reasons for declining organs. One of the most frequently…2017 American Transplant Congress
Outcomes Following Colectomy in Liver Transplant Recipients.
Liver transplant recipients (LTR), like the general population, often require surgical procedures for non-transplant related issues. Given the need for immunosuppression and the physiologic impact…2017 American Transplant Congress
Outcomes of Moderately to Severely Steatotic Grafts in Liver Transplantation: A Meta-Analysis.
1Mayo Clinic, Rochester; 2Bassett Medical Center, Cooperstown
Background/Objectives:There is a worldwide need to expand the pool of available liver grafts. Livers with >50% steatosis are discarded for orthotopic liver transplantation (OLT) by…2017 American Transplant Congress
Long-Term Liver and Kidney Survival Following Combined Liver-Kidney Transplantation, with or without Preformed Donor-Specific Antibodies.
Introduction: Successful kidney transplantation despite a positive crossmatch is well known after combined liver-kidney transplantation (CLKT). However, recently, concerns regarding the impact of preformed anti-HLA…
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