Articles tagged "Liver"

2019 American Transplant Congress
Partial Freezing: Subzero Whole Liver Preservation In The Presence Of Ice
S. E. Cronin¹, C. A. Pendexter¹, R. J. deVries¹, S. Kimura², S. Ozer¹, P. D. Banik¹, S. Nagpal¹, H. Yeh², S. N. Tessier¹, K. Uygun¹, M. Toner¹
¹Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, ²Transplant Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA
*Purpose: We aim to develop a protocol to bank organs for several days, enabling global organ matching and potentially the utilization of organs unusable with…
2019 American Transplant Congress
IgG4 Subclass Class 2 Donor Specific Antibody (DSA) is Associated with Subclinical Rejection in Stable Pediatric Liver Transplant (LT) Recipients with Normal Liver Tests
A. Jackson¹, S. Kanaparthi², B. Burrell³, D. Lucas⁴, R. Vega⁴, A. J. Demetris⁵, S. Feng⁶
¹Surgery, Duke University, Durham, NC, ²The Immune Tolerance Network, Bethesda, MD, ³Immune Tolerance Network, Bethesda, MD, ⁴Medicine, Johns Hopkins University, Baltimore, MD, ⁵Pathology, University of Pittsburgh, Pittsburgh, PA, ⁶Surgery, University of California San Francisco, San Francisco, CA
*Purpose: DSA is a known biomarker of allograft rejection, yet injury phenotype and potential differ across organs. Among pediatric LT recipients entering iWITH (NCT01638559), an…
2019 American Transplant Congress
Disparities in Pediatric Liver Transplant Waitlist Access
S. C. Kim¹, K. Ross¹, E. Hsu², R. Patzer¹, R. J. Lynch¹
¹Emory University, Atlanta, GA, ²University of Washington, Seattle, WA
*Purpose: While disparities in access to liver transplant are well documented among adults, differences in access to the waitlist for children in remote or underserved…
2019 American Transplant Congress
Contribution of CD38 to Methionine Choline Deficient (MCD) Diet-Induced Liver Injury in Rats
J. Kim, Y. Lee, B. F. Reader, C. Akateh, K. R. Maynard, K. W. Washburn, J. L. Zweier, B. A. Whitson, S. M. Black
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: Nonalcoholic fatty liver disease (NAFLD) and associated non-alcoholic steatohepatitis (NASH) is a rising cause of end stage liver disease, increasing the need for liver…
2019 American Transplant Congress
Hepatic Artery Anastomosis Post-Operative Anatomy Influences Doppler Ultrasound Systolic Acceleration Time after Liver Transplantation
R. A. Choudhury, A. Yule, K. Conzen, E. A. Pomfret, T. L. Nydam
Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Prolongation of the systolic acceleration time (SAT) and decreased resistive index (R/I) of the proper hepatic artery following liver transplant have been associated with…
2019 American Transplant Congress
What Do We Not Know about Long Term Liver Transplant Patients? A Look at Side Effect Burden and Medication Adherence
K. Foster¹, C. Perez¹, T. Harrison¹, H. Corbo¹, N. Patel¹, D. Taber¹, H. Meadows¹, J. Fleming¹, D. DuBay², J. McGillicuddy², N. Pilch¹
¹Department of Pharmacy Services, -Medical University of South Carolina, -Charleston, SC, ²Division of Transplant Surgery, Department of Surgery, -Medical University of South Carolina, -Charleston, SC
*Purpose: Historically our focus in transplantation has been on 1 year patient and graft outcomes. With the proposed shifts in legislation and the more recent…
2019 American Transplant Congress
Molecular Analysis of Rejection and Injury in Human Liver Transplant Biopsies: First Results of the INTERLIVER Study
P. F. Halloran and The INTERLIVER Study Group
University of Alberta, Edmonton AB, AB, Canada
*Purpose: The relationship of histologic liver transplant biopsy assessments to actual rejection and injury is unclear. Recent progress in molecular reclassification of kidney, heart, and…
2019 American Transplant Congress
Hepatitis C Treatment and Transplant Outcomes in Liver Transplant Recipients with Hepatitis C Positive Donors
I. Booth, J. Clark, J. C. LaMattina, A. Haririan, R. N. Barth, B. Ravichandran
University of Maryland Medical Center, Baltimore, MD
*Purpose: With direct-acting antivirals for hepatitis C virus (HCV), transplant centers have expanded the donor pool with positive short term outcomes with early HCV treatment.…
2019 American Transplant Congress
No Plan is a Bad Plan! Results of the American Society of Transplantation (AST) Living Donor Community of Practice Mortality Workgroup Survey on Disaster Planning Following a Living Donor Death
M. L. Henderson¹, S. E. Van Pilsum Rasmussen¹, M. M. Waldram¹, K. L. Lentine², D. A. Mandelbrot³, R. L. Hays³, D. G. Maluf⁴, M. Cooper⁵
¹Johns Hopkins, Baltimore, MD, ²Saint Louis University, St Louis, MO, ³University of Wisconsin, Madison, WI, ⁴University of Tennessee, Memphis, TN, ⁵Georgetown University, Washington, DC
*Purpose: The risk of perioperative mortality following living kidney and liver donation, although extremely low, must not be considered a ‘never event’. While the risks…
2019 American Transplant Congress
Sensitivity of 5-Tier System to Unadjusted Confounding
N. Salkowski, A. Wey, J. Snyder
SRTR, Minneapolis, MN
*Purpose: The Scientific Registry of Transplant Recipients (SRTR) fits risk-adjusted models for its semiannual program-specific reports (PSRs). Although SRTR adjusts for as many important risk…