Articles tagged "Liver"

2019 American Transplant Congress
National Landscape of Donors Allocated through the Hope Act in the United States
A. R. Wilk¹, R. Hunter², M. A. McBride², D. K. Klassen²
¹Research, United Network for Organ Sharing, Richmond, VA, ²United Network for Organ Sharing, Richmond, VA
*Purpose: To address the shortage of donor organs and to increase transplantation opportunities for HIV+ recipients, the HIV Organ Policy Equity (HOPE) Act was enacted…
2019 American Transplant Congress
Simulated Tier Variability
N. Salkowski, A. Wey, J. Snyder
SRTR, Minneapolis, MN
*Purpose: The Scientific Registry of Transplant Recipients semi-annually assigns transplant programs to one of five performance tiers for 1-year graft survival in its program-specific reports…
2019 American Transplant Congress
Comparison of Proton Pump Inhibitors versus Histamine-2-Receptor Antagonists on Clostridium difficile Rates in Liver Transplant Recipients
S. Wiehe, K. Roach, A. Qamar
Lahey Hospital and Medical Center, Burlington, MA
*Purpose: To determine if there is a difference in 90 day Clostridium difficile infection (CDI) rates before and after the stress ulcer prophylaxis (SUP) protocol…
2019 American Transplant Congress
Metabolic Liver Transplantation – Can We Afford It?
N. Yazigi¹, W. Fujiwara²
¹Transplant Institute, MedStar Georgetown University Hospital, Washigton, DC, ²Georgetown University Medical School, Washigton, DC
*Purpose: Despite major improvement in medical and nutritional care of pediatric patients suffering from intoxication inherited metabolic disorders, their long term outcomes remain guarded. Liver…
2019 American Transplant Congress
Lower Alcohol Taxes Are Associated with Increased Liver Transplant Listing
N. T. Shen¹, M. Raver¹, N. Hutchison¹, A. Jesudian¹, J. Bray², B. Schackman³, R. S. Brown¹
¹Medicine; Division of Gastroenterology and Hepatology, New York Presbyterian Hospital - Weill Cornell, New York, NY, ²Economics, University of North Carolina at Greensboro, Greensboro, NC, Greensboro, NC, ³Healthcare Policy and Research, Weill Cornell Medicine, New York, NY
*Purpose: Alcoholic liver disease (ALD) is a leading indication for liver transplantation worldwide with rising prevalence. Whether relationships exist between transplant listing for ALD and…
2019 American Transplant Congress
Digital Imaging Software vs. the “Eyeball” Method in Quantifying Steatosis in a Liver Biopsy
J. Long¹, J. Motter¹, S. Besharati¹, S. Jerman², R. Anders¹, A. Ortiz², D. Bowman², T. Dunn³, D. Lee⁴, A. Massie¹, R. Barth⁵, B. Philosophe¹
¹Johns Hopkins, Baltimore, MD, ²Indica Labs, Corrales, NM, ³UPenn, Philadelphia, PA, ⁴Mayo Clinic, Jacksonville, FL, ⁵University of MD, Baltimore, MD
*Purpose: The use of steatotic livers is controversial, but may represent an underutilized resource to increase the donor pool. Although
2019 American Transplant Congress
The Impact of Pneumonia after Liver Transplant
N. M. Theodoropoulos, P. Mahboub, A. Bozorgzadeh
University of Massachusetts Medical School, Worcester, MA
*Purpose: Infection is a major cause of morbidity and mortality after organ transplantation and pneumonia is one of the most frequently encountered infections.*Methods: We conducted…
2019 American Transplant Congress
Metabolic Liver Transplant: A Single Cooperative 2002-2017
N. Yazigi¹, K. Chapman²
¹Transplantation, MedStar Georgetown University Hospital, Washigton, DC, ²Transplantation, Children's National Rare Disease Institute, Washington, DC
*Purpose: Liver transplant (LT) can increase quality and quantity of life for patients with inherited metabolic diseases (IMDs) who suffer severe and unpredictable complications despite…
2019 American Transplant Congress
Multicenter Experience Evaluating Outcomes of HCV-Seropositive Donors to HCV-Seronegative Recipients Liver Transplantation
K. Wijarnpreecha¹, B. Aqel², S. Pungpapong¹, C. Taner³, K. Reddy⁴, M. Leise⁵, R. Dickson²
¹Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, ²Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, ³Transplant, Mayo Clinic, Jacksonville, FL, ⁴Transplant and Hepatobiliary Surgery, Mayo Clinic, Scottsdale, AZ, ⁵Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN
*Purpose: Grafts from hepatitis C virus (HCV)-seropositive donors can now be considered for liver transplant (LT) due to the advent of direct-acting antiviral agents (DAA).…
2019 American Transplant Congress
Impact of Liver Recipient Genotype on Tacrolimus
S. Tremblay¹, T. Fukuda², T. Mizuno², A. A. Vinks², E. Woodle¹, J. Klawitter³, J. Klawitter³, U. Christians³, R. R. Alloway¹
¹University of Cincinnati, Cincinnati, OH, ²Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ³iC42 Clinical Research and Development, Aurora, CO
*Purpose: In kidney transplant recipients, recipient genotype (CYP3A5 *3) has the greatest influence on tacrolimus pharmacokinetics (PK). However, in liver transplant recipient, donor liver and…