Articles tagged "Liver"

2020 American Transplant Congress
MY-ATLAS: A Novel Simulation Algorithm for Liver Transplant Allocation
C. G. Rickert¹, H. Zhao², Z. Leung², M. Akan³, J. F. Markmann¹, S. Tayur³, H. Yeh¹
¹Surgery, Massachusetts General Hospital, Boston, MA, ²City University of Hong Kong, Hong Kong, China, ³Tepper School of Business, Carnegie Mellon University, Pittsburgh, PA
*Purpose: Currently, the primary tool for modeling expected outcomes from changes in allocation policy is the SRTR-run Liver Simulated Allocation Model (LSAM), which is neither…
2020 American Transplant Congress
Tetramethylpyrazine Activated Pparγ in Resuscitating the Liver Graft Donatedafter Cardiac Death
F. Zhen, F. Lin, Z. Lihua, L. Wenjin, X. Yan, C. Yong, Y. Qifa
Zhongnan Hospital of Wuhan University, Wuhan, China
*Purpose: to identify whether Tetramethylpyrazine (TMP) pretreatment can protect DCD grafts preserved during cold storage or/and HMP and transplanted.The protective mechanisms of TMP were also…
2020 American Transplant Congress
Liver Transplantation with Grafts from Super Obese Donors with a BMI>50
P. Vargas¹, J. M. Cullen¹, P. Northup², J. Oberholzer¹, S. Pelletier¹, N. Goldaracena¹
¹Department of Surgery, Division of Transplantation, University of Virginia Health System, Charlottesville, VA, ²Department of Medicine-Gastroenterology, University of Virginia Health System, Charlottesville, VA
*Purpose: Organ shortage is aggravated by an obesity epidemic. There is limited data on liver transplant (LT) outcomes from liver grafts originating from super obese…
2020 American Transplant Congress
Tolerant Liver Transplant Patients Have Higher Level of Y RNA Fragments in the Circulation
C. Kuscu¹, A. Wolen¹, A. Bajwa¹, C. Kuscu¹, J. Eason², B. Ramaswami³, D. Maluf¹, G. Mazariegos³, G. Chalasani³, V. Mas¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ³Thomas E. Starzl Transplantation Institute, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Tolerance post transplantation continue to be the ultimate goal in transplantation. Circulating small RNAs are one of the best candidates for biomarker studies. To…
2020 American Transplant Congress
Patient Reported Medication Nonadherence and Tolerability: Results of a Prospective Observational Study
D. Taber, N. Patel, K. Foster, F. Bartlett, C. Perez, H. Meadows, N. Pilch, A. Posadas, K. Soliman, V. Rao, M. Casey, V. Rohan, J. McGillicuddy, S. Nadig, D. Dubay
MUSC, Charleston, SC
*Purpose: Medication nonadherence (MNA) is a major contributor to late allograft loss in transplantation (txp). Immunosuppression therapy is highly effective at preventing rejection yet presents…
2020 American Transplant Congress
Pediatric National Liver Review Board: Impact on Children on the Waitlist
J. Foutz¹, S. Noreen¹, E. Hsu², E. Perito³, G. Mazariegos⁴
¹United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³UCSF Benioff Children's Hospital, San Francisco, CA, ⁴Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: On 5/14/19 changes were made to the exceptions review process for pediatric liver transplant candidates, with transition from 11 Regional Review Boards to one…
2020 American Transplant Congress
The Link between Waitlist Mortality and Access to Transplant, an Imaginative Reality
R. Batra¹, D. Mulligan¹, D. Haakinson¹, S. Noreen², D. Stewart², G. Gan³, Y. Deng³, S. Kulkarni¹
¹Surgery, Yale University School of Medicine, New Haven, CT, ²UNOS, Richmond, VA, ³Yale University, New Haven, CT
*Purpose: Liver transplant waitlist mortality due to inadequate access to livers is the Achilles heel in liver transplantation in United States. This remains amongst the…
2020 American Transplant Congress
The Effect of Expanding Utilization of Living Donor Liver Transplantation tn the United States
K. N. Wanis¹, A. Sarvet¹, M. J. Stensrud¹, B. Al-Judaibi², K. Tomiyama³, R. Hernandez-Alejandro³
¹Epidemiology, Harvard School of Public Health, Boston, MA, ²Division of Transplantation, University of Rochester, Rochester, NY, ³Division of Transplantation/Hepatobiliary Surgery, Department of Surgery, University of Rochester, Rochester, NY
*Purpose: We estimated the effect that expansion of living donor liver transplantation (LDLT) would have on mortality for individuals added to the waitlist.*Methods: Using data…
2020 American Transplant Congress
A Single-Center Experience in Transfusion-Free Liver Transplantation: Referrals and Outcomes from 2005 to 2019
B. H. Horwich¹, A. Mulgaonkar¹, B. Kim², N. Kaur¹, J. Kahn², Y. Genyk³, A. Ahearn³, H. Han²
¹Internal Medicine, University of Southern California, Los Angeles, CA, ²GI & Liver Diseases, University of Southern California, Los Angeles, CA, ³Surgery, University of Southern California, Los Angeles, CA
*Purpose: The Jehovah’s Witnesses is a religious group known to the medical community for its non-acceptance of blood products. This poses a significant challenge in…
2020 American Transplant Congress
Development and Characterization of Decellularized Whole Human Livers for Increasing Donor Pool
A. Acun, R. Oganesyan, B. E. Uygun
Massachusetts General Hospital - Harvard Medical School, Boston, MA
*Purpose: Liver diseases are recognized as the second leading cause of mortality amongst all digestive diseases in the United States. Orthotopic liver transplantation leads to…