Articles tagged "Liver"

2021 American Transplant Congress
Validation of PROMIS Anxiety Computer Adaptive Test in Solid Organ Transplant Recipients
M. Saqib, M. Yang, F. Jamal, S. Aghamohammadi, G. Ahmadzadeh, M. Hamid, V. Shah, N. Jayakumar, M. Novak, I. Mucsi
University Health Network, Toronto, ON, Canada
*Purpose: To assess the validity and reliability of the PROMIS Anxiety item bank administered using Computer Adaptive Test (PROMIS-A CAT) in patients who received solid…
2021 American Transplant Congress
The Survival Benefits of Using Marginal Allografts in Liver Transplantation
T. H. Malik¹, E. L. Godfrey¹, A. Rana²
¹Baylor College of Medicine, Houston, TX, ²Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Our study assessed whether using marginal allografts at initial time of listing provided similar or greater survival benefit versus waiting on the transplant waitlist…
2021 American Transplant Congress
Liver Dysfunction Following Lung Transplantation
E. J. Hyzny¹, E. G. Chan¹, J. P. Ryan¹, T. Harano¹, M. R. Morrell², P. G. Sanchez¹
¹Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, ²Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To describe the incidence and risk factors for postoperative hepatic dysfunction (POHD) following lung transplantation (LT) and long-term outcomes for these patients.*Methods: We performed…
2021 American Transplant Congress
Epigenetic & Functional Changes Associated with Alloreactive Memory CD8 T Cell Subsets in Liver Transplant Patients
H. Abdelsamed¹, S. Liu¹, M. Juya¹, D. Metes², F. Lakkis¹, A. Thomson¹
¹University of Pittsburgh Medical Center, Pittsburgh, PA, ²UPMC, Pittsburgh, PA
*Purpose: Donor-specific allo-reactive memory CD8 T cells play a pivotal role in allo-immunity and represent a major hurdle against tolerance induction in solid organ transplantation.…
2021 American Transplant Congress
Early Hypertransaminasemia in Kidney Transplant Recipient: Influence of Donor Type and Clinical Significance
E. Solà-Porta, M. Redondo-Pachón, S. Núñez-Delgado, C. Arias-Cabrales, M. Mir, A. Buxeda, C. Burballa, M. Crespo, J. Pascual, M. Pérez-Sáez
Nephrology, Hospital del Mar, Barcelona, Spain
*Purpose: The increase in transaminases after kidney transplant (KT) is frequent. Although the cause is unknown, it has been associated with factors such as immunosuppression,…
2021 American Transplant Congress
When One Size Does Not Fit All: Geographically Heterogeneous Liver Distribution
M. A. Mankowski¹, S. Gentry², D. Segev³, N. Trichakis⁴
¹KAUST, Thuwal, Saudi Arabia, ²US Naval Academy, Annapolis, MD, ³JHU, Baltimore, MD, ⁴MIT, Boston, MA
*Purpose: The new liver allocation system prioritizes distribution within acuity circles, instead of within DSAs. Acuity circles have the same radius around all donor hospitals…
2021 American Transplant Congress
Influence of Frailty on Psychometric Factors and Health-related Quality of Life in Patients on the Waitlist for Liver Transplantation
C. G. Klein, J. Latuske, E. Malamutmann, A. Paul, A. Oezcelik
University Medicine Essen, Essen, Germany
*Purpose: The aim of this prospective study was to evaluate the influence of frailty on depression, anxiety and health-related quality of life for patients on…
2021 American Transplant Congress
Human Liver-derived Mesenchymal Stromal Cells (MSC) are Superior Inhibitors of Natural Killer Cells Compared to Bone Marrow or Adipose Tissue-derived MSC
F. Yigitbilek, M. J. Hansen, W. D. Park, M. D. Stegall, T. Taner
Mayo Clinic, Rochester, MN
*Purpose: Guided by the liver allografts’ unique tolerogenic microenvironment and the immunoprotective impact on simultaneously transplanted organs, we recently isolated liver mesenchymal stromal cells (L-MSC)…
2021 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis by Single-nucleus Rna Sequencing
C. Kuscu¹, C. Kuscu¹, M. Akram², A. Shetty³, D. G. Maluf⁴, J. Eason¹, V. Mas⁵
¹Surgery, James D Eason Transplat Institute, Memphis, TN, ²Surgery, Center for Biomedical Informatics, Memphis, TN, ³Surgery, Institute for Genome Sciences, School of Medicine, Baltimore, MD, ⁴Surgery, Program in Transplantation University of Maryland, Baltimore, MD, ⁵Surgery, Division of Surgical Science University of Maryland, Baltimore, MD
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is characterized by metabolic syndrome and the accumulation of fat in the liver cells (hepatocytes) leading to inflammation and…
2021 American Transplant Congress
Clearance of Viral RNA and DNA and Antibody Response Following Administration of Live Attenuated Measles and Varicella Vaccines in Children with Chronic Liver Disease
S. Kemme¹, A. Weinberg², A. G. Feldman¹
¹Children's Hospital Colorado, Denver, CO, ²University of Colorado Denver, Denver, CO
*Purpose: Guidelines recommend waiting four weeks between live vaccine administration and transplantation; however, there is little data to support this waiting period and it often…