2019 American Transplant Congress
Notch1 Signaling Protects Liver Grafts from Ischemia Reperfusion Injury: From Mouse to Human
Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: The clinical relevance and tissue-specific role of Notch1 activation, a highly conserved transmembrane receptor involved in cell fate decision, proliferation and regeneration, in orthotopic…2019 American Transplant Congress
Pathologic Vascular Invasion Correlates with Worse Outcome in Hepatoblastoma Patients Treated with Liver Transplantation – A Hepatoblastoma Transplant Consortium Study
*Purpose: Orthotopic liver transplant (OLTx) is the most common method to treat unresectable hepatoblastoma (HB) in children. There is limited data focusing on the outcomes…2019 American Transplant Congress
Prevention of Graft Ischemia-Reperfusion Injury in Ischemia-Free Liver Transplantation
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Graft ischemia-reperfusion injury (IRI) is an inevitable event in organ transplantation, which often leads to a number of complications and even patient deaths. We…2019 American Transplant Congress
Liver Transplant Candidate Attitudes towards Organs from Increased Risk Donors: A Single Center Survey
University Health Network, Toronto, ON, Canada
*Purpose: Increased Risk Donors (IRDs) are a significant proportion of the deceased organ donor pool but may be declined by patients on the liver transplant…2019 American Transplant Congress
Discard Patterns in Donors with Non Alcoholic Fatty Liver Disease
*Purpose: Obesity and nonalcoholic fatty liver disease (NAFLD) are major health issues affecting 20-50% of the US adult population and are increasingly prevalent in potential…2019 American Transplant Congress
A Randomized Controlled Clinical Trial of Thymoglobulin® and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation: A Multicenter Study
*Purpose: Thymoglobulin® (r-ATG) has been used as induction therapy in liver transplantation (LT). No prospective, randomized, controlled, trial (RCT) has been performed to evaluate effect…2019 American Transplant Congress
Graft TIM4 Deficiency Protects Liver from Ischemia Reperfusion Injury: From Mouse to Human
*Purpose: Liver ischemia-reperfusion injury (IRI) is a major risk factor for early graft dysfunction and rejection in orthotopic liver transplantation (OLT). We and others have…2019 American Transplant Congress
Outcomes of En Bloc Simultaneous Liver-Kidney Transplantation Compared to the Traditional Technique
University of Cincinnati, Cincinnati, OH
*Purpose: Simultaneous liver-kidney transplantation (SLKT) is indicated for patients with end-stage liver disease (ESLD) and concurrent renal insufficiency. En bloc SLKT has been reported as…2019 American Transplant Congress
Portal Vein Thrombosis Discovered at Liver Transplant: Barrier to Success
*Purpose: Portal vein thrombosis (PVT) present at listing or diagnosed while listed enables potential treatment pre-liver transplant (OLT). Main PVT at OLT (mPVT) complicates surgeries…2019 American Transplant Congress
Viability Testing and Transplantation of Marginal Donor Livers (VITTAL) Trial Outcomes: Proteomic Analysis of Perfusates from Livers Undergoing Normothermic Machine Liver Perfusion Reveals Biomarkers Predictive of Graft Viability and Post-Transplant Complications
*Purpose: The VITTAL clinical trial demonstrated that post-ischaemic normothermic machine perfusion(NMP) can increase utilisation of livers from the marginal pool of extended criteria donors (ECD).…
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