Articles tagged "Liver transplantation"

2019 American Transplant Congress
B7H1 Expression is Crucial for Tolerance Induction in Mouse Liver Transplantation
M. Morita¹, S. Datta¹, C. Miller², T. Hamilton¹, K. Hashimoto³
¹Inflammation & Immunity, Lerner Research Institution, Cleveland, OH, ²General surgery, Liver Transplant Center, Cleveland Clinic, Cleveland, OH, ³General Surgery, Liver Transplant Center, Cleveland Clinic, Cleveland, OH
*Purpose: Following organ transplantation, lifelong immunosuppressive treatment is required and it causes severe side effects. Induction of donor specific tolerance is ideal, which actually spontaneously…
2019 American Transplant Congress
Early Use of Everolimus Plus Reduced Tacrolimus vs Standard Tacrolimus in De Novo Livertransplant Recipients: 12 Months Efficacy and Safety Data from HEPHAISTOS Study
B. Nashan¹, P. Schemmer¹, H. Schlitt¹, A. Pascher¹, C. Klein¹, U. Neumann¹, I. Kroeger², P. Wimmer², F. Braun¹
¹Study Group, Hephaistos, Germany, ²Novartis Pharma GmbH, Nuernberg, Germany
*Purpose: The HEPHAISTOS study was set up to compare early use of everolimus [EVR] combined with reduced tacrolimus [rTAC] versus standard-dose tacrolimus [TAC-C) in de…
2019 American Transplant Congress
Transplant Center Practices Are the Primary Drivers of United States Donation after Circulatory Death Liver Transplantation
L. Beal¹, D. T. Nguyen², T. Menser³, S. Zajac¹, E. A. Graviss², M. J. Hobeika¹
¹Department of Surgery, Houston Methodist Hospital, Houston, TX, ²Department of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, TX, ³Center for Outcomes Research, Houston Methodist Research Institute, Houston, TX
*Purpose: We hypothesize that a few high-utilization donation after circulatory death (DCD) liver centers are the primary drivers of the dissimilar rates of DCD liver…
2019 American Transplant Congress
The Outcomes after an Infection in Older Liver Transplant Recipients is Comparable to Younger Adults
J. Garcia-Diaz¹, M. Kerkelis², T. Shah³, M. Tucker⁴, M. Gastanaduy⁵, J. Woo¹, M. Ponder¹, M. Malinis⁶, M. Malinis⁶
¹Infectious Diseases, Ochsner Medical Center, New Orleans, LA, ²University of Queensland/Ochsner Clinical School, New Orleans, LA, ³Internal Medicine, St. Joseph Hospital, Denver, CO, ⁴Internal Medicine, Yale School of Medicine, New Haven, CT, ⁵Center for Outcomes and Health Services Research, Ochsner Medical Center, New Orleans, LA, ⁶Infectious Diseases, Yale School of Medicine, New Haven, CT
*Purpose: Solid organ transplantation is being increasingly offered to older patients with concurrent chronic medical conditions such as cardiovascular, cerebrovascular, and renal disease. Risk of…
2019 American Transplant Congress
Pure Laparoscopic Donor Hepatectomy Based On Korean Multicenter Experience
K. Suh¹, S. Hong¹, G. Choi², K. Lee¹, C. D. Kwon², K. Kim³, S. Lee⁴, Y. Han⁵, J. Cho⁶, H. Han⁷
¹Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ²Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ³Surgery, , Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ⁴Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ⁵Surgery, Daegu Catholic University School of Medicine, Daegu, Korea, Republic of, ⁶Surgery, Seoul National University Bundang Hospital, Seongnam, Korea, Republic of, ⁷Surgery, Seoul National University Bundang Hospital,, Seongnam, Korea, Republic of
*Purpose: Due to increased experience and knowledge in laparoscopic surgery in the era of minimally invasive surgery, laparoscopic donor hepatectomy is also being increasingly performed…
2019 American Transplant Congress
Favorable Waitlist Outcomes in Patients with Alcoholic Liver Disease in the MELD-Na Era
M. Safwan, K. Collins, D. Moonka, S. Jafri, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai
Henry Ford Health System, Detroit, MI
*Purpose: Alcoholic liver disease (ALD) is a common indication for liver transplantation. Patients with ALD are often required to be abstinent for a period of…
2019 American Transplant Congress
De Novo Glomerulonephritis after Non Renal Abdominal Organ Transplantation
C. Farkas¹, R. B. Ettenger¹, J. Zuckerman², R. S. Venick³, P. Weng¹
¹Pediatric Nephrology, UCLA, Los Angeles, CA, ²Pathology, UCLA, Los Angeles, CA, ³Pediatric Gastroenterology, UCLA, Los Angeles, CA
*Purpose: Pediatric recipients of non renal abdominal organs may develop renal abnormalities of uncertain etiology. We describe for the first time de novo lupus-like glomerulonephritis…
2019 American Transplant Congress
Liver Transplant Centers Select Different Characteristics for Recipients and Deceased Donors: Implications for Patients When Choosing a Center
C. R. Schaffhausen¹, M. J. Bruin², S. Chu², D. Schladt¹, S. Chinnakotla³, J. R. Lake⁴, W. Kim⁵, S. W. Biggins⁶, J. J. Snyder⁷, B. L. Kasiske⁷, A. K. Israni¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, Minneapolis, MN, ³Department of Surgery, University of Minnesota, Minneapolis, MN, ⁴Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, MN, ⁵Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, ⁶Division of Gastroenterology, University of Washington, Seattle, WA, ⁷Scientific Registry of Transplant Recipients, Minneapolis, MN
*Purpose: When patients can choose the liver transplant center at which to establish care, a prior knowledge of center acceptance practices (of candidates and donors)…
2019 American Transplant Congress
Impact of a Short Duration, Narrow Spectrum Perioperative Antibiotic Prophylaxis Regimen on Multi-Drug Resistant Surgical Site Infections in Adult Orthotopic Liver Transplantation
M. John¹, K. Maguigan¹, D. Schain², E. Thomas³, P. Efron⁴, J. Nelson⁵
¹Pharmacy, UF Health Shands Hospital, Gainesville, FL, ²Infectious Diseases, UF Health Shands Hospital, Gainesville, FL, ³Transplant Surgery, University Health System, San Antonio, TX, ⁴Surgery, UF Health Shands Hospital, Gainesville, FL, ⁵Pharmacy, University Health System, San Antonio, TX
*Purpose: There is a paucity of data defining the optimal agent and timing of peri-operative antimicrobial prophylaxis in orthotopic liver transplantation (OLT). The purpose of…
2019 American Transplant Congress
Guideline Adherence for Secondary Prevention of Stroke and Atherosclerotic Cardiovascular Disease among Liver Transplant Recipients
P. T. Campbell¹, M. Kosirog¹, S. Montag², S. Connolly¹, A. Daud³, A. Das¹, S. Pine¹, D. Finn³, J. Levitsky¹, J. L. Holl⁴, D. M. Lloyd-Jones⁵, L. B. VanWagner⁶
¹Division of GI and Hepatology, Department of Medicine, Northwestern University, Chicago, IL, ²Department of Preventive Medicine, Northwestern University, Chicago, IL, ³Center for Healthcare Studies, Northwestern University, Chicago, IL, ⁴Department of Pediatrics and Center for Healthcare Studies, Northwestern University, Chicago, IL, ⁵Departments of Preventive Medicine and Medicine-Cardiology, Northwestern University, Chicago, IL, ⁶Division of GI and Hepatology, Department of Medicine and Department of Preventive Medicine, Northwestern University, Chicago, IL
*Purpose: Data about provider adherence to clinical practice guidelines for secondary prevention of stroke and atherosclerotic cardiovascular disease (ASCVD) among liver transplant recipients (LTRs), which…