Articles tagged "Liver transplantation"

2019 American Transplant Congress
Microscopic Hepatic Steatosis Prior to Liver Transplantation Influences Clinical Outcomes
K. Nakamura, H. Hirao, T. Ito, S. Kageyama, K. Kadono, K. J. Dery, J. Aziz, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski
Surgery, Liver Transplant, UCLA, Los Angeles, CA
*Purpose: Although liver transplantation (LT) has become a standard care for end-stage liver diseases, early allograft dysfunction (EAD) and rejection crises curtail the outcomes. Considering…
2019 American Transplant Congress
Donor Safety for Minimal Invasive Hepatectoy in Liver Transplantation: The Korean Organ Transplantation Registry
H. Yu, J. Yang, S. Ahn
Chonbuk National University Hospital, Jeonju, Korea, Republic of
*Purpose: This study evaluated the safety and effectiveness of minimal invasive living donor hepatectomy in comparison with conventional open procedure using Korean Organ Transplantation Registry…
2019 American Transplant Congress
Results from the LIVE-C Free Trial
J. N. Fleming¹, D. DuBay¹, N. L. Jonassaint², R. S. Satoskar³, K. D. Chavin⁴
¹Medical University of South Carolina, Charleston, SC, ²University of Pittsburgh Medical Center, Pittsburgh, PA, ³Medstar Georgetown Medical Center, Washington, DC, ⁴University Hospital, Cleveland, OH
*Purpose: Ledipasvir/sofosbuvir (LDV/SOF) in combination with ribavirin (RBV) has shown excellent results post-liver transplant. However, due to the poor tolerability of RBV, it is commonly…
2019 American Transplant Congress
Monitoring And Management Of Proteinuria Is Often Ignored In Patients Receiving mTOR Therapy Following Orthotopic Liver Transplantation
R. Kaur¹, O. Sadiq², M. Alimirah¹, F. Kumssa¹, A. Patel³, S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology, Henry Ford Hospital, Detroit, MI, ³Nephrology, Henry Ford Hospital, Detroit, MI
*Purpose: Use of mTOR inhibitors, such as Everolimus (EVL), in liver transplant (LT) patients continues to rise as the side effect profile becomes more evident.…
2019 American Transplant Congress
Preoperative Risk Factor-based Cardiac Catheterization Is Associated With Low Cardiac Morbidity And Mortality In Liver Transplant Patients
R. Rachwan¹, I. Kutkut¹, P. D. Bourdillon², L. R. Timsina³, M. Ghabril⁴, C. A. Kubal⁵, M. A. Lacerda⁶, R. S. Mangus⁵
¹Internal Medicine, Indiana University, Indianapolis, IN, ²Internal Medicine, Indiana University, Division of Cardiology, Indianapolis, IN, ³Department of Biostatistics, Indiana University, Indianapolis, IN, ⁴Internal Medicine, Indiana University, Division of Hepatology, Indianapolis, IN, ⁵Surgery, Transplant Division, Indiana University, Indianapolis, IN, ⁶Internal Medicine, Division of Hepatology, Indiana University, Indianapolis, IN
*Purpose: Mortality post-liver transplant historically was largely attributed to coronary artery disease (CAD). Current guidelines recommend screening with non-invasive modalities in patients with risk factors.…
2019 American Transplant Congress
Impact of Vancomycin-Resistant Enterococci Gut Colonization on Liver Transplant Outcomes
D. Chiang, T. C. Dingle, S. Belga, D. Kabbani, J. Walter, J. G. Abraldes, C. Cervera
University of Alberta, Edmonton, AB, Canada
*Purpose: Vancomycin-resistant enterococci (VRE) colonization is common in liver transplant candidates. In addition to the risk of invasive enterococcal infections, dominance of VRE colonization in…
2019 American Transplant Congress
Early Cognitive Improvement One Month after Liver Transplant Measured by the NIH Toolbox
M. Kim¹, J. D. Peipert², K. J. Reid¹, E. M. Liotta¹, M. B. Maas¹, D. R. Ganger³, P. C. Zee¹, D. P. Ladner⁴
¹Neurology, Northwestern University, Chicago, IL, ²Medical Social Sciences, Northwestern University, Chicago, IL, ³Medicine, Northwestern University, Chicago, IL, ⁴Surgery, Northwestern University, Chicago, IL
*Purpose: Cognitive impairment (CI) is highly prevalent in liver cirrhosis. Improvement after liver transplant (LT) varies among patients, diminishing the benefits of LT for some.…
2019 American Transplant Congress
Bile Duct Anastomosis over Intraluminal Plastic Biliary Stent in Liver Transplant: Clinical Outcome
H. Samant¹, K. Patel¹, W. Manatsathit², N. Singh¹, H. S. Amiri³, G. Zibari³
¹Louisiana State University and Health Science Center, Shreveport, LA, ²University of Nebraska Meical Center, Omaha, NE, ³John C McDonald Transplant Center, Shreveport, LA
*Purpose: Biliary complications have been known as “Achilles Heel” of orthotropic liver transplantation (OLT) with high morbidity and mortality. Intra-luminal plastic biliary stents replacing T-tubes…
2019 American Transplant Congress
Ikaros/IRF4 Signaling Regulates SIRT1-Mediated Macrophage M2 Shift in Liver Ischemia-Reperfusion Injury: From Mouse-to-Human
K. Kadono¹, K. Nakamura¹, H. Hirao¹, S. Kageyama¹, K. J. Dery¹, T. Ito¹, J. Aziz¹, X. Li², B. Ke¹, R. W. Busuttil¹, J. W. Kupiec‐Weglinski¹
¹Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA, ²NIEHS, Durham, NC
*Purpose: Hepatic ischemia-reperfusion injury (IRI) represents a risk factor for early graft dysfunction and rejection in liver transplantation (LT). Despite the efficacy of Sirtuin 1…
2019 American Transplant Congress
The Feasibility Of Donation After Cardiac Death In Liver Transplantation: A Registry Analysis
A. C. Gruessner, R. Misawa, A. Masi, Z. Moghadamyeghaneh, J. F. Renz, R. W. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Utilization of liver allografts from donation after cardiac death (DCD) has gradually increased in the United States. We aimed to analyze overall utilization of…