Articles tagged "Liver transplantation"

2020 American Transplant Congress
The Liver Outcome Monitoring Registry Consortium: Data and Preliminary Outcome Results
J. Case¹, S. Kurian¹, B. Barrick¹, A. Robinson², M. Prentice², C. Marsh¹
¹Scripps Center for Organ and Cell Transplantation, La Jolla, CA, ²United Network for Organ Sharing Research Department, Richmond, VA
*Purpose: The Liver Outcome Monitoring Registry (LOMR) is an online platform for collecting and monitoring liver outcome data of marginal and DCD organs to be…
2020 American Transplant Congress
Management of Pancreatic Cancer after Liver Transplantation: A 27-Year Single-Center Experience
I. A. Ziogas, M. A. Rauf, L. K. Matsuoka, M. I. Montenovo, M. Izzy, S. P. Alexopoulos
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The occurrence of de novo cancer after liver transplant (LT) is a leading cause of post-LT mortality and can be partially attributed to the…
2020 American Transplant Congress
Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates
A. Kardashian¹, J. Ge¹, C. McCulloch¹, M. R. Kappus², M. A. Dunn³, A. Duarte-Rojo³, M. L. Volk⁴, R. S. Rahimi⁵, E. C. Verna⁶, D. R. Ganger⁷, D. Ladner⁷, J. L. Dodge¹, B. Boyarsky⁸, M. McAdams-DeMarco⁸, D. L. Segev⁸, J. C. Lai¹
¹UCSF, SF, CA, ²Duke, Durham, NC, ³UPMC, Pittsburgh, PA, ⁴LLU, Loma Linda, CA, ⁵BSWH, Dallas, TX, ⁶Columbia, NY, NY, ⁷Northwestern, Chicago, IL, ⁸JHMI, Baltimore, MD
*Purpose: Frailty is associated with mortality in liver transplant (LT) waitlist candidates. We developed the Liver Frailty Index (LFI) to assess frailty in patients with…
2019 American Transplant Congress
Mortality around the One-Year Survival Metric after Liver Transplantation in the United States
C. Blebea¹, P. Chatterjee², A. Nathan¹, J. Diamond¹, H. J. Goldberg², A. Courtwright¹
¹Hospital of the University of Pennsylvania, Philadelphia, PA, ²Brigham and Women’s Hospital, Boston, MA
*Purpose: Liver transplant programs in the United States are evaluated on one-year survival, among other factors. This may create an unintended incentive to continue life-sustaining…
2019 American Transplant Congress
Karnofsky Performance Score as a Predictor of Acute Cellular Rejection Post Liver Transplantation
N. Kapila¹, K. Al Khalloufi², F. Salomon³, K. Kapila⁴, A. Gupta³, X. B. Zervos²
¹Gastroenterology and Hepatology, Cleveland Clinic Florida, Weston, FL, ²Transplant, Cleveland Clinic Florida, Weston, FL, ³Internal Medicine, Cleveland Clinic Florida, Weston, FL, ⁴Internal Medicine, University of Miami/JFK Medical Center, Atlantis, FL
*Purpose: The incidence of acute cellular rejection (ACR) following liver transplantation (LT) ranges from 20-40%. Development of ACR is associated with increased risk of graft…
2019 American Transplant Congress
Comprehensive and Combined Transcriptomic and Proteomic Analysis Reveals Key Factors Underlying Ischemia-Reperfusion Injury in Human Liver Transplantation
S. Huang, X. He, C. Sun, Z. Guo, W. Ju, Z. Zhu, Q. Zhao, G. Chen
Organ Transplant Center, the First Affiliated Hospital of SYSU, Guangzhou, China
*Purpose: Ischemia-reperfusion injury (IRI) is a major challenge in liver resection and liver transplantation surgery. Hepatic IRI can seriously impair liver function and even cause…
2019 American Transplant Congress
Clinical Features and Prognosis of Diffuse Intrahepatic Biliary Stricture in Adult ABO-Incompatible Living Donor Liver Transplantation
J. Kwon, G. Song, S. Hwang, K. Kim, C. Ahn, D. Moon, T. Ha, D. Jung, G. Park, Y. Yoon, H. Cho, I. Jeong, J. Choi, S. Yoo, S. Lee
Division of Liver Transplantation and Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of
*Purpose: Despite the advancement in desensitization protocol, diffuse intrahepatic biliary stricture (DIHBS), an attenuated form of antibody mediated rejection (AMR), remains an unresolved problem. As…
2019 American Transplant Congress
Results of Litmus (nct 02541916): The Liver Immune Tolerance Bio Marker Utilization Study
A. Chruscinski¹, V. Rojas-Luengas¹, S. Moshkelgosha¹, J. Luo², H. Yowanto², Z. Galvin¹, L. Lilly¹, R. Smith¹, E. Renner¹, J. Zhang¹, D. Grant¹, O. Adeyi¹, H. Atkins³, P. Juni⁴, N. Selzner¹, S. Juvet¹, G. Levy¹
¹Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada, ²Sciex, Brea, CA, ³Ottawa Hospital Research Institute, Ottawa, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada
*Purpose: Previously we reported a novel biomarker gene set for the identification of tolerance in murine models of rapamycin-induced cardiac tolerance and spontaneous hepatic tolerance.…
2019 American Transplant Congress
Alcohol Recidivism In Liver Transplant Recipients With Alcoholic Liver Disease: Does Six-months Abstinence Rule Still Holds True?
S. K. Satapathy¹, C. Thornburgh¹, J. Yu², J. Eason¹, S. Kedia², D. Maluf¹
¹UTHSC, Memphis, TN, ²University of Memphis, Memphis, TN
*Purpose: Liver transplant for alcoholic liver disease (ALD) continues to be a challenge for transplant centers, particularly related to the ethical dilemma of transplanting or…
2019 American Transplant Congress
Global and Domain Specific Cognition in Liver Transplant Recipients
D. Ko¹, L. Bratzke²
¹School of Nursing, Vanderbilt University, Nashville, TN, ²School of Nursing, University of Wisconsin-Madison, Madison, WI
*Purpose: Liver transplant (LT) recipients may experience global or domain-specific cognitive impairment (CI) (e.g., attention and memory) post-transplant due to multiple potential factors such as…