Articles tagged "Liver transplantation"

2020 American Transplant Congress
Perioperative Predictors of Acute Kidney Injury among Liver Transplant Recipients
R. Berkowitz¹, N. Douville², G. Mentz², P. Sharma³, C. Sonnenday¹
¹Surgery, Michigan Medicine, Ann Arbor, MI, ²Anesthesiology, Michigan Medicine, Ann Arbor, MI, ³Gastroenterology, Michigan Medicine, Ann Arbor, MI
*Purpose: We examined the perioperative and intraoperative risk factors associated with post-operative acute kidney injury (AKI) at post-op 7 days and 30-day estimated glomerular filtration…
2020 American Transplant Congress
Initial Experience of the First 13 Cases of Purely Laparoscopic Living Donor Right Hepatectomy
H. Choi¹, C. Seo¹, J. Ahn¹, G. Na², Y. You¹
¹Department of Surgery, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Department of Surgery, Bucheon St. Mary’s Hospital, The Catholic University of Korea, Bucheon, Korea, Republic of
*Purpose: Laparoscopic major hepatectomy is gradually increasing with two consensus meetings. However, purely laparoscopic donor right hepatectomy (PLDRH) is still being performed carefully, because donor…
2020 American Transplant Congress
Perioperative Management and Post-Liver Transplantation Outcomes in Methylmalonic Acidemia, Propionic Acidemia and Urea Cycle Disorders: 20 Years’ Experience
P. Vuong¹, N. Ebel², A. Brubaker¹, P. Than¹, C. Baker², A. Pedroza¹, K. Taylor¹, S. Conlon¹, D. Romero¹, G. Enns², C. Esquivel¹
¹Surgery, Stanford University, Palo Alto, CA, ²Pediatrics, Stanford University, Palo Alto, CA
*Purpose: To examine long-term outcomes after liver transplantation for organic acidemias and urea cycle defects at our center which utilizes standardized pre-, peri- and post-operative…
2020 American Transplant Congress
Galectin-3 as a Biomarker of Disease Severity in Acute-on-Chronic Liver Failure
E. Cervantes-Alvarez¹, F. Tejeda-Dominguez², M. Lizardo-Thiebaud², E. Alatorre-Arenas³, O. Méndez-Guerrero¹, S. Yarza-Regalado¹, D. Kershenobich¹, A. Torre¹, M. Vilatobá⁴, C. A. Huang⁵, N. Navarro-Alvarez¹
¹Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Molecular Biology, Panamerican University, School of Medicine, Mexico City, Mexico, ³University of the Americas Puebla, School of Medicine, Puebla, Mexico, ⁴Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Surgery, University of Colorado Anschutz Medical Campus, Denver, CO
*Purpose: A matter of great importance is the discovery of alternative diagnostic measures that can detect liver disease at an early stage, especially when at…
2020 American Transplant Congress
Living versus Deceased Donor Liver Transplantation in Cholestatic Liver Disease: An Analysis of the OPTN Database
I. A. Ziogas¹, S. P. Alexopoulos¹, L. K. Matsuoka¹, S. K. Geevarghese¹, L. D. Gorden¹, S. J. Karp¹, J. D. Perkins², M. I. Montenovo¹
¹Vanderbilt University Medical Center, Nashville, TN, ²University of Washington, Seattle, WA
*Purpose: The current MELD allocation system does not accurately reflect the urgency of liver transplantation (LT) in cholestatic liver disease (CLD) patients. Therefore, more CLD…
2020 American Transplant Congress
Hypernatremia Predicts Waitlist Death and Deterioration, but Not Post-Transplant Outcomes in Pediatric Liver Transplant Candidates
L. Thalji¹, N. Thalji², S. Ibrahim³, J. Heimbach², P. Kamath⁴, D. Haile¹, D. Kor¹
¹Anesthesiology, Mayo Clinic, Rochester, MN, ²Surgery, Mayo Clinic, Rochester, MN, ³Pediatric Gastroenterology, Mayo Clinic, Rochester, MN, ⁴Gastroenterology, Mayo Clinic, Rochester, MN
*Purpose: Pre-transplant hypernatremia has been shown to predict post-transplant mortality in adult liver transplant (LT) recipients. The effects of hypernatremia in children, however, remain unexplored.…
2020 American Transplant Congress
Characterization of a Clinically Scaled Bioengineered Liver Seeded with Primary Hepatocytes and Endothelial Cells
D. S. Davidow¹, J. J. Ross¹, B. D. Anderson¹, A. Stumbras¹, A. A. Katane¹, R. Lindeman¹, B. G. Steiner¹, A. Mendenhall¹, K. Gahlbeck¹, S. Armstrong¹, B. P. Amiot², E. D. Nelson², T. Gilbert¹, S. L. Nyberg²
¹Miromatrix, Eden Prairie, MN, ²Mayo Clinic, Rochester, MN
*Purpose: Advancements in whole organ bioengineering have the potential to offer solutions to a chronically insufficient donor organ supply. We recently demonstrated an ability to…
2020 American Transplant Congress
Increasing Prevalence and Diversity: Alcoholic Liver Disease in Liver Transplant Candidates
M. Joshi, E. L. Godfrey, J. A. Goss, A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: Increasing global alcohol use translates to a marked growth in alcoholic liver disease (ALD). ALD patients comprise a larger proportion of listings for liver…
2020 American Transplant Congress
Cirrhosis-Driven Immune Dysfunction is Associated with Poor Response to DEB-TACE and Waitlist Dropout in Hepatocellular Carcinoma Patients While Awaiting Liver Transplantation
K. Nunez, T. Sandow, M. Hibino, A. Cohen, P. Thevenot
Ochsner Health System, New Orleans, LA
*Purpose: Hepatocellular carcinoma (HCC) recurrence after transplantation is associated with higher tumor grade on explant, failure to respond to DEB-TACE, and pretreatment lymphopenia. We prospectively…
2020 American Transplant Congress
TIM-4+ Kupffer Cells Play Homeostatic Roles in Liver Ischemia Reperfusion Injury
M. Ni¹, J. Zhang¹, R. Sosa², S. Kageyama¹, R. Busuttil¹, R. Elaine², J. Kupiec-Weglinski¹, X. Wang³, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²Pathology, David Geffen School of Medicine-UCLA, Los Angeles, CA, ³Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Liver ischemia reperfusion injury (IRI) remains a significant clinical problem. Although the molecular mechanism of liver inflammatory response against IR has been studied extensively,…