Articles tagged "Liver transplantation"

2020 American Transplant Congress
Incidence of Chronic Kidney Disease after Liver Transplantation Using Measured GFR
N. R. Mazumder¹, J. Levitsky¹, G. Saracino², G. Klintmalm³, J. Trotter², S. Asrani²
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Transplant Hepatology, Baylor University Medical Center Dallas, Dallas, TX, ³Transplant Surgery, Baylor University Medical Center Dallas, Dallas, TX
*Purpose: Historical rates of ESRD after LT are 8% (1 year) and 18% (5 years) (Ojo NEJM 2003). However, these rates were based older estimates…
2020 American Transplant Congress
A Proof-of-Principle Study to Evaluate Autologous Hematopoietic Stem Cell Transplantation for Allogeneic Organ Transplant Tolerance (ASCOTT)
A. Chruscinski¹, S. Juvet¹, S. Moshkelgosha¹, E. Renner¹, L. Lilly¹, N. Selzner¹, C. Bredeson², O. Adeyi¹, S. Fischer¹, A. Demetris³, J. Zhang¹, M. Epstein¹, A. Clement², K. Khalili¹, Z. Galvin¹, A. Humar¹, T. Kim¹, K. Tinckham¹, T. Yi¹, G. Levy¹, H. Atkins²
¹Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada, ²The Ottawa Hospital, Ottawa, ON, Canada, ³University of Pittsburgh, Pittsburgh, PA
*Purpose: Long-term survival of recipients of solid organ transplants is limited by chronic rejection, disease recurrence and immunosuppression-induced toxicity. Self-tolerance is established after autologous hematopoietic…
2020 American Transplant Congress
Waitlist Mortality in Children with Biliary Atresia: A Competing Risks Analysis
I. A. Ziogas, F. Ye, Z. Zhao, L. K. Matsuoka, M. I. Montenovo, S. P. Alexopoulos
Vanderbilt University Medical Center, Nashville, TN
*Purpose: Biliary atresia (BA) is the most common indication for liver transplant (LT) in children. The current PELD allocation algorithm does not accurately reflect the…
2020 American Transplant Congress
Readmission Outcomes of Bariatric Surgery in Liver Transplant Recipients
R. A. Choudhury¹, D. Yoeli¹, H. Yaffe¹, H. B. Moore¹, G. Hoeltzel², A. Schulick¹, P. L. Abt³, K. Dumon⁴, K. D. Conzen¹, J. J. Pomposelli¹, E. A. Pomfret¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: Bariatric surgery has increasingly been offered for morbidly obese patients prior to liver transplantation with the hope of improving both waitlist candidacy and post-transplant…
2020 American Transplant Congress
Center Effects on Post-Transplant Outcomes in Liver Transplantation for Hilar Cholangiocarcinoma
S. Nagai¹, T. Kitajima¹, G. Sapisochin², D. Moonka¹, T. Hibi³
¹Henry Ford Hospital, Detroit, MI, ²University of Toronto, Toronto, ON, Canada, ³Kumamoto University, Kumamoto, Japan
*Purpose: Based on favorable outcomes reported by experienced centers, perihilar cholangiocarcinoma (Ph-CCA) has become an accepted indication for liver transplantation (LT). In the United States,…
2020 American Transplant Congress
Different Prognostic Impact of Liver Transplantation According to Liver Disease Etiologies
S. Nagai, T. Kitajima, S. Yeddula, D. Moonka, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud
Henry Ford Hospital, Detroit, MI
*Purpose: Disease specific background is not taken into consideration in the MELD-Na score based liver transplant (LT) allocation system. We hypothesized that optimal timing of…
2020 American Transplant Congress
Pig-To-Baboon Liver Xenotransplantation Utilizing Genetically Modified Swine
D. Detelich¹, C. G. Rickert¹, T. M. Coe¹, S. Kimura¹, I. Rosales¹, H. Deng¹, H. Yeh¹, W. Qin², Y. Kan², J. Layer², M. Youd², W. Westlin², L. Yang², J. F. Markmann¹
¹Massachusetts General Hospital, Boston, MA, ²eGenesis, Cambridge, MA
*Purpose: Pig-to-baboon liver xenotransplant (LXT) continues with significant hurdles, including thrombocytopenia, coagulation dysregulation and rejection with the longest reported survival of 29 days utilizing a…
2020 American Transplant Congress
Use of Cell Saver Leads to Lower Consumption of Blood Products During Liver Transplantation
R. Danc
Anesthesiology, Ikem, Prague, Czech Republic
*Purpose: Liver transplantation is often accompanied by significant blood loss and consequently a large consumption of blood products. In recent years, there has been a…
2020 American Transplant Congress
Predictors and Outcomes of Acute Graft versus Host Disease after Liver Transplant
A. Caines¹, D. Moonka², S. Nagai³, R. Salgia²
¹Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI, ²Hepatology, Henry Ford Health System, Detroit, MI, ³Transplant Surgery, Henry Ford Health System, Detroit, MI
*Purpose: Graft-versus-Host Disease (GVHD) is a rare complication of liver transplant (LT) with an estimated incidence of 0.1-2% per year and a high mortality. There…
2020 American Transplant Congress
The Relationship Between Frailty and Performance Status in Patients with Cirrhosis Awaiting Liver Transplantation
C. Q. Xu¹, F. Yao², Y. Mohamad², R. Wong², D. Kent², S. Seetharaman², Y. Srisengfa², J. C. Lai²
¹Department of Medicine, UCSF, San Francisco, CA, ²Division of Gastroenterology and Hepatology, Department of Medicine, UCSF, San Francisco, CA
*Purpose: Frailty—a multi-dimensional construct that encapsulates physical function, performance status, and nutritional status—has emerged as a critical determinant of mortality in patients with cirrhosis. Currently,…