Articles tagged "Liver transplantation"

2022 American Transplant Congress
Impact of Sarcopenia Using L3 and Thigh Skeletal Muscle Index on Clinical Outcomes in Liver Transplantation Recipient
M. Lim, J. Kim
Department of Surgery, Samsung Medical Cener, Seoul, Korea, Republic of
*Purpose: Sarcopenia is defined as loss of muscle mass and function. It has been reported as a significant risk factor for outcome after Liver transplantation…
2022 American Transplant Congress
Acute Cellular Rejection in Liver Transplant Recipients Following Vaccination Against Covid-19
R. Sarwar¹, O. Adeyi², N. Lim¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN
*Purpose: The coronavirus disease 2019 (COVID-19) global pandemic has seen the development of effective vaccines in record time. We report a series of five liver…
2022 American Transplant Congress
Evaluating the Performance and External Validity of Machine Learning-Based Prediction Models in Liver Transplantation: An International Study
T. Ivanics¹, D. So², M. P. Claasen³, D. Wallace⁴, M. Patel⁵, A. Gravely⁶, K. Walker⁷, T. Cowling⁷, L. Erdman⁸, G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²The Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada, ⁴Department of Health Services Research and policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁵Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX, ⁶Multi-organ transplant program, University of Toronto - University Health Network, Toronto, ON, Canada, ⁷Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁸The Centre of Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: National liver transplant (LT) registries are curated in many countries. We compared data from three national registries and developed machine learning algorithm (MLA)-based models…
2022 American Transplant Congress
Analytical Evaluation and Comparison to STR of an Accurate and Sensitive Microchimerism Monitoring Tool for Liver Transplant Recipients
A. S. Kothari¹, C. Egidio¹, J. Miles², N. Gulbahce¹, S. Dholakia³, M. Grskovic⁴
¹Clinical Development, CareDx, South San Francisco, CA, ²Medical Affairs, CareDx, Brooklyn, NY, ³Medical Affairs, CareDx, South San Francisco, CA, ⁴CareDx, Brisbane, CA
*Purpose: Peripheral blood chimerism is associated with clinically relevant events post liver transplantation (LT). Accurate quantification of donor chimerism in LT recipients with ultra-sensitive chimerism…
2022 American Transplant Congress
Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)
D. J. Reich¹, A. Schlegel², M. Rizzari³, D. Foley⁴, M. DeVera⁵, W. Chapman⁶, G. Roll⁷, A. Saharia⁸, C. Quintini⁹, S. Florman¹⁰, S. Merani¹¹, S. Mao¹², A. Pinna¹³, M. Akoad¹⁴, C. Kubal¹⁵, S. Alexopoulos¹⁶, H. Bohorquez¹⁷
¹Drexel University, Philadelphia, PA, ²Careggi U, Florence, Italy, ³Henry Ford, Detroit, MI, ⁴U Wisconsin, Madison, WI, ⁵Loma Linda, Loma Linda, CA, ⁶Washington U, Saint Louis, MO, ⁷UCSF, SF, CA, ⁸Methodist, Houston, TX, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Mount Sinai, NY, NY, ¹¹U Nebraska, Omaha, NE, ¹²Mayo, Jacksonville, FL, ¹³Cleveland Clinic, Weston, FL, ¹⁴Lahey, Burlington, MA, ¹⁵Indiana U, Indianapolis, IN, ¹⁶Vanderbilt, Nashville, TN, ¹⁷Ochsner, New Orleans, LA
*Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
2022 American Transplant Congress
Tele-Health Implementation During Covid19 Pandemic in Liver Transplant Population: A Focus on Medication Adherence, Patient Satisfaction, Clinical Outcomes and Possible Cost Impact
H. Joharji, S. Alghamdi, S. Alqahtani, M. F. Janju, J. Khader, D. Alissa, A. Aljedai, D. Alkortas, K. Bezaizi, D. Broering, A. Ajlan, W. K. Al-Hamoudi, E. Devol, A. Albinmosa, S. Alabbad, Z. Alabdulkarim, A. Zidan, R. Alamawi, E. Alshammari, E. Alharthi, D. Al-Anazi, A. Almalki, M. Alasmari
Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: The COVID-19 pandemic affected many aspects of health care, including the provision of care in ambulatory care clinics, necessitating the utilization of telehealth. For…
2022 American Transplant Congress
The Centennial Liver Allograft – Liver Function for Over 100 Years in 2 Different Individuals the Centennial Liver Allograft – Liver Function for Over 100 Years in 2 Different Individuals the Centennial Liver Allograft – Liver Function for Over 100 Years in 2 Different Individuals
R. Gruessner, J. Renz, A. C. Gruessner
Medicine, SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We investigated the occurrence of deceased-donor liver transplants (DDLT) that have achieved or came close to 100 years of function first in the donor…
2022 American Transplant Congress
A New Chapter In An Evolving Pandemic: Successful Pediatric Liver Transplantation With Covid+ Donors
M. B. Goss¹, F. Munoz², E. A. Moulton³, S. Pouch⁴, S. Koohmaraie⁵, N. Moreno¹, J. Goss³, N. Galvan³
¹McGovern Medical School, Houston, TX, ²Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ³Baylor College of Medicine, Houston, TX, ⁴Emory University School of Medicine, Decatur, GA, ⁵Texas Children's Hospital, Houston, TX
*Purpose: We report the first two pediatric liver transplants utilizing allografts from COVID+ donors, infected at time of organ procurement, demonstrating a pivotal step toward…
2022 American Transplant Congress
Variation in Adult Living Donor Liver Transplantation in the United States: Identifying Opportunities for Increased Utilization
K. Lentine¹, D. Axelrod², M. Schnitzler¹, R. Li¹, M. Dew³, T. Bitterman⁴, K. Olthoff⁴, J. Locke⁵, S. Emre⁶, H. Hunt⁷, T. Tanaka², A. Liapakis⁶
¹Saint Louis University, St. Louis, MO, ²U Iowa, Iowa City, IA, ³U Pittsburgh, Pittsburgh, PA, ⁴U Penn, Philadelphia, PA, ⁵UAB, Birmingham, AL, ⁶Yale, New Haven, CT, ⁷UNOS, Richmond, VA
*Purpose: To assess barriers to living donor liver transplant (LDLT) access in light of convincing evidence of survival benefits for patients with end-stage liver disease.*Methods:…
2022 American Transplant Congress
Center-Level Variability in DDLT Rate Before and After the Implementation of MMaT/250 Score
T. Ishaque, J. Beckett, B. King, J. G. Wang, D. Segev, A. Massie
Johns Hopkins Medical Institutions, Baltimore, MD
*Purpose: In 02/2020, OPTN replaced DSA/regional boundaries with acuity circles and substituted exception scores for individual patients to median-MELD-at-transplant within 250 nautical miles of a…