Articles tagged "Liver transplantation"

2022 American Transplant Congress
Utility of Donor Derived Cell-Free DNA in Liver Transplantation
A. Zarrinpar, D. Lewis, C. Warren, S. Duarte
Surgery, University of Florida, Gainesville, FL
*Purpose: As a non-invasive measure of allograft injury, quantifying the fraction of donor-derived cell-free DNA (dd-cfDNA) has proven to be useful technique in kidney transplantation.…
2022 American Transplant Congress
National Landscape of the Utilization of Living Donor Liver Allografts in Redo Liver Transplantation
J. I. López, K. Nijhar, J. Mitchell, L. Bowles Zeiser, K. Key, A. Asamoah-Mensah, A. Thomas, R. Haneda, S. K. Romano, J. Huang, A. Massie, A. M. Cameron, D. L. Segev, E. A. King
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: To examine the use of living donor liver allografts in patient’s requiring redo liver transplantation.*Methods: Using data from SRTR 2009-2020, we evaluated the number…
2022 American Transplant Congress
Practices and Perceptions of Living Donor Liver Transplant, Non-Directed Donation, and Liver Paired Exchange: A National Survey
A. Kaplan¹, R. Rosenblatt¹, W. Jackson², R. Brown¹, B. Samstein¹
¹New York Presbyterian Weill Cornell, New York, NY, ²University of Colorado Denver, Denver, CO
*Purpose: Living donor liver transplant (LDLT) remains under-utilized in the United States. The aim of this study, therefore, was to assess the perceptions and practices…
2022 American Transplant Congress
Investigating RNA Interference-Mediated Inhibition of Liver Ischemia Reperfusion Injury During Liver Preservation
J. E. Buchwald¹, D. Echeverria², J. Sousa², N. McHugh², A. Khvorova², P. N. Martins³
¹RNA Therapeutics Institute, Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA, ²RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, ³Department of Surgery, University of Massachusetts Chan Medical School, Worcester, MA
*Purpose: Liver transplantation cures acute end-stage and chronic liver diseases, yet current strategies of organ preservation including static cold storage (SCS) and machine perfusion (MP)…
2022 American Transplant Congress
Renal Failure is Reversible in the Majority of Patients Transplanted for Alcohol-Associated Hepatitis: A Review of the UNOS Database
Y. Bekki, G. Im, T. Schiano, S. Florman
Icahn School of Medicine at Mount Sinai, RMTI, New York, NY
*Purpose: The simultaneous liver-kidney (SLK) allocation policy in 2017 created Safety Net kidney allocation priority for liver transplant (LT) recipients with renal failure. Renal failure…
2022 American Transplant Congress
Locoregional Therapy for Hepatocellular Carcinoma Decreases Liver Transplant Waitlist Dropout and Mortality
S. Weeks, T. Ishaque, A. Massie, D. Segev, E. King
Johns Hopkins, Baltimore, MD
*Purpose: Liver transplant candidates with hepatocellular carcinoma (HCC) risk tumor progression that may disqualify them from transplant eligibility while awaiting HCC exception points on the…
2022 American Transplant Congress
Immune Checkpoints, Immune Cells, and MHC Expression in the Tumor Microenvironment of Resected Hepatocellular Carcinomas
A. Baquerizo¹, V. Vavinskaya², S. Bagsic¹, A. Rojas³, A. Mhoyan⁴, C. Frenette¹, L. Sher⁵, M. Romero³, J. Fisher¹, C. Marsch¹, R. Schaffer¹
¹Scripps, La Jolla, CA, ²UCSD, San Diego, CA, ³University, Seville, Spain, ⁴Kaiser, San Diego, CA, ⁵USC, Los Angeles, CA
*Purpose: Advances in tumor biology has shown the important role of the tumor microenvironment (TME) in tumor growth and metastasis. A better understanding of the…
2022 American Transplant Congress
Sars-cov2 Antibody Kinetics and Durability Three and Six Months After Two-Doses of MRNA Vaccination in Liver Transplant Recipients
A. Chang¹, A. T. Strauss¹, T. P. Chiang¹, A. Jennifer¹, H. Nicole¹, L. Zeiser¹, B. Boyarsky¹, R. Avery¹, A. Tobian¹, M. Levan¹, D. Warren¹, A. Massie¹, J. Garonzik-Wang², D. Segev¹, W. Werbel¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Wisconsin School of Medicine, Madison, WI
*Purpose: nti-spike antibody response to SARS-CoV-2 vaccination is diminished in LT recipients compared to the general population so understanding durability for those that do respond…
2022 American Transplant Congress
Development of a Portable Device to Quantify Hepatic Steatosis in Donated Livers Using an AI Algorithm
S. Klinkachorn¹, C. J. Tsoi-A-Sue², R. R. Narayan², M. L. Melcher²
¹Computer Science, Stanford, Stanford, CA, ²Surgery, Stanford, Stanford, CA
*Purpose: An accurate estimation of liver fat content is necessary to predict how a donor liver will function after transplantation. This can be challenging at…
2022 American Transplant Congress
Development Process of Minimally Invasive Living Donor Liver Transplantation (from Pure Laparoscopic Explant Hepatectomy to Robotic Graft Implantation)
K. Suh, S. Hong, S. Lee, S. Suh, S. Hong, E. Han, Y. Choi, N. Yi, K. Lee
Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: With the accumulation of experience in pure laparoscopic hepatectomy, including donor hepatectomy, our center initiated a minimally invasive living donor liver transplantation (LDLT) program…