Articles tagged "Liver transplantation"

2021 American Transplant Congress
Are All DSA’s the Same? Are We Ready for Precision Medicine in Pediatric LT?
S. E. Shin¹, M. Lee¹, N. Yazigi², K. Khan², S. Kaufman², J. Ahn³, O. Timofeeva⁴, U. Ekong²
¹Georgetown University School of Medicine, Washington, DC, ²Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC, ³Biostatistics, Bioinformatics, & Biomathematics, Georgetown University, Washington, DC, ⁴Histocompatibility Laboratory, Dept. of Pathology & Laboratory Medicine, Georgetown University, Washington, DC
*Purpose: Donor-specific antibodies (DSA) play an uncertain role in rejection after liver transplantation (LT). We hypothesized that evaluation of epitope differences in HLA-DR/DQ mismatching can…
2021 American Transplant Congress
Liver Transplantation for COVID-19-associated Cholangiopathy
J. Blondeel¹, P. Meersseman², N. Gilbo¹, I. Jochmans¹, M. Sainz-Barriga¹, J. Pirenne¹, D. Monbaliu¹
¹Abdominal Transplantation Surgery, University Hospitals Leuven, Leuven, Belgium, ²Medical Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium
*Purpose: The hallmark viral pneumonia of coronavirus-19-disease (COVID-19) is often accompanied by important extra-pulmonary manifestations. Liver dysfunction occurs in up to 45% of COVID-19 patients,…
2021 American Transplant Congress
Nrf2 Assessment in Discarded Liver Allografts: A Role in Allograft Function and Salvage
O. Ahmed, M. Xu, F. Zhou, A. N. Wein, G. Upadhya, Y. Lin, W. Chapman
Surgery, Washington University School of Medicine, Saint Louis, MO
*Purpose: With mounting pressures to optimize organ availability for transplantation, there is a focus on reducing organ discard and attempting to resuscitate declined grafts for…
2021 American Transplant Congress
Quantiferon-tb Gold Plus in Liver Transplant Candidates: Single-center Experience
J. Simkins¹, M. A. Mendoza¹, A. Chandorkar¹, Y. Natori¹, S. Anjan¹, L. R. Arosemena¹, R. Vianna²
¹Medicine, University of Miami, Miami, FL, ²Surgery, University of Miami, Miami, FL
*Purpose: QuantiFERON-TB (QFT) is the preferred diagnostic test for latent tuberculosis infection (LTBI). The QFT-Gold Plus (QFT-Plus) data in OLT candidates is limited.*Methods: Our hospital…
2021 American Transplant Congress
Evaluation of the Conversion from Tacrolimus to Sirolimus in Liver Transplant Recipients
H. Bakhtiari¹, S. Todd², H. Snyder², D. Lo², M. Flynn²
¹Mercer University College of Pharmacy, Atlanta, GA, ²Emory University Hospital, Atlanta, GA
*Purpose: The purpose of this study was to compare outcomes in liver transplant patients maintained on standard calcineurin inhibitor (CNI) therapy with tacrolimus versus those…
2021 American Transplant Congress
Review of 10-Year Liver Explant Pathology Impact on Outcomes in a Single Center
Y. K. Kwon¹, L. Sher¹, S. Khemichian², J. Kahn², Y. Genyk¹
¹Hepatobiliary and Abdominal Transplant Surgery, University of Southern California, Los Angeles, CA, ²Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, CA
*Purpose: Explant pathology (EP) is an important prognostic factor after liver transplantation (LT) for hepatocellular carcinoma (HCC). The purpose of this study was to correlate…
2021 American Transplant Congress
Extreme Hyponatremia as a Risk Factor for Early Mortality After Liver Transplantation in the MELD-Sodium Era
T. Ivanics¹, S. Leonard-Murali¹, H. Mouzaihem¹, D. Moonka², T. Kitajima¹, S. Yeddula¹, T. Shamaa¹, M. Rizzari¹, K. Collins¹, A. Yoshida¹, M. Abouljoud¹, S. Nagai¹
¹Division of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, ²Division of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI
*Purpose: The impact of hyponatremia on waitlist and post-transplant outcomes following the implementation of MELD-Na based liver allocation remains unclear. We sought to evaluate waitlist…
2021 American Transplant Congress
Outcomes After Abo Incompatible Pediatric Liver Transplantation are Comparable to Abo Identical/compatible Transplant
C. Lemoine, K. Brandt, R. Superina
Division of Transplant and Advanced Hepatobiliary Surgery, Ann & Robert H. Lurie Children's Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: In order to evaluate if the incidence of vascular and biliary complications as well as patient and graft survival in ABO incompatible (ABOi) liver…
2021 American Transplant Congress
Impact of COVID-19 on Solid Organ Transplantation
E. Sampson¹, S. Hall², K. Robichaux³, A. Kumar², N. Kemmer⁴, J. Buggs⁵
¹Lake Erie College of Osteopathic Medicine, Tampa, FL, ²Morsani College of Medicine, University of South Florida, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Hepatology, Tampa General Hospital, Tampa, FL, ⁵Transplant Surgery, Tampa General Hospital, Tampa, FL
*Purpose: Patterns of racial disparities have been identified throughout the history of American medicine. In December 2019, COVID-19 was first detected and has had a…
2021 American Transplant Congress
Impact of Extended Living Donor Criteria on Donor Safety in Living Donor Liver Transplantation
J. KIM
Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of
*Purpose: Donor safety is major concern during living donor liver transplantation (LDLT) and most transplant centers accept strict selection criteria although some centers have been…